Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment.
对小梁网进行单细胞分析,发现青光眼模型中存在线粒体功能障碍,而维生素 B3 治疗可以保护这种功能障碍。
期刊:Elife
影响因子:6.4
doi:10.7554/eLife.107161
Tolman Nicholas, Li Taibo, Balasubramanian Revathi, Li Guorong, Pfeiffer Rebecca, Bupp-Chickering Violet, Kelly Ruth A, Simón Marina, Peregrin John, Montgomery Christa, Jones Bryan, Stamer W Daniel, Qian Jiang, John Simon W M