文献库，生知库 | 链接生命科学的每一步

Liu Xiao, Wang Jinbiao, Li Jipeng, Kang Lu, Wang Mengyan, Huang Zhaoyu, Man Jarrett, Huang Xuxu, Zhang Zhiming, Yang Fang, Bartlett Madelaine, Wu Liuji, Dong Zhaobin, Jackson David, Xu Fang

ERECT

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发表日期：2026

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Self-amplifying RNA therapy encoding CNTF with disulfiram co-delivery promotes optic nerve repair through microglial pyroptosis inhibition and RGC axonal regeneration

编码 CNTF 的自扩增 RNA 疗法与双硫仑共递送，可通过抑制小胶质细胞焦亡和促进 RGC 轴突再生来促进视神经修复。

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-026-04272-x

Zhang, Qianyue; Liu, Yusha; Wei, Qin; Song, Mingyang; Liu, Siwei; Zhang, Haiyang; Deng, Tingyu; Zhang, Chutong; Tan, Kexin; Huang, Rui; Ni, Ni; Zhang, Jun; Gu, Ping; Du, Gang; Li, Jipeng; Chen, Yingzhi; Zhou, Huifang; Fan, Xianqun

Exploring the optimal follow-up time for resectable colorectal cancer patients: a multicenter, five-year longitudinal cohort study

探讨可切除结直肠癌患者的最佳随访时间：一项多中心、为期五年的纵向队列研究

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-026-41611-2

Kang, Boyu; Qiao, Yihuan; Wang, Yiqian; Li, Yunlong; Hu, Baoliang; Zhang, Zecheng; Wang, Qi; Zhu, Jun; Li, Jipeng

Individualized intraoperative blood pressure control with norepinephrine reduces kidney injury biomarkers but not creatinine-defined acute kidney injury in older patients with hypertension undergoing major abdominal surgery: a single-center randomized controlled trial

在接受大型腹部手术的老年高血压患者中，采用去甲肾上腺素进行个体化术中血压控制可降低肾损伤生物标志物，但不能降低肌酐定义的急性肾损伤：一项单中心随机对照试验

期刊:BMC Anesthesiology

影响因子:2.6

doi:10.1186/s12871-025-03588-9

Li, Jipeng; Jiang, Huayong; Song, Qi-Liang; Jiang, Zong-Ming; Liu, Shuyun

Posterior Vitreous Detachment Determines the Clinical Impact of Fibrovascular Membrane Fibrosis After Anti-VEGF Treatment in Proliferative Diabetic Retinopathy: A Real-World Study

后玻璃体脱离决定增殖性糖尿病视网膜病变抗VEGF治疗后纤维血管膜纤维化的临床影响：一项真实世界研究

期刊:

影响因子:

doi:10.2147/OPTH.S554446

Zhao, Meng; Wang, Zhaoyang; Liu, Lin; O'Toole, Louise; Li, Jipeng

Organelle-oriented nanomedicines in tumor therapy: Targeting, escaping, or collaborating?

肿瘤治疗中以细胞器为靶点的纳米药物：靶向、逃逸还是协同作用？

期刊:Bioactive Materials

影响因子:20.3

doi:10.1016/j.bioactmat.2025.02.040

Tan, Kexin; Zhang, Haiyang; Yang, Jianyuan; Wang, Hang; Li, Yongqiang; Ding, Guqiao; Gu, Ping; Yang, Siwei; Li, Jipeng; Fan, Xianqun

ASPM mediates nuclear entrapment of FOXM1 via liquid-liquid phase separation to promote progression of hepatocarcinoma.

ASPM通过液-液相分离介导FOXM1的核内滞留，从而促进肝癌的进展

期刊:Genome Biology

影响因子:9.4

doi:10.1186/s13059-025-03526-5

Jiang Xunliang, Liu Jun, Wang Ke, Sun Jianyong, Yin Huilong, Jiang Yu, Liu Yongkang, Wang Ningbo, Ding Xiaochen, Gao Pu, Li Lin, Zhang Xiang, Li Jipeng, Zhang Rui

Cotrimoxazole for infection prevention in glomerulonephritis treated with rituximab: a randomized controlled trial

利妥昔单抗治疗肾小球肾炎患者使用复方新诺明预防感染：一项随机对照试验

期刊:BMC Medicine

影响因子:8.3

doi:10.1186/s12916-025-04491-3

Chen, Ye; Zha, Yang; Hu, Anlan; Yu, Xiaoyong; Ma, Baomei; Han, Jin; Xue, Xiaoxia; Lu, Rui; Li, Jipeng; Chen, Xiaolan; Jia, Qing; Shen, Xi; Zhao, Jing; Chang, Fengpei; He, Lijie

Development and validation of machine learning-based survival analysis to predict outcome in gastric cancer with adjuvant chemotherapy: A multicenter, longitudinal, cohort study

基于机器学习的生存分析方法在预测接受辅助化疗的胃癌患者预后中的应用：一项多中心、纵向队列研究

期刊:Chinese Journal of Cancer Research

影响因子:6.3

doi:10.21147/j.issn.1000-9604.2025.03.07

Pan, Yan; Lu, Linbin; Gao, Xianchun; Yu, Jun; Dai, Sitian; Yao, Ruirong; Han, Ning; Wang, Xinlin; Reyila, Abudurousuli; Wang, Shibo; Yan, Junya; Xu, Zhen; Lu, Yuanyuan; Li, Mengbin; Li, Jipeng; Liu, Jiayun; Zhao, Qingchuan; Wu, Kaichun; Nie, Yongzhan

Higher BMI reduces mortality in elderly and Stage III colorectal cancer patients: insights from a multicenter cohort study

较高的BMI可降低老年人和III期结直肠癌患者的死亡率：一项多中心队列研究的启示

期刊:Frontiers in Nutrition

影响因子:5.1

doi:10.3389/fnut.2025.1655707

Qiao, Yihuan; Kang, Boyu; Jiang, Yu; Zhang, Zecheng; Hu, Baoliang; Song, Jiawei; Ma, Hongjiang; Liu, Shuai; Du, Yongtao; Wang, Qi; Guo, Yajie; Qin, Shihao; Tan, Zhaobang; Zhu, Jun; Huang, Yi; Li, Jipeng

ERECTA genes and their ligands regulate shoot and inflorescence architecture in maize.

ERECTA 基因及其配体调控玉米的茎和花序结构。

Self-amplifying RNA therapy encoding CNTF with disulfiram co-delivery promotes optic nerve repair through microglial pyroptosis inhibition and RGC axonal regeneration

编码 CNTF 的自扩增 RNA 疗法与双硫仑共递送，可通过抑制小胶质细胞焦亡和促进 RGC 轴突再生来促进视神经修复。

Exploring the optimal follow-up time for resectable colorectal cancer patients: a multicenter, five-year longitudinal cohort study

探讨可切除结直肠癌患者的最佳随访时间：一项多中心、为期五年的纵向队列研究

Individualized intraoperative blood pressure control with norepinephrine reduces kidney injury biomarkers but not creatinine-defined acute kidney injury in older patients with hypertension undergoing major abdominal surgery: a single-center randomized controlled trial

在接受大型腹部手术的老年高血压患者中，采用去甲肾上腺素进行个体化术中血压控制可降低肾损伤生物标志物，但不能降低肌酐定义的急性肾损伤：一项单中心随机对照试验

Posterior Vitreous Detachment Determines the Clinical Impact of Fibrovascular Membrane Fibrosis After Anti-VEGF Treatment in Proliferative Diabetic Retinopathy: A Real-World Study

后玻璃体脱离决定增殖性糖尿病视网膜病变抗VEGF治疗后纤维血管膜纤维化的临床影响：一项真实世界研究

Organelle-oriented nanomedicines in tumor therapy: Targeting, escaping, or collaborating?

肿瘤治疗中以细胞器为靶点的纳米药物：靶向、逃逸还是协同作用？

ASPM mediates nuclear entrapment of FOXM1 via liquid-liquid phase separation to promote progression of hepatocarcinoma.

ASPM通过液-液相分离介导FOXM1的核内滞留，从而促进肝癌的进展

Cotrimoxazole for infection prevention in glomerulonephritis treated with rituximab: a randomized controlled trial

利妥昔单抗治疗肾小球肾炎患者使用复方新诺明预防感染：一项随机对照试验

Development and validation of machine learning-based survival analysis to predict outcome in gastric cancer with adjuvant chemotherapy: A multicenter, longitudinal, cohort study

基于机器学习的生存分析方法在预测接受辅助化疗的胃癌患者预后中的应用：一项多中心、纵向队列研究

Higher BMI reduces mortality in elderly and Stage III colorectal cancer patients: insights from a multicenter cohort study

较高的BMI可降低老年人和III期结直肠癌患者的死亡率：一项多中心队列研究的启示