日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Osimertinib with or without savolitinib as first-line treatment for MET-aberrant, EGFR-mutant NSCLC: randomized phase 2 trial (FLOWERS)

奥希替尼联合或不联合沙沃替尼作为MET异常、EGFR突变型非小细胞肺癌的一线治疗：随机2期试验（FLOWERS）

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67950-8
Li, Anna; Feng, Wei-Neng; Li, Juan; Xu, Bing-Fei; Zhao, Jun; Jia, Yun; Tang, Ke-Jing; Li, Yong-Sheng; Zhou, Cheng-Zhi; Fan, Yun; Xu, Chong-Rui; Sun, Yue-Li; Chen, Hua-Jun; Yan, Hong-Hong; Shi, Zong-Kun; Yang, Jin-Ji
肺癌
肿瘤
肿瘤免疫
EGF
EGFR
细胞生物学
MET
发表日期：2026
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Structure-Guided Engineering of a Promiscuous O-Methyltransferase for a SAM Regeneration Biocatalysis Platform of Methylated Pharmaceuticals

基于结构的工程改造，构建了一种具有广泛底物特异性的O-甲基转移酶，用于甲基化药物的SAM再生生物催化平台

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202517794
Xiong, Xiran; Song, Jun; Li, Shihan; Jin, Lu; He, Qi; Zhang, Baohui; Cao, Yan; Yi, Shanyong; Yang, Yanfang; Li, Xiang; Li, Juan; Huang, Wei
表观遗传
发表日期：2026
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(68)Ga/(177)Lu-labeled nectin4-targeted covalent bicyclic peptide: a novel nectin-4-targeted radioligands for theranostic of urothelial carcinoma

(68)Ga/(177)Lu标记的靶向nectin4的共价双环肽：一种用于尿路上皮癌诊疗的新型nectin-4靶向放射性配体

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-026-04253-0
Sun, Li; Zhu, Bin; Zuo, Ke; Bai, Liyan; Lei, Jialiang; Li, Ye; Liu, Xinyu; Pan, Xiaoyu; Li, Juan; Wu, Aiguo; Shen, Yijun; Xu, Xiaoping; Song, Shaoli
肿瘤
肿瘤免疫
发表日期：2026
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PHGDH-dependent serine metabolism in astrocytes: A key regulator of oxidative stress and pyroptosis in cerebral ischemia-reperfusion injury

星形胶质细胞中PHGDH依赖的丝氨酸代谢：脑缺血再灌注损伤中氧化应激和细胞焦亡的关键调节因子

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2025.103954
Zhang, Jimeng; Luo, Yaowen; Xie, Changcai; Zhang, Min; Qin, Heyao; Zhou, Yuefei; Wu, Xiuquan; Hu, Chenchen; Hu, Feiming; Fei, Xiaowei; Zhang, Hongchen; Li, Juan; Fu, Yihao; Yuan, Yunchao; Yang, Shuya; Gao, Dakuan
胶质细胞
表观遗传
PHGDH
氧化应激
神经科学
代谢
焦亡
细胞生物学
毒理研究
发表日期：2026
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Development of dual base editors based on ssDNA-targeting SCP1.201 deaminases for the artificial evolution of novel herbicide-tolerant OsEPSPS variants

基于靶向单链DNA的SCP1.201脱氨酶的双碱基编辑器的开发，用于人工进化新型耐除草剂OsEPSPS变体

期刊:Plant Communications
影响因子:11.6
doi:10.1016/j.xplc.2025.101632
Xu, Rongfang; Zhu, Jiahui; Wang, Hui; Wang, Huanhuan; Zhao, Liangxia; Liu, Xiaoshuang; Qin, Ruiying; Pan, Lang; Wei, Pengcheng; Li, Juan
碱基编辑
发表日期：2026
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Assessing the Accuracy of Global HFC-134a Satellite Observations from Atmospheric Chemistry Experiment Fourier Transform Spectrometer (ACE-FTS) via Aircraft, Balloon, and Model Comparisons

通过飞机、气球和模型对比评估大气化学实验傅里叶变换光谱仪（ACE-FTS）对全球HFC-134a卫星观测的准确性

期刊:Environmental Science & Technology
影响因子:11.3
doi:10.1021/acs.est.5c13191
Li, Yali; Li, Juan; Chen, Yuyang; Zhang, Longchang; Montzka, Stephen A; Vimont, Isaac; Crotwell, Molly; Liu, Song; Li, Xicheng; Fu, Weitao; Zhang, Peng; Zhang, Xue; Wu, Xingyi; Zhang, Jiaming; Huang, Yuchen; Luan, Xiangyu; Shen, Huizhong; Ye, Jianhuai; Wang, Chen; Yang, Xin; Fu, Tzung-May; Zhu, Lei
发表日期：2026
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NDUFS1-Mediated Mitochondrial Complex I Activity Maintains Pancreatic Cancer Stemness by Promoting PAX2 Hypomethylation

NDUFS1介导的线粒体复合物I活性通过促进PAX2低甲基化维持胰腺癌干性

期刊:MedComm
影响因子:10.7
doi:10.1002/mco2.70678
Fan, Xin-Yu; Li, Wen; Shi, Ying; Xu, Bao-Qing; Wang, Hao; Tian, Ruo-Fei; Duan, Zi-Chuan; Fan, Jing; Liu, Jia-Rong; Sun, Xiu-Xuan; Wang, Bin; Wang, Li-Juan; Wang, Ke; Wang, Shi-Jie; Yang, Xiang-Min; Cui, Hong-Yong; Chen, Zhi-Nan; Li, Ling
肿瘤
表观遗传
肿瘤免疫
线粒体
胰腺癌
发表日期：2026
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A natural remedy: Kidney-targeting nanoplatform for photoacoustic imaging-guided three-in-one theranostics of rhabdomyolysis-induced acute kidney injury

一种天然疗法：用于光声成像引导的横纹肌溶解症诱发急性肾损伤的肾脏靶向纳米平台三合一诊疗一体化治疗

期刊:Materials Today Bio
影响因子:10.2
doi:10.1016/j.mtbio.2026.103068
Zhao, Xuhui; Jin, Yarong; Han, Yahong; Zhang, Jin; Zhang, Qi; Ren, Shilei; Li, Juan; Liu, Shijie; Dong, Jie; Wu, Jingmiao; Fu, Xiaojing; Xu, Ting; Sun, Jinghua; Zhang, Ruiping
毒理研究
肾损伤
发表日期：2026
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Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.

双响应 PDA-HP 水凝胶可实现针对线粒体的温和光热疗法，用于脊髓修复。

期刊:Materials Today Bio
影响因子:10.2
doi:10.1016/j.mtbio.2026.102783
Li Yi, Hu Jiaxuan, Ran Bing, Zhong Huisheng, Zhong Nayin, Zhong Yi, Fu Xinyu, Liu Xinying, Wu Guanghua, Zhong Qinwen, Li Juan
线粒体
神经科学
发表日期：2026
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MPP7 inhibits tumor metastasis through promoting snail degradation in clear cell renal cell carcinoma.

MPP7 通过促进 snail 降解来抑制透明细胞肾细胞癌中的肿瘤转移。

期刊:Cellular & Molecular Biology Letters
影响因子:10.2
doi:10.1186/s11658-025-00825-4
Zhang Mi, Zhang Juan, Zhou Yan, Zhao Andi, Wang Hui, Wang Bo, Li Juan, Liu Peijun, Yang Jin
细胞生物学
发表日期：2026
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