Li Lequn相关文献与解析，生知库 | 链接生命科学的每一步

Targeting PD-1 and CD85j can restore intratumoral CD4(+) GzmB(+) T-cell functions to combat MHC-II-expressing tumors

靶向PD-1和CD85j可以恢复肿瘤内CD4(+)GzmB(+)T细胞的功能，从而对抗表达MHC-II的肿瘤。

doi:10.1136/jitc-2024-010890

Wang, Boyu; Wang, Xu; Wang, Tianlai; Meng, Kelin; Yu, Taiyan; Xi, Yu; Hu, Shaojie; Xiong, Hui; Qu, Rirong; Yuan, Zhiwei; Wang, Xue; Zeng, Chenxi; Zou, Wenbin; Tian, Yitao; Cai, Yixin; Fu, Shengling; Fu, Xiangning; Li, Lequn

IFN-γ-mediated suppression of ANGPT2-Tie2 in endothelial cells facilitates tumor vascular normalization during immunotherapy

IFN-γ介导的内皮细胞中ANGPT2-Tie2的抑制作用促进免疫治疗期间肿瘤血管的正常化。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1551322

Cai, Zihao; Meng, Kelin; Yu, Taiyan; Xi, Yu; Yuan, Zhiwei; Wang, Xue; Wang, Congjian; Li, Lequn; Fu, Xiangning

Analysis of tumor cell proliferation (Ki-67) and cell cycle regulator proteins in lung adenocarcinoma with different radiological subtypes.

对不同放射学亚型肺腺癌中肿瘤细胞增殖（Ki-67）和细胞周期调节蛋白进行分析

期刊:Respiratory Research

影响因子:5

doi:10.1186/s12931-025-03217-6

Qu Rirong, Zhang Yang, Qin Shenghui, Xiong Jing, Fu Xiangning, Li Lequn, Tu Dehao, Cai Yixin

Lnc-EST885 promotes hepatocellular carcinoma metastasis through PI3K / AKT pathway by interaction with TRAF4

Lnc-EST885通过与TRAF4相互作用，经由PI3K/AKT通路促进肝细胞癌转移。

期刊:Translational Oncology

影响因子:4.1

doi:10.1016/j.tranon.2024.102254

Zhu, Shaoliang; Wang, Gang; Zhang, Yuxuan; Zou, Mengjie; Li, Zhi; Qu, Shenhong; Zou, Xiaosu; Nong, Wenqian; Miao, Weiwei; Chen, Qicong; Mo, Juanmei; Chen, Huibing; Li, Lequn; Dong, Xiaofeng; Luo, Honglin

Transcatheter Arterial Chemoembolization May Be Selectively Indicated as Postoperative Adjuvant Therapy for Hepatocellular Carcinoma Patients with Microvascular Invasion

经导管动脉化疗栓塞术可选择性地作为肝细胞癌伴微血管侵犯患者的术后辅助治疗。

期刊:Journal of Hepatocellular Carcinoma

影响因子:3.4

doi:10.2147/JHC.S560567

Zeng, Jie; Huang, Hongyang; Tang, Minchao; Tao, Zheng; Mo, Kaixiang; Chen, Weijie; Su, Yuejiao; Su, Jinting; Liang, Rong; Lin, Yan; Li, Lequn; Wu, Guobin; Luo, Xiaoling; Ye, Jiazhou; Mai, Rongyun

The Role of Timing of Progression and Early Salvage Surgery in Unresectable Hepatocellular Carcinoma Treated with TACE Plus TKIs and PD‑1 Inhibitors

TACE联合TKI和PD-1抑制剂治疗不可切除肝细胞癌中疾病进展时机和早期挽救性手术的作用

期刊:Journal of Hepatocellular Carcinoma

影响因子:3.4

doi:10.2147/JHC.S481816

Li, Xingzhi; Tang, Zhihong; Pang, Qingqing; Wang, Xiaobo; Bai, Tao; Chen, Jie; Wei, Meng; Wei, Tao; Li, Lequn; Wu, Feixiang

TACE combined Lenvatinib plus Camrelizumab versus TACE alone in efficacy and safety for unresectable hepatocellular carcinoma: a propensity score-matching study

TACE联合乐伐替尼加卡瑞利珠单抗与单独TACE治疗不可切除肝细胞癌的疗效和安全性：一项倾向评分匹配研究

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/s12885-024-12484-3

Tang, Zhihong; Bai, Tao; Wei, Tao; Wang, Xiaobo; Chen, Jie; Ye, Jiazhou; Li, Shangqi; Wei, Meng; Li, Xingzhi; Lin, Youzhi; Tang, Juan; Li, Lequn; Wu, Feixiang

Bazedoxifene Inhibits Cell Viability, Colony-Forming Activity, and Cell Migration in Human Non-Small Cell Lung Cancer Cells and Improves the Treatment Efficacy of Paclitaxel and Gemcitabine

巴泽多昔芬抑制人非小细胞肺癌细胞的细胞活力、集落形成活性和细胞迁移，并提高紫杉醇和吉西他滨的治疗效果。

期刊:Clinical Respiratory Journal

影响因子:2.3

doi:10.1111/crj.13822

Huang, Yaochen; Lin, Jiayuh; Fu, Xiangning; Li, Lequn; Fu, Shenging

Outcomes and prognostic factors in initially unresectable hepatocellular carcinoma treated using conversion therapy with lenvatinib and TACE plus PD-1 inhibitors

采用乐伐替尼和TACE联合PD-1抑制剂进行转化治疗的初始不可切除肝细胞癌的疗效和预后因素

期刊:Frontiers in Oncology

影响因子:3.3

doi:10.3389/fonc.2023.1110689

Li, Xingzhi; Chen, Jie; Wang, Xiaobo; Bai, Tao; Lu, Shaolong; Wei, Tao; Tang, Zhihong; Huang, Chengwen; Zhang, Bin; Liu, Bowen; Li, Lequn; Wu, Feixiang

Intrinsic Properties of the Lymph Node Render It Immunologically Susceptible to Metastasis.

淋巴结的固有特性使其在免疫学上易受转移影响

Targeting PD-1 and CD85j can restore intratumoral CD4(+) GzmB(+) T-cell functions to combat MHC-II-expressing tumors

靶向PD-1和CD85j可以恢复肿瘤内CD4(+)GzmB(+)T细胞的功能，从而对抗表达MHC-II的肿瘤。

IFN-γ-mediated suppression of ANGPT2-Tie2 in endothelial cells facilitates tumor vascular normalization during immunotherapy

IFN-γ介导的内皮细胞中ANGPT2-Tie2的抑制作用促进免疫治疗期间肿瘤血管的正常化。

Analysis of tumor cell proliferation (Ki-67) and cell cycle regulator proteins in lung adenocarcinoma with different radiological subtypes.

对不同放射学亚型肺腺癌中肿瘤细胞增殖（Ki-67）和细胞周期调节蛋白进行分析

Lnc-EST885 promotes hepatocellular carcinoma metastasis through PI3K / AKT pathway by interaction with TRAF4

Lnc-EST885通过与TRAF4相互作用，经由PI3K/AKT通路促进肝细胞癌转移。

Transcatheter Arterial Chemoembolization May Be Selectively Indicated as Postoperative Adjuvant Therapy for Hepatocellular Carcinoma Patients with Microvascular Invasion

经导管动脉化疗栓塞术可选择性地作为肝细胞癌伴微血管侵犯患者的术后辅助治疗。

The Role of Timing of Progression and Early Salvage Surgery in Unresectable Hepatocellular Carcinoma Treated with TACE Plus TKIs and PD‑1 Inhibitors

TACE联合TKI和PD-1抑制剂治疗不可切除肝细胞癌中疾病进展时机和早期挽救性手术的作用

TACE combined Lenvatinib plus Camrelizumab versus TACE alone in efficacy and safety for unresectable hepatocellular carcinoma: a propensity score-matching study

TACE联合乐伐替尼加卡瑞利珠单抗与单独TACE治疗不可切除肝细胞癌的疗效和安全性：一项倾向评分匹配研究

Bazedoxifene Inhibits Cell Viability, Colony-Forming Activity, and Cell Migration in Human Non-Small Cell Lung Cancer Cells and Improves the Treatment Efficacy of Paclitaxel and Gemcitabine

巴泽多昔芬抑制人非小细胞肺癌细胞的细胞活力、集落形成活性和细胞迁移，并提高紫杉醇和吉西他滨的治疗效果。

Outcomes and prognostic factors in initially unresectable hepatocellular carcinoma treated using conversion therapy with lenvatinib and TACE plus PD-1 inhibitors

采用乐伐替尼和TACE联合PD-1抑制剂进行转化治疗的初始不可切除肝细胞癌的疗效和预后因素