Li Minjun相关文献与解析，生知库 | 链接生命科学的每一步

Su, Haixia; Nie, Tianqing; Chen, Guofeng; Xiong, Muya; Zhang, Yumin; Wu, Guoqing; You, Mengyuan; Xie, Hang; He, Jian; Xiong, Yanchao; Hu, Hangchen; Zhao, Wenfeng; Li, Minjun; Xiao, Gengfu; Zhang, Leike; Xu, Yechun

发表日期：2026

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Palmitic acid activates c-Myc via dual palmitoylation-dependent pathways to promote colon cancer

棕榈酸通过双重棕榈酰化依赖性途径激活c-Myc，从而促进结肠癌的发生。

期刊:Cell Discovery

影响因子:12.5

doi:10.1038/s41421-026-00869-6

Du, Wenxin; Zhang, Jianing; Wang, Yuexin; Li, Minjun; Cao, Ji; Yang, Bo; He, Qiaojun; Shao, Xuejing; Ying, Meidan

Efficacy and safety of tyrosine kinase inhibitors in advanced hepatocellular carcinoma patients with Child-Pugh A and B cirrhosis: a meta-analysis

酪氨酸激酶抑制剂治疗伴有Child-Pugh A级和B级肝硬化的晚期肝细胞癌患者的疗效和安全性：一项荟萃分析

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2026.1690890

Liu, Xionglin; Li, Jindu; Li, MinJun; Xiang, Bangde

De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS.

通过靶向 cGAS 的变构位点，从头设计蛋白质缩合抑制剂

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-60297-0

Zhao Wenfeng, Chen Guofeng, He Jian, Shen Xiaofang, Xiong Muya, Xiong Liwei, Qi Zhihao, Xie Hang, Li Wanchen, Li Jiameng, Dou Huixia, Hu Hangchen, Su Haixia, Shao Qiang, Li Minjun, Sun Hongbin, Xu Yechun

免疫/内分泌

发表日期：2025

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Structure-based design of potent and selective inhibitors targeting RIPK3 for eliminating on-target toxicity in vitro.

基于结构的高效选择性RIPK3抑制剂设计，可消除体外靶向毒性

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-59432-8

Su Haixia, Chen Guofeng, Xie Hang, Li Wanchen, Xiong Muya, He Jian, Hu Hangchen, Zhao Wenfeng, Shao Qiang, Li Minjun, Zhao Qiang, Xu Yechun

信号转导

发表日期：2025

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Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease

猴痘病毒I7L蛋白酶的动态帽介导底物进入和强效抑制剂设计

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202501625

Su, Haixia; Wu, Guoqing; Xiong, Muya; Wang, Yuhang; Cao, Junyuan; You, Mengyuan; Xiang, Yingchun; Nie, Tianqing; Li, Minjun; Xiao, Gengfu; Zhang, Leike; Shao, Qiang; Xu, Yechun

The crystal structure of GH57 family amylopullulanase reveals its dual binding pockets sharing the same catalytic dyad

GH57家族淀粉支链酶的晶体结构揭示了其两个结合口袋共享同一个催化二元体。

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-025-08192-8

Zhu, Zhimin; Wang, Weiwei; Li, Minjun; Xu, Qin; Zhou, Huan; Huang, Liqing; Wang, Qisheng; Yu, Feng

发表日期：2025

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Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening

利用晶体学片段筛选鉴定出针对人热休克蛋白90的基于片段的药物设计的新起始点

期刊:IUCrJ

影响因子:3.6

doi:10.1107/S2052252524012247

Huang, Liqing; Wang, Weiwei; Zhu, Zhimin; Li, Qianhui; Li, Minjun; Zhou, Huan; Xu, Qin; Wen, Wen; Wang, Qisheng; Yu, Feng

发表日期：2025

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ARID3A Promotes Tumor Progression by Activating TNF-α/NF-κB Signaling in Dual-Phenotype Hepatocellular Carcinoma

ARID3A通过激活TNF-α/NF-κB信号通路促进双表型肝细胞癌的肿瘤进展

期刊:Journal of Hepatocellular Carcinoma

影响因子:3.4

doi:10.2147/JHC.S549213

Li, Minjun; Yang, Taixin; Huang, Juntao; Wu, Xinyuan; Chen, Jingyu; Li, Jindu; Shi, Binglin; Zhang, Jie; Xiang, Bangde

Correlation of bone age development with overweight and obesity in 23,305 children from Beijing

北京23305名儿童骨龄发育与超重和肥胖的相关性研究

期刊:Endocrine

影响因子:2.9

doi:10.1007/s12020-024-03988-w

Zhou, Bo; Qu, Xia; Li, Minjun; Wang, Xi; Xu, Qi; Wang, Jianhong; Liu, Xiaoli; Zhang, Lili; Zhang, Ting; Gu, Jialu; Zhou, Lijun; Peng, Nan; Niu, Wenquan; Wang, Lin

Structure-Based Development of Ultra-Broad-Spectrum 3C-Like Protease Inhibitors

基于结构的超广谱3C样蛋白酶抑制剂的开发

Palmitic acid activates c-Myc via dual palmitoylation-dependent pathways to promote colon cancer

棕榈酸通过双重棕榈酰化依赖性途径激活c-Myc，从而促进结肠癌的发生。

Efficacy and safety of tyrosine kinase inhibitors in advanced hepatocellular carcinoma patients with Child-Pugh A and B cirrhosis: a meta-analysis

酪氨酸激酶抑制剂治疗伴有Child-Pugh A级和B级肝硬化的晚期肝细胞癌患者的疗效和安全性：一项荟萃分析

De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS.

通过靶向 cGAS 的变构位点，从头设计蛋白质缩合抑制剂

Structure-based design of potent and selective inhibitors targeting RIPK3 for eliminating on-target toxicity in vitro.

基于结构的高效选择性RIPK3抑制剂设计，可消除体外靶向毒性

Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease

猴痘病毒I7L蛋白酶的动态帽介导底物进入和强效抑制剂设计

The crystal structure of GH57 family amylopullulanase reveals its dual binding pockets sharing the same catalytic dyad

GH57家族淀粉支链酶的晶体结构揭示了其两个结合口袋共享同一个催化二元体。

Novel starting points for fragment-based drug design against human heat-shock protein 90 identified using crystallographic fragment screening

利用晶体学片段筛选鉴定出针对人热休克蛋白90的基于片段的药物设计的新起始点

ARID3A Promotes Tumor Progression by Activating TNF-α/NF-κB Signaling in Dual-Phenotype Hepatocellular Carcinoma

ARID3A通过激活TNF-α/NF-κB信号通路促进双表型肝细胞癌的肿瘤进展

Correlation of bone age development with overweight and obesity in 23,305 children from Beijing

北京23305名儿童骨龄发育与超重和肥胖的相关性研究