日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

3-Chlorodiphenylamine activates cardiac troponin by a mechanism distinct from bepridil or TFP

3-氯二苯胺激活心肌肌钙蛋白的机制与苄普地尔或TFP不同。

Tikunova, Svetlana B; Cuesta, Andres; Price, Morgan; Li, Monica X; Belevych, Natalya; Biesiadecki, Brandon J; Reiser, Peter J; Hwang, Peter M; Davis, Jonathan P

The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C

钙敏化剂药物MCI-154与心肌肌钙蛋白C的结构C端结构域结合。

Li, Monica X; Gelozia, Shorena; Danmaliki, Gaddafi I; Wen, Yurong; Liu, Philip B; Lemieux, M Joanne; West, Frederick G; Sykes, Brian D; Hwang, Peter M

Structures reveal details of small molecule binding to cardiac troponin

结构揭示了小分子与心肌肌钙蛋白结合的细节

Cai, Fangze; Li, Monica X; Pineda-Sanabria, Sandra E; Gelozia, Shorena; Lindert, Steffen; West, Frederick; Sykes, Brian D; Hwang, Peter M

The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29Q.

家族性肥厚型心肌病相关心肌肌钙蛋白 C 突变 L29Q 的结构和功能影响

Robertson Ian M, Sevrieva Ivanka, Li Monica X, Irving Malcolm, Sun Yin-Biao, Sykes Brian D

Computer-aided drug discovery approach finds calcium sensitizer of cardiac troponin

计算机辅助药物发现方法找到了心肌肌钙蛋白的钙敏化剂

Lindert, Steffen; Li, Monica X; Sykes, Brian D; McCammon, J Andrew

Structural and functional consequences of the cardiac troponin C L48Q Ca(2+)-sensitizing mutation

心肌肌钙蛋白C L48Q Ca(2+) 敏感突变的结构和功能后果

Wang, Dan; Robertson, Ian M; Li, Monica X; McCully, Michelle E; Crane, Melissa L; Luo, Zhaoxiong; Tu, An-Yue; Daggett, Valerie; Sykes, Brian D; Regnier, Michael

Solution structure of the regulatory domain of human cardiac troponin C in complex with the switch region of cardiac troponin I and W7: the basis of W7 as an inhibitor of cardiac muscle contraction

人源心肌肌钙蛋白C调节域与心肌肌钙蛋白I和W7的复合物的溶液结构:W7作为心肌收缩抑制剂的基础

Oleszczuk, Marta; Robertson, Ian M; Li, Monica X; Sykes, Brian D

Interaction of cardiac troponin with cardiotonic drugs: a structural perspective

心肌肌钙蛋白与强心药物的相互作用:结构视角

Li, Monica X; Robertson, Ian M; Sykes, Brian D