Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming

植物倍半萜内酯 DET 和 DETD-35 通过 GPX4 抑制和代谢重编程诱导对维莫非尼敏感和耐药的黑色素瘤发生铁死亡