日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

RNase1-driven ALK-activation is an oncogenic driver and therapeutic target in non-small cell lung cancer

RNase1驱动的ALK激活是非小细胞肺癌的致癌驱动因素和治疗靶点。

期刊:Signal Transduction and Targeted Therapy
影响因子:40.8
doi:10.1038/s41392-025-02206-x
Zhengyu Zha # ，Chunxiao Liu # ，Meisi Yan # ，Cong Chen # ，Cheng Yu ，Yaohui Chen ，Chenhao Zhou ，Lu Li ，Yi-Chuan Li ，Hiro Yamaguchi ，Leiguang Ye ，Tong Liu ，Ying-Nai Wang ，Heng-Huan Lee ，Wen-Hao Yang ，Li-Chuan Chan ，Baozhen Ke ，Jennifer L Hsu ，Lieming Ding ，Dong Ji ，Peng Pan ，Yiran Meng ，Yue Pu ，Lunxu Liu ，Mien-Chie Hung
肺癌
细胞生物学
肿瘤
ALK
肿瘤免疫
发表日期：2025
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Reshaping the Tumor Microenvironment of KRASG12D Pancreatic Ductal Adenocarcinoma with Combined SOS1 and MEK Inhibition for Improved Immunotherapy Response

联合抑制 SOS1 和 MEK 重塑 KRASG12D 胰腺导管腺癌的肿瘤微环境，以改善免疫治疗反应

期刊:Cancer Research Communications
影响因子:2
doi:10.1158/2767-9764.CRC-24-0172
Robert J Norgard #, Pratha Budhani #, Sarah A O'Brien #, Youli Xia, Jessica N Egan, Brianna Flynn, Joshua R Tagore, Joseph Seco, Gregory W Peet, Ania Mikucka, Ruby Wasti, Li-Chuan Chan, Melanie Hinkel, Sandra Martinez-Morilla, Jeanine Pignatelli, Francesca Trapani, Emily Corse, Di Feng, Kaja Kostyrk
代谢
肿瘤
胰腺癌
发表日期：2024
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Ribonuclease 1 Enhances Antitumor Immunity against Breast Cancer by Boosting T cell Activation

核糖核酸酶1通过增强T细胞活化来增强抗乳腺癌的抗肿瘤免疫力

期刊:International Journal of Biological Sciences
影响因子:8.2
doi:10.7150/ijbs.84592
Ying-Nai Wang ，Heng-Huan Lee ，Zhou Jiang ，Li-Chuan Chan ，Gabriel N Hortobagyi ，Dihua Yu ，Mien-Chie Hung
免疫/内分泌
T细胞
肿瘤免疫
细胞生物学
肿瘤
T细胞
乳腺癌
发表日期：2023
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Inhibition of Galectin-9 sensitizes tumors to anthracycline treatment via inducing antitumor immunity

抑制半乳糖凝集素-9可通过诱导抗肿瘤免疫使肿瘤对蒽环类药物治疗更加敏感。

期刊:International Journal of Biological Sciences
影响因子:8.2
doi:10.7150/ijbs.84108
Xian Sun,Wei-Jan Wang,Jilu Lang,Riyao Yang,Wan-Jou Shen,Linlin Sun,Jung-Mao Hsu,Li-Chuan Chan,Chia-Wei Li,Weiya Xia,Baozhen Ke,Guodong Yao,Kebin Huang,Pei-Chih Lee,Paul B Koller,Mien-Chie Hung
肿瘤
免疫/内分泌
肿瘤免疫
发表日期：2023
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Targeting the ALK-CDK9-Tyr19 kinase cascade sensitizes ovarian and breast tumors to PARP inhibition via destabilization of the P-TEFb complex

靶向 ALK-CDK9-Tyr19 激酶级联可通过破坏 P-TEFb 复合物的稳定性，增强卵巢和乳腺肿瘤对 PARP 抑制的敏感性

期刊:Nature Cancer
影响因子:23.5
doi:10.1038/s43018-022-00438-2
Yu-Yi Chu, Mei-Kuang Chen, Yongkun Wei, Heng-Huan Lee, Weiya Xia, Ying-Nai Wang, Clinton Yam, Jennifer L Hsu, Hung-Ling Wang, Wei-Chao Chang, Hirohito Yamaguchi, Zhou Jiang, Chunxiao Liu, Ching-Fei Li, Lei Nie, Li-Chuan Chan, Yuan Gao, Shao-Chun Wang, Jinsong Liu, Shannon N Westin, Sanghoon Lee, Ani
肿瘤
乳腺癌
FCM
IF
IHC-P
WB
CTIP
发表日期：2022
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Phosphorylation and Stabilization of PD-L1 by CK2 Suppresses Dendritic Cell Function

CK2介导的PD-L1磷酸化和稳定作用抑制树突状细胞功能

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-21-2300
Xixi Zhao # ，Yongkun Wei # ，Yu-Yi Chu ，Yintao Li ，Jung-Mao Hsu ，Zhou Jiang ，Chunxiao Liu ，Jennifer L Hsu ，Wei-Chao Chang ，Riyao Yang ，Li-Chuan Chan ，Jingkun Qu ，Shuqun Zhang ，Haoqiang Ying ，Dihua Yu ，Mien-Chie Hung
树突状细胞
PD-L1
树突状细胞
细胞生物学
信号转导
磷酸化
免疫/内分泌
发表日期：2022
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Fabrication of Gelatin Nanofibers by Electrospinning-Mixture of Gelatin and Polyvinyl Alcohol

静电纺丝法制备明胶纳米纤维——明胶与聚乙烯醇的混合物

期刊:Polymers
影响因子:4.9
doi:10.3390/polym14132610
Chi, Hsiu Yu; Chang, Nai Yun; Li, Chuan; Chan, Vincent; Hsieh, Jang Hsin; Tsai, Ya-Hui; Lin, Tingchao
发表日期：2022
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Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer

Ephrin受体A10单克隆抗体及其衍生的嵌合抗原受体T细胞在三阴性乳腺癌小鼠模型中发挥抗肿瘤作用

期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1016/j.jbc.2022.101817
Jong-Ho Cha ，Li-Chuan Chan ，Ying-Nai Wang ，Yu-Yi Chu ，Chie-Hong Wang ，Heng-Huan Lee ，Weiya Xia ，Woei-Cherng Shyu ，Shih-Ping Liu ，Jun Yao ，Chiung-Wen Chang ，Fan-Ru Cheng ，Jielin Liu ，Seung-Oe Lim ，Jennifer L Hsu ，Wen-Hao Yang ，Gabriel N Hortobagyi ，Chunru Lin ，Liuqing Yang ，Dihua Yu ，Long-Bin Jeng ，Mien-Chie Hung
单克隆抗体
乳腺癌
细胞生物学
信号转导
肿瘤
T细胞
免疫/内分泌
肿瘤免疫
T细胞
发表日期：2022
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Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation

人核糖核酸酶1作为Ephrin A4受体的分泌配体，可诱导乳腺肿瘤的发生。

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-021-23075-2
Heng-Huan Lee # ，Ying-Nai Wang # ，Wen-Hao Yang # ，Weiya Xia ，Yongkun Wei ，Li-Chuan Chan ，Yu-Han Wang ，Zhou Jiang ，Shouping Xu ，Jun Yao ，Yufan Qiu ，Yi-Hsin Hsu ，Wei-Lun Hwang ，Meisi Yan ，Jong-Ho Cha ，Jennifer L Hsu ，Jia Shen ，Yuanqing Ye ，Xifeng Wu ，Ming-Feng Hou ，Lin-Ming Tseng ，Shao-Chun Wang ，Mei-Ren Pan ，Chin-Hua Yang ，Yuan-Liang Wang ，Hirohito Yamaguchi ，Da Pang ，Gabriel N Hortobagyi ，Dihua Yu ，Mien-Chie Hung
Human
信号转导
肿瘤
肿瘤免疫
发表日期：2021
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TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis

TYRO3通过限制先天免疫和肿瘤铁死亡诱导抗PD-1/PD-L1疗法耐药。

期刊:Journal of Clinical Investigation
影响因子:13.3
doi:10.1172/JCI139434
Zhou Jiang ，Seung-Oe Lim ，Meisi Yan ，Jennifer L Hsu ，Jun Yao ，Yongkun Wei ，Shih-Shin Chang ，Hirohito Yamaguchi ，Heng-Huan Lee ，Baozhen Ke ，Jung-Mao Hsu ，Li-Chuan Chan ，Gabriel N Hortobagyi ，Liuqing Yang ，Chunru Lin ，Dihua Yu ，Mien-Chie Hung
免疫/内分泌
PD-L1
肿瘤免疫
铁死亡
PD-1
肿瘤
发表日期：2021
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