日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Efficacy and safety of low-dose interleukin 2 for Behçet's syndrome: a randomized, placebo-controlled, double-blind, phase 2 clinical trial

低剂量白细胞介素 2 治疗白塞氏病的疗效和安全性：一项随机、安慰剂对照、双盲 II 期临床试验

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-68100-w
Liu, Tian; Zhou, Wenyan; Zhu, Yan; Xia, Weiyi; Chen, Jiali; Xiao, Xian; Huang, Bo; Feng, Ruiling; Ye, Hua; Chen, Shi; Zhang, Xiaoying; Shao, Miao; Li, Chun; Jia, Yuan; Miao, Miao; Jin, Yuebo; Li, Xue; Zhang, Xia; Zhou, Yunshan; Li, Ru; Zhang, Xuewu; Su, Yin; Liu, Huixin; Li, Jing; Hu, Fanlei; Guo, Jianping; Sun, Xiaolin; He, Jing; Li, Zhanguo
细胞生物学
发表日期：2026
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scVMAP: a comprehensive platform for integrating single-cell chromatin accessibility regions with causal variants

scVMAP：一个将单细胞染色质可及区域与致病变异整合的综合平台

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf1112
Yu, Zheng-Min; Qian, Feng-Cui; Fang, Qiao-Li; Meng, Xiang-Yang; Li, Yan-Yu; Feng, Chen-Chen; Li, Li-Dong; Li, Bing-Long; Feng, Yu-Rong; Jiang, Hui; Wang, Qiu-Yu; Fan, Xuan; Guo, Jin-Cheng; Li, Chun-Quan
细胞生物学
单细胞
发表日期：2026
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Mutant p53 epigenetically rewires CXCL10 to promote CD8⁺ T-cell infiltration and enhance the anti-PD-1 response in advanced prostate cancer

突变型p53通过表观遗传机制重塑CXCL10，促进CD8⁺ T细胞浸润，并增强晚期前列腺癌中的抗PD-1反应。

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-026-03672-z
Chen, Jia; Ge, Qintao; He, Jun; Bian, Zichen; Yu, Haoming; Li, Chun; Meng, Jialin; Yin, Shuiping; Hao, Zongyao; Liang, Chaozhao; Zhang, Meng
肿瘤
表观遗传
T细胞
肿瘤免疫
CXCL1
CD8
CXCL10
T细胞
细胞生物学
前列腺癌
PD-1
免疫/内分泌
发表日期：2026
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Dynamic chromatin regulatory programs of sucrose and citric acid metabolism during fruit ripening in Citrus.

柑橘果实成熟过程中蔗糖和柠檬酸代谢的动态染色质调控程序。

期刊:Plant Cell
影响因子:11.6
doi:10.1093/plcell/koag060
Song Xin, Wang Ting-Ting, Zhao Peng, He Li-Gang, Fan Yan-Jie, Zhang Yu, Liu Ting, Shi Chun-Mei, Jiang Ying-Chun, Tan Feng-Quan, Bendahmane Abdelhafid, Li Chun-Long, Wu Li-Ming, Song Fang
代谢
发表日期：2026
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Dusp15 modulates mtHsp70 Thr116 phosphorylation state to preserve mito-UPR and attenuate cardiac dysfunction in diabetic cardiomyopathy

Dusp15通过调节mtHsp70 Thr116的磷酸化状态来维持线粒体UPR，从而减轻糖尿病心肌病中的心脏功能障碍。

期刊:Cardiovascular Diabetology
影响因子:10.6
doi:10.1186/s12933-026-03125-z
Liu, Yan; Shi, Hongshuo; Li, Chun; Zhuang, Haowen; Li, Yinglong; He, Xiuling; Jiang, Ying; Jin, Zhiyu; Guo, Zhijiang; Ong, Sangbing; Wang, Yuanyuan; Chang, Xing; An, Guipeng; Wang, Junyan
心肌病
信号转导
心血管
代谢
线粒体
糖尿病
磷酸化
发表日期：2026
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Computer-Assisted Colonoscopy in High-Adenoma Detection Rate Settings in a High-Risk Population: A Randomized Clinical Trial

在腺瘤检出率高的高危人群中应用计算机辅助结肠镜检查：一项随机临床试验

期刊:Jama Network Open
影响因子:9.7
doi:10.1001/jamanetworkopen.2026.4881
Hsu, Wen-Feng; Kuo, Chen-Ya; Yen, Hsu-Heng; Lin, Yu-Min; Chen, Yen-Nien; Sun, Cheuk-Kay; Chang, Wei-Yuan; Lin, Hsuan-Ho; Wu, Hao-Yu; Chang, Li-Chun; Chang, Chi-Yang; Wu, Ming-Shiang; Chiu, Han-Mo
发表日期：2026
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Combination antiviral and anti-inflammatory therapy mitigates persistent neurological deficits in mice post SARS-CoV-2 infection

抗病毒和抗炎联合疗法可减轻小鼠SARS-CoV-2感染后的持续性神经功能缺损

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2530209123
Verma, Abhishek Kumar; Tan, Lu; Schuster, Noah; Moye, Skyler L; Lin, Li-Chun; Lowery, Shea; Duraisami, Eazhisaivallabi; Lloréns, Juan E Abrahante; Qiu, Qiang; Hefti, Marco; Meyerholz, David K; Coleman, Mitchell C; Yu, C Ron; Albers, Mark W; Perlman, Stanley
炎症/感染
SARS-CoV-2
微生物学
发表日期：2026
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Betaine-homocysteine methyltransferase protects against acetaminophen-induced acute liver failure via BACH1-SCD1-oleic acid axis.

甜菜碱-同型半胱氨酸甲基转移酶通过 BACH1-SCD1-油酸轴保护机体免受对乙酰氨基酚引起的急性肝衰竭。

期刊:Acta Pharmacologica Sinica
影响因子:8.4
doi:10.1038/s41401-025-01622-7
Zhang Yu-Ting, Yang Xiao-Ming, Jin Quan-Shan, Chen Jia-Yi, Zhu Nan-Bin, Ju Yi, Lin Zi-Yan, Zhi Yang, Dong Yi-Nuo, Li Chun-Min, Mao Yi-Min, Zhi Xiu-Ling, Ma Ming-Yang, Xu Ya-Li, Li Xiao-Bo
肝衰竭
SCD
毒理研究
BACH1
发表日期：2026
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Regulation of DMSP organosulfur cycling in ubiquitous Roseobacter marine bacteria.

普遍存在的海洋细菌玫瑰杆菌中DMSP有机硫循环的调控。

期刊:EMBO Journal
影响因子:8.3
doi:10.1038/s44318-026-00706-2
Fu Hui-Hui, Wang Ming-Chen, Wang Zhi-Qing, Sang Yu-Han, Li Zhen-Kun, Li Fei-Fei, Liu Jia-Rong, Qin Qi-Long, Zhu Xiao-Yu, Wang Na, Wan Jin-Jian, Teng Zhao-Jie, Zhang Wei-Peng, Gates Andrew J, Li Chun-Yang, Todd Jonathan D, Zhang Yu-Zhong
微生物学
信号转导
多发性硬化症
发表日期：2026
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Pharmacological Inhibition of APT2 by Solasonine Promotes Ferroptosis Through Palmitoylation Modulation in Gallbladder Cancer

茄碱通过棕榈酰化调控促进胆囊癌中APT2的药理学抑制，进而促进铁死亡

期刊:Phytotherapy Research
影响因子:6.3
doi:10.1002/ptr.70245
Shi, Liu-Qing; Zhao, Jing-Wei; Zhu, Jia-Yun; Zhao, Cheng; Yang, Zi-Yi; Pan, Li-Jia; Ma, Ben; Chen, Zheng-Yu; Wang, Zi-Ying; Li, Chun-Jie; Liu, Shi-Lei; Mei, Jia-Wei; Dong, Ping
肿瘤
肿瘤免疫
信号转导
铁死亡
胆囊癌
发表日期：2026
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