日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An Ensemble Learning Artificial Intelligence Model for Alzheimer's Disease Detection Using OCT

基于光学相干断层扫描的阿尔茨海默病检测集成学习人工智能模型

Ran, An Ran; Hu, Xiaoyan; Hui, Herbert Y H; Dai, Jiajia; Chan, Victor T T; Ho, Ko; Au, Lisa W C; Ng, Chak Fung; Sham, Kaiser; Zheng, Chunwen; Liu, Xujia; He, Qinghua; Tham, Clement C; Kwok, Timothy C K; Hilal, Saima; Cheng, Ching-Yu; Chua, Jacqueline; Schmetterer, Leopold; Liu, T Y Alvin; Tham, Yih Chung; Li-Hsian Chen, Christopher; Wong, Tien Yin; Mok, Vincent C T; Cheung, Carol Y

The AHA/ASA and DSM-V diagnostic criteria for vascular cognitive impairment identify cases with predominant vascular pathology

AHA/ASA 和 DSM-V 血管性认知障碍诊断标准可识别以血管病变为主的病例

Folloso, Melmar C; Villaraza, Steven G; Yi-Wen, Lo; Pek-Lan, Khong; Tanaka, Tomotaka; Hilal, Saima; Venketasubramanian, Narayanaswamy; Li-Hsian Chen, Christopher

Time-restricted feeding modulates the DNA methylation landscape, attenuates hallmark neuropathology and cognitive impairment in a mouse model of vascular dementia

限时喂养可调节 DNA 甲基化状况,减轻血管性痴呆小鼠模型中的标志性神经病理学和认知障碍

Sharmelee Selvaraji, Motakis Efthymios, Roger Sik Yin Foo, David Y Fann, Mitchell Kim Peng Lai, Christopher Li Hsian Chen, Kah Leong Lim, Thiruma V Arumugam

Intermittent Fasting Attenuates Hallmark Vascular and Neuronal Pathologies in a Mouse Model of Vascular Cognitive Impairment

间歇性禁食可减轻血管性认知障碍小鼠模型中的标志性血管和神经元病理

Vismitha Rajeev, David Y Fann, Quynh Nhu Dinh, Hyun Ah Kim, T Michael De Silva, Dong-Gyu Jo, Grant R Drummond, Christopher G Sobey, Mitchell K P Lai, Christopher Li-Hsian Chen, Thiruma V Arumugam

Truncated Tau caused by intron retention is enriched in Alzheimer's disease cortex and exhibits altered biochemical properties

内含子保留导致的截短 Tau 在阿尔茨海默病皮层中富集,并表现出改变的生化特性

Zhen-Kai Ngian, Yow-Yong Tan, Ching-Thong Choo, Wei-Qi Lin, Chao-Yong Leow, Shan-Jie Mah, Mitchell Kim-Peng Lai, Christopher Li-Hsian Chen, Chin-Tong Ong

AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia

AIM2 炎症小体介导血管性痴呆小鼠模型中的标志性神经病理学改变和认知障碍

Luting Poh, David Y Fann, Peiyan Wong, Hong Meng Lim, Sok Lin Foo, Sung-Wook Kang, Vismitha Rajeev, Sharmelee Selvaraji, Vinaya Rajagopal Iyer, Nageiswari Parathy, Mohammad Badruzzaman Khan, David C Hess, Dong-Gyu Jo, Grant R Drummond, Christopher G Sobey, Mitchell K P Lai, Christopher Li-Hsian Chen

Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging

海马转录组分析揭示慢性灌注不足和衰老中的常见疾病途径

Sang-Ha Baik, Sharmelee Selvaraji, David Y Fann, Luting Poh, Dong-Gyu Jo, Deron R Herr, Shenpeng R Zhang, Hyun Ah Kim, Michael De Silva, Mitchell K P Lai, Christopher Li-Hsian Chen, Grant R Drummond, Kah-Leong Lim, Christopher G Sobey, Thiruma V Arumugam