Chidamide increases the sensitivity of refractory or relapsed acute myeloid leukemia cells to anthracyclines via regulation of the HDAC3 -AKT-P21-CDK2 signaling pathway
西达本胺通过调控HDAC3-AKT-P21-CDK2信号通路增加难治性或复发性急性髓系白血病细胞对蒽环类药物的敏感性
期刊:Journal of Experimental & Clinical Cancer Research
影响因子:11.4
doi:10.1186/s13046-020-01792-8
Hao Wang, Yu-Chen Liu, Cheng-Ying Zhu, Fei Yan, Meng-Zhen Wang, Xiao-Su Chen, Xiao-Kai Wang, Bao-Xu Pang, Yong-Hui Li, Dai-Hong Liu, Chun-Ji Gao, Shu-Jun Liu, Li-Ping Dou
信号转导
肿瘤
白血病
其它细胞
FCM
IF
IHC-P
WB
PI3K/Akt
