日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer

一项评估瑞法替尼联合索拉非尼治疗晚期癌症患者的安全性、药代动力学和药效学的I期研究

Adjei, Alex A; Richards, Donald A; El-Khoueiry, Anthony; Braiteh, Fadi; Becerra, Carlos H R; Stephenson, Joe J Jr; Hezel, Aram F; Sherman, Morris; Garbo, Lawrence; Leffingwell, Diane P; Iverson, Cory; Miner, Jeffrey N; Shen, Zancong; Yeh, Li-Tain; Gunawan, Sonny; Wilson, David M; Manhard, Kimberly J; Rajagopalan, Prabhu; Krissel, Heiko; Clendeninn, Neil J

Erratum to: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney

更正:雷西那德是一种新型口服痛风化合物,其作用机制是通过抑制肾脏中的尿酸转运蛋白来降低血清尿酸水平。

Miner, Jeffrey N; Tan, Philip K; Hyndman, David; Liu, Sha; Iverson, Cory; Nanavati, Payal; Hagerty, David T; Manhard, Kimberly; Shen, Zancong; Girardet, Jean-Luc; Yeh, Li-Tain; Terkeltaub, Robert; Quart, Barry

Pharmacokinetics, pharmacodynamics, and safety of lesinurad, a selective uric acid reabsorption inhibitor, in healthy adult males

雷西纳德(一种选择性尿酸重吸收抑制剂)在健康成年男性中的药代动力学、药效学和安全性

Shen, Zancong; Rowlings, Colin; Kerr, Brad; Hingorani, Vijay; Manhard, Kimberly; Quart, Barry; Yeh, Li-Tain; Storgard, Chris

A novel nonnucleoside analogue that inhibits human immunodeficiency virus type 1 isolates resistant to current nonnucleoside reverse transcriptase inhibitors

一种新型非核苷类类似物,可抑制对现有非核苷类逆转录酶抑制剂耐药的人类免疫缺陷病毒1型分离株

Zhang, Zhijun; Xu, Wen; Koh, Yung-Hyo; Shim, Jae Hoon; Girardet, Jean-Luc; Yeh, Li-Tain; Hamatake, Robert K; Hong, Zhi

Metabolic activation of pradefovir by CYP3A4 and its potential as an inhibitor or inducer.

CYP3A4 对普拉地福韦的代谢活化及其作为抑制剂或诱导剂的潜力

Lin Chin-chung, Fang Che, Benetton Salete, Xu Gui-fen, Yeh Li-Tain