日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Safety and tolerability of oral vorolanib for neovascular (wet) age-related macular degeneration: a phase I, open-label study

口服沃罗拉尼治疗新生血管性（湿性）年龄相关性黄斑变性的安全性和耐受性：一项 I 期开放标签研究

期刊:
影响因子:
doi:10.1038/s41433-023-02496-x
Gao, Yunxia; Lu, Fang; Li, Xiaoxin; Dai, Hong; Liu, Kun; Liu, Xiaoling; Sun, Zuhua; Xiang, Jin; Ding, Lieming; Liang, Chris; Wang, Yang; Shen, Zhilin; Zhang, Ming
发表日期：2023
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Phase 1b trial of anti-VEGF/PDGFR vorolanib combined with immune checkpoint inhibitors in patients with advanced solid tumors

抗 VEGF/PDGFR 药物 vorolanib 联合免疫检查点抑制剂治疗晚期实体瘤患者的 1b 期试验

期刊:Cancer Chemotherapy and Pharmacology
影响因子:2.3
doi:10.1007/s00280-022-04406-6
Bagegni, Nusayba A; Park, Haeseong; Kraft, Katlyn; O-Toole, Maura; Gao, Feng; Waqar, Saiama N; Ratner, Lee; Morgensztern, Daniel; Devarakonda, Siddhartha; Amin, Manik; Baggstrom, Maria Q; Liang, Chris; Selvaggi, Giovanni; Wang-Gillam, Andrea
VEGF
EGF
免疫/内分泌
发表日期：2022
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Ensartinib vs Crizotinib for Patients With Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer: A Randomized Clinical Trial

恩沙替尼与克唑替尼治疗间变性淋巴瘤激酶阳性非小细胞肺癌患者的随机临床试验

期刊:Jama Oncology
影响因子:20.1
doi:10.1001/jamaoncol.2021.3523
Horn, Leora; Wang, Ziping; Wu, Gang; Poddubskaya, Elena; Mok, Tony; Reck, Martin; Wakelee, Heather; Chiappori, Alberto A; Lee, Dae Ho; Breder, Valeriy; Orlov, Sergey; Cicin, Irfan; Cheng, Ying; Liu, Yunpeng; Fan, Yun; Whisenant, Jennifer G; Zhou, Yi; Oertel, Vance; Harrow, Kim; Liang, Chris; Mao, Li; Selvaggi, Giovanni; Wu, Yi-Long
肺癌
肿瘤
肿瘤免疫
信号转导
淋巴瘤
细胞生物学
发表日期：2021
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Vorolanib, an oral VEGFR/PDGFR dual tyrosine kinase inhibitor for treatment of patients with advanced solid tumors: An open-label, phase I dose escalation and dose expansion trial

Vorolanib，一种口服的VEGFR/PDGFR双重酪氨酸激酶抑制剂，用于治疗晚期实体瘤患者：一项开放标签的I期剂量递增和剂量扩展试验

期刊:Chinese Journal of Cancer Research
影响因子:6.3
doi:10.21147/j.issn.1000-9604.2021.01.11
Song, Yan; Wang, Jinwan; Ren, Xiubao; Jin, Jie; Mao, Li; Liang, Chris; Ding, Lieming; Yang, Lin
信号转导
VEGF
EGF
EGFR
发表日期：2021
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Interaction of small molecules with the SARS-CoV-2 main protease in silico and in vitro validation of potential lead compounds using an enzyme-linked immunosorbent assay

使用酶联免疫吸附试验进行小分子与 SARS-CoV-2 主蛋白酶的计算机相互作用以及潜在先导化合物的体外验证

期刊:Computational Biology and Chemistry
影响因子:2.6
doi:10.1016/j.compbiolchem.2020.107408
Eleni Pitsillou, Julia Liang, Chris Karagiannis, Katherine Ververis, Kevion K Darmawan, Ken Ng, Andrew Hung, Tom C Karagiannis
免疫
新冠
发表日期：2020
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Monitoring Therapeutic Response and Resistance: Analysis of Circulating Tumor DNA in Patients With ALK+ Lung Cancer

监测治疗反应和耐药性：ALK阳性肺癌患者循环肿瘤DNA的分析

期刊:Journal of Thoracic Oncology
影响因子:20.8
doi:10.1016/j.jtho.2019.08.003
Horn, Leora; Whisenant, Jennifer G; Wakelee, Heather; Reckamp, Karen L; Qiao, Huan; Leal, Ticiana A; Du, Liping; Hernandez, Jennifer; Huang, Vincent; Blumenschein, George R; Waqar, Saiama N; Patel, Sandip P; Nieva, Jorge; Oxnard, Geoffrey R; Sanborn, Rachel E; Shaffer, Tristan; Garg, Kavita; Holzhausen, Allison; Harrow, Kimberly; Liang, Chris; Lim, Lee P; Li, Mark; Lovly, Christine M
肺癌
肿瘤
肿瘤免疫
ALK
发表日期：2019
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Phase I, First-in-Human, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Vorolanib in Patients with Advanced Solid Tumors

一项评估沃罗拉尼在晚期实体瘤患者中安全性、耐受性和药代动力学的I期、首次人体剂量递增研究

期刊:Oncologist
影响因子:4.2
doi:10.1634/theoncologist.2018-0740
Bendell, Johanna C; Patel, Manish R; Moore, Kathleen N; Chua, Cynthia C; Arkenau, Hendrik-Tobias; Dukart, Gary; Harrow, Kim; Liang, Chris
Human
发表日期：2019
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Ensartinib (X-396) in ALK-Positive Non-Small Cell Lung Cancer: Results from a First-in-Human Phase I/II, Multicenter Study

恩沙替尼（X-396）治疗ALK阳性非小细胞肺癌：一项首次人体I/II期多中心研究的结果

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-17-2398
Horn, Leora; Infante, Jeffrey R; Reckamp, Karen L; Blumenschein, George R; Leal, Ticiana A; Waqar, Saiama N; Gitlitz, Barbara J; Sanborn, Rachel E; Whisenant, Jennifer G; Du, Liping; Neal, Joel W; Gockerman, Jon P; Dukart, Gary; Harrow, Kimberly; Liang, Chris; Gibbons, James J; Holzhausen, Allison; Lovly, Christine M; Wakelee, Heather A
ALK
Human
细胞生物学
肿瘤
肿瘤免疫
肺癌
发表日期：2018
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Pharmacodynamic study using FLT PET/CT in advanced solid malignancies treated with a sequential combination of X-82 and docetaxel.

使用 FLT PET/CT 对采用 X-82 和多西他赛序贯联合治疗的晚期实体恶性肿瘤进行药效学研究

期刊:Cancer Chemotherapy and Pharmacology
影响因子:2.3
doi:10.1007/s00280-018-3599-3
Scarpelli Matthew, Rampurwala Murtuza, Eickhoff Jens, Carmichael Lakeesha, Heideman Jennifer, Binger Kimberly, Kolesar Jill, Perlman Scott, Harrow Kim, Dukart Gary, Liang Chris, Jeraj Robert, Liu Glenn, Bruce Justine Yang
肿瘤
肿瘤免疫
发表日期：2018
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Oral Tyrosine Kinase Inhibitor for Neovascular Age-Related Macular Degeneration: A Phase 1 Dose-Escalation Study

口服酪氨酸激酶抑制剂治疗新生血管性年龄相关性黄斑变性：一项 I 期剂量递增研究

期刊:Jama Ophthalmology
影响因子:9.2
doi:10.1001/jamaophthalmol.2017.1571
Jackson, Timothy L; Boyer, David; Brown, David M; Chaudhry, Nauman; Elman, Michael; Liang, Chris; O'Shaughnessy, Denis; Parsons, Edward C; Patel, Sunil; Slakter, Jason S; Rosenfeld, Philip J
信号转导
发表日期：2017
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