日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Efficacy and safety of hetrombopag, a novel thrombopoietin receptor agonist, in children and adolescents with immune thrombocytopenia: results from a randomized, multicenter, placebo-controlled phase 3 trial

一项随机、多中心、安慰剂对照的3期临床试验结果显示，新型血小板生成素受体激动剂海曲波帕治疗儿童和青少年免疫性血小板减少症的疗效和安全性

期刊:Journal of Hematology & Oncology
影响因子:40.4
doi:10.1186/s13045-026-01790-x
Wu, Runhui; Gao, Ju; Liu, Yufeng; Yu, Jie; Hu, Shaoyan; Liang, Hui; Jiang, Hui; Zhai, Xiaowen; Zhou, Min; Hao, Wenge; Mei, Heng; Li, Fei; Chen, Yumei; Liu, Wei; Yan, Mei; Li, Runzi; Xiong, Junye; Zhu, Zhenyi; Cheng, Xiaoling; Wang, Tianyou
血小板
信号转导
免疫/内分泌
发表日期：2026
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HSP70 Interactome-Mediated Proteolysis Targeting Chimera (HSP70-PROTAC) for Ferroptosis-Driven Cancer Treatment.

HSP70 相互作用组介导的蛋白水解靶向嵌合体 (HSP70-PROTAC) 用于铁死亡驱动的癌症治疗。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202513655
Dong Jinyun, Li Yulong, Liang Hui, Wu Zumei, Wang Shiqun, Wang Yichao, Xu Jieyu, Lan Yanning, Cai Maohua, Pan Guangzhao, Yang Haiyan, Miao Kai, Chen Zhe-Sheng, Tao Fangfang, Ma Xuelei, Qin Jiang-Jiang
肿瘤
SP7
HSP70
铁死亡
发表日期：2026
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Reduced glycoprotein hormone β5 links male aging and testosterone decline to increased adiposity.

糖蛋白激素β5的减少将男性衰老和睾酮下降与脂肪堆积增加联系起来。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI192355
Xiao Gengmiao, Qian Aijun, Gao Zhuo, Dai Tingting, Liang Hui, Wang Shuai, Deng Mulan, Yan Yunjing, Zhang Xindan, Zhang Xuedi, Mu Yunping, Wang Jiqiu, Gao Aibo, Zhang Huijie, Li Fanghong, Zhao Allan Zijian
衰老
免疫/内分泌
发表日期：2026
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TNFAIP6, an independent prognostic monitor and therapy target, promoted low-grade glioma recurrence and progression via JAK3-STAT6 signaling

TNFAIP6 是一种独立的预后监测指标和治疗靶点，它通过 JAK3-STAT6 信号通路促进低级别胶质瘤的复发和进展。

期刊:International Journal of Surgery
影响因子:10.1
doi:10.1097/JS9.0000000000003914
Kong, Jian; Xu, Shanling; Wang, Yuanlong; Hua, Shuhui; Gong, Hongyan; Dong, Rui; Wang, Jiahan; Lin, Yanan; Li, Chuan; Bi, Yanlin; Wang, Bin; Lin, Xu; Liang, Hui; Huang, Qinhong; Xian, Mingming; Chen, Taoliang; Sun, Xinlin
JAK3
AIP
JAK/STAT
信号转导
STAT6
胶质瘤
发表日期：2026
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FKBP10 promotes M2 polarization of macrophage via MEK/ERK/CXCL8 axis and facilitates tumor progression in clear cell renal cell carcinoma

FKBP10 通过 MEK/ERK/CXCL8 轴促进巨噬细胞 M2 极化，并促进透明细胞肾细胞癌的肿瘤进展。

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.117535
Chen, Jin-Wei; Li, Jia-Ying; Feng, Hao-Qian; Fu, Liang-Min; Zhou, Xin-Wei; Lin, Han-Sen; Wang, Ying-Han; Liu, Ke-Zhi; Chen, Yu-Hang; Wang, Zhu; Deng, Qiong; Wang, Jie-Yan; Jin, Mei-Yu; Liang, Hui; Wei, Jin-Huan; Luo, Jun-Hang; Gui, Cheng-Peng
巨噬细胞
肿瘤
肿瘤免疫
巨噬细胞
肾癌
MAPK/ERK
细胞生物学
CXCL8
免疫/内分泌
发表日期：2026
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Advances in cellular and molecular mechanisms of trauma-induced organ inflammation and dysfunction

创伤诱导的器官炎症和功能障碍的细胞和分子机制研究进展

期刊:Burns & Trauma
影响因子:9.6
doi:10.1093/burnst/tkaf074
Wang, Jieyan; Liang, Hui; Fan, Jie
炎症/感染
细胞生物学
炎症
发表日期：2026
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A Glycopeptide Mosaic Vaccine Elicits Robust Antitumor Immunity by Targeting Glycan Heterogeneity

一种糖肽嵌合疫苗通过靶向聚糖异质性诱导强大的抗肿瘤免疫

期刊:JACS Au
影响因子:8.7
doi:10.1021/jacsau.5c01389
Wu, Ye; Ma, Wenjing; Jiang, Yinyu; Ling, Yi; Zhou, Yang; Guo, Yajing; Hong, Sheng; Ding, Feiqing; Zhang, Jingfei; Li, Baosong; Liang, Hui; Wang, Zhu; Li, Yiliang; Li, Tiehai; Cai, Hui
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2026
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PAD4+ neutrophils promote hepatic stellate cell activation and accelerate MASH fibrosis progression viaNET-DNA/TAOK1/MAPK pathways

PAD4+中性粒细胞通过NET-DNA/TAOK1/MAPK通路促进肝星状细胞活化并加速MASH纤维化进展

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.191479
Shen, Jiajia; Huang, Shanshan; Wang, Yaohui; Wang, Qingyuan; Lin, Shibo; Guan, Wei; Gong, Yingyun; Si, Yiming; Zhao, Ming; Zhou, Hongwen; Liang, Hui
中性粒细胞
信号转导
MAPK/ERK
粒细胞
细胞生物学
发表日期：2026
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Niacin Mitigates Cyclophosphamide-Induced Immunosuppression by Maintaining Intestinal Homeostasis and Regulating the HCAR2/NLRP3 and PTGS2/PGE2 Signaling Pathways

烟酸通过维持肠道稳态和调节HCAR2/NLRP3和PTGS2/PGE2信号通路来减轻环磷酰胺诱导的免疫抑制

期刊:Nutrients
影响因子:5
doi:10.3390/nu18050744
Bai, Yixian; Zhou, Yifan; Wang, Guifa; Wang, Yuanzheng; Li, Tongtong; Zhang, Kening; Zhang, Huaqi; Liang, Hui
信号转导
HCAR2
LRP3
NLRP3
免疫/内分泌
发表日期：2026
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TNFAIP6, an independent prognostic monitor and therapy target, promoted low-grade glioma recurrence and progression via JAK3-STAT6 signaling

TNFAIP6 是一种独立的预后监测指标和治疗靶点，它通过 JAK3-STAT6 信号通路促进低级别胶质瘤的复发和进展。

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2026.1752954
Chen, Si-Jie; Tang, Tao-Tao; Xie, Li-Jun; Wang, Bo; Di, Yan; Wu, Min; Li, Zuo-Lin; Wen, Yi; Lv, Lin-Li; Tang, Ri-Ning; Wang, Bin; Liu, Bi-Cheng; Liang, Hui; Huang, Qinhong; Xian, Mingming; Chen, Taoliang; Sun, Xinlin
信号转导
AIP
STAT6
JAK/STAT
JAK3
胶质瘤
发表日期：2026
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