BRCA1 safeguards genome integrity by activating chromosome asynapsis checkpoint to eliminate recombination-defective oocytes.
BRCA1 通过激活染色体联会异常检查点来消除重组缺陷的卵母细胞,从而保护基因组的完整性
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2401386121
Bai Long, Li Peng, Xiang Yu, Jiao Xiaofei, Chen Jiyuan, Song Licun, Liang Zhongyang, Liu Yidan, Zhu Yimin, Lu Lin-Yu