日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

First-line Aumolertinib (EGFR tyrosine kinase inhibitor) plus apatinib (VEGFR inhibitor) versus aumolertinib in EGFR-mutant non-small cell lung cancer patients: a randomized, multicenter, phase II trial

一线治疗EGFR突变型非小细胞肺癌患者，比较奥莫替尼（EGFR酪氨酸激酶抑制剂）联合阿帕替尼（VEGFR抑制剂）与奥莫替尼单药治疗的疗效：一项随机、多中心、II期临床试验

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02550-y
Zhang, Fan; Zheng, Zhendong; Zhang, Hongmei; Yan, Xiaolong; Liu, Zhefeng; Yang, Fan; Wen, Juyi; Gan, Xin; Wu, Lin; Cang, Shundong; Wang, Hongmei; Zhao, Jun; Peng, Liang; Li, Xiaosong; Fan, Zaiwen; Shen, Ge; Zhou, Qiong; Zou, Jinjing; Xu, Yu; Zhang, Lei; Zhao, Mingfang; Cai, Shangli; Hu, Yi
肺癌
肿瘤
肿瘤免疫
信号转导
EGF
EGFR
细胞生物学
VEGF
发表日期：2026
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Mechanoluminescent Aluminum Nitride Crystal for Super-Sensitive Optical Manometry, Thermometry and Force Sensing

用于超灵敏光学测压、测温和力传感的机械发光氮化铝晶体

期刊:Advanced Materials
影响因子:26.8
doi:10.1002/adma.202511943
Zheng, Teng; Woźny, Przemysław; Soler-Carracedo, Kevin; Han, Dongxue; Wang, Jie; Peng, Liang; Li, Wenliang; Peng, Dengfeng; Wu, Honglei; Moszczyński, Jan; Mahlik, Sebastian; Runowski, Marcin
发表日期：2026
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Sodium-Glucose Cotransporter 2 Inhibitors for Patients With Prostate Cancer Undergoing Hormone Therapy

接受激素治疗的前列腺癌患者可使用钠-葡萄糖协同转运蛋白2抑制剂

期刊:Jama Oncology
影响因子:20.1
doi:10.1001/jamaoncol.2025.5869
Shi, Ruofan; Zhan, Yongle; Ma, Ruochen; Ali, Salida; Yao, Chi; Chun, Tsun Tsun Stacia; Ng, Ada Tsui-Lin; Chiu, Matthew Kin-Liang; Li, Bryan Cho Wing; Na, Rong
肿瘤
前列腺癌
肿瘤免疫
免疫/内分泌
发表日期：2026
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Lactate derived from macrophages drives skin dermal fibroblasts phenotypic remodeling via MCT1-primed histone H3 lysine 23 lactylation in hypertrophic scar.

巨噬细胞产生的乳酸通过 MCT1 启动的组蛋白 H3 赖氨酸 23 乳酸化，驱动皮肤真皮成纤维细胞表型重塑，形成肥厚性瘢痕。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69388-y
Yuan Yixuan, Xiao Yujie, Zou Jie, Luo Liang, Li Mengyang, Shen Kuo, Wei Lai, Zhang Yihao, Wang Peng, Chen Yan, Zhuo Shixuan, Zhang Hao, Song Shijie, Jia Yanhui, Wang Kejia, Jiang Shiqing, Guan Hao, Hu Dahai
巨噬细胞
成纤维细胞
巨噬细胞
乳酸化
细胞生物学
免疫/内分泌
发表日期：2026
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Single-Chain Anti-IL-1β Antibody Carried by Outer Membrane Vesicles of Bacteroides fragilis Alleviates Tubular Inflammation in Chronic Kidney Disease.

由脆弱拟杆菌外膜囊泡携带的单链抗IL-1β抗体可减轻慢性肾脏病中的肾小管炎症。

期刊:Journal of Extracellular Vesicles
影响因子:14.5
doi:10.1002/jev2.70234
Li Liang, Li Xue Qi, Zhang Jia Xiu, Wu Qin Yi, Chen Pei Pei, Ruan Xiong Zhong, Ma Kun Ling
炎症/感染
IL-1β
Immunology/Inflammation
炎症
囊泡
发表日期：2026
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A Pan-TE Map Reveals the Important Role of Transposable Elements in Gene Expression and Phenotypic Diversity in 2,311 Rapeseed Accessions

泛转座子图谱揭示了转座子在2311份油菜种质资源的基因表达和表型多样性中的重要作用

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202512036
Yang, Zhiquan; Fan, Haiyan; Chen, Yifan; Li, Jiawei; Chen, Minjian; Tan, Yingying; Guo, Liang; Li, Jintao; Liu, Kede; Yang, Qing-Yong
发表日期：2026
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Hepatocyte-Derived Extracellular Vesicles Deliver miR-328-3p to Trigger PP2A-B56δ-Mediated p-NLRP3(S295)-Dependent Metaflammation in Macrophages upon Microcystin-LR Exposure

肝细胞来源的细胞外囊泡将 miR-328-3p 递送至巨噬细胞，触发 PP2A-B56δ 介导的 p-NLRP3(S295) 依赖性代谢炎症，以应对微囊藻毒素-LR 暴露

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202507039
Wu, Jia-Shen; Zhang, Xin-Yu; Ma, Xin-Yu; Wei, Yue-Yue; Wang, Lei-Lei; Du, Ze-Bang; Xia, Xiao-Gang; Che, Lin; Guo, Dong-Bei; Zheng, Han-Ying; Yao, You-Liang; Li, Wen-Gang; Lin, Yu-Chun; Lin, Zhong-Ning
巨噬细胞
炎症
炎症/感染
巨噬细胞
代谢
LRP3
NLRP3
囊泡
细胞生物学
免疫/内分泌
发表日期：2026
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Room-Temperature Alane Dehydrogenation for Visible-Light-Driven Photocatalytic Hydrogen Supply System

室温下铝烷脱氢用于可见光驱动的光催化供氢系统

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202518927
Li, Ting-Ting; Liang, Li-Cheng; Chen, Rui-Qi; Zhang, Chun-Qi; Zhang, Sheng-Nan; Cheng, Wen-Wen; Chen, Xi-Hao; Wang, Ning; Xiao, Juan-Ding; Yang, Qing-Qing; Liang, Fei; Zhang, Chao-Feng
发表日期：2026
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Gene therapy via CRISPR/Cas9-mediated Cxcr4 disease allele inactivation reverses leukopenia in WHIM mice

利用 CRISPR/Cas9 介导的 Cxcr4 致病等位基因失活进行基因治疗可逆转 WHIM 小鼠的白细胞减少症。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI202073
Gao, Ji-Liang; Li, Zhanzhuo; Calderon-Perez, Rafael; Pavek, Antonia; Kim, Lina; McDermott, David H; Murphy, Philip M
细胞生物学
基因治疗
发表日期：2026
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Direct cyanation of aromatic rings using dinitrogen and methane promoted by nonthermal plasma

非热等离子体促进的氮气和甲烷对芳环的直接氰化反应

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.ady3414
Yu, Lei; Zhang, Shixiong; Liu, Liang; Li, Di; Cai, Yongli; Wu, Chenxin; Hua, Lei; Li, Haiyang; Deng, Dehui; Chen, Ping; Xi, Zhenfeng; Guo, Jianping; Wei, Junnian
发表日期：2026
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