日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cryo-EM of human P-glycoprotein reveals an intermediate occluded conformation during active drug transport

人P-糖蛋白的冷冻电镜观察显示,在主动药物转运过程中存在一种中间的封闭构象。

Culbertson, Alan T; Liao, Maofu

Lysosome-mediated aggregation of galactose-deficient IgA1 with transferrin receptor 1 links to IgA nephropathy.

溶酶体介导的缺乏半乳糖的 IgA1 与转铁蛋白受体 1 的聚集与 IgA 肾病有关

Si Meijun, Fu Jingpeng, Fang Mengting, Lu Yunfei, Huang Junxuan, Li Haojie, Wang Peiyi, Liao Maofu, Zhu Jian, Li Peiyao, Zhong Wenzhao, Guo Zhifei, Yang Wei, Ye Zhiming, Hu Hongli, Yu Xueqing

Conformational cycle and small-molecule inhibition mechanism of a plant ABCB transporter in lipid membranes

植物ABCB转运蛋白在脂质膜中的构象循环和小分子抑制机制

Liu, Yong; Liao, Maofu

Structural basis of respiratory complex adaptation to cold temperatures.

呼吸系统复杂适应低温的结构基础

Shin Young-Cheul, Latorre-Muro Pedro, Djurabekova Amina, Zdorevskyi Oleksii, Bennett Christopher F, Burger Nils, Song Kangkang, Xu Chen, Paulo Joao A, Gygi Steven P, Sharma Vivek, Liao Maofu, Puigserver Pere

The crystal and cryo-EM structures of PLCγ2 reveal dynamic interdomain recognitions in autoinhibition

PLCγ2的晶体结构和冷冻电镜结构揭示了自身抑制中动态的结构域间识别

Shin, Young-Cheul; Plummer-Medeiros, Ashlee Marie; Mungenast, Alison; Choi, Hyeong-Wook; TenDyke, Karen; Zhu, Xiaojie; Shepard, Jennifer; Sanders, Kristen; Zhuang, Ningning; Hu, Liang; Qian, Dongming; Song, Kangkang; Xu, Chen; Wang, John; Poda, Suresh B; Liao, Maofu; Chen, Yu

DeepSS2GO: protein function prediction from secondary structure

DeepSS2GO:基于二级结构的蛋白质功能预测

Song, Fu V; Su, Jiaqi; Huang, Sixing; Zhang, Neng; Li, Kaiyue; Ni, Ming; Liao, Maofu

The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification

磷脂酰肌醇重塑酶MBOAT7的结构揭示了其催化机制,并有助于抑制剂的鉴定。

Wang, Kun; Lee, Chia-Wei; Sui, Xuewu; Kim, Siyoung; Wang, Shuhui; Higgs, Aidan B; Baublis, Aaron J; Voth, Gregory A; Liao, Maofu; Walther, Tobias C; Farese, Robert V Jr

Analysing an allelic series of rare missense variants of CACNA1I in a Swedish schizophrenia cohort

分析瑞典精神分裂症患者队列中 CACNA1I 罕见错义变异的等位基因系列

Baez-Nieto, David; Allen, Andrew; Akers-Campbell, Seth; Yang, Lingling; Budnik, Nikita; Pupo, Amaury; Shin, Young-Cheul; Genovese, Giulio; Liao, Maofu; Pérez-Palma, Eduardo; Heyne, Henrike; Lal, Dennis; Lipscombe, Diane; Pan, Jen Q

Distinct allosteric mechanisms of first-generation MsbA inhibitors

第一代MsbA抑制剂的独特变构机制

Thélot, François A; Zhang, Wenyi; Song, KangKang; Xu, Chen; Huang, Jing; Liao, Maofu

Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme

人三酰甘油合成酶的结构和催化机制

Sui, Xuewu; Wang, Kun; Gluchowski, Nina L; Elliott, Shane D; Liao, Maofu; Walther, Tobias C; Farese, Robert V Jr