日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deletion of the Saccharomyces cerevisiae RACK1 homolog, ASC1, enhances autophagy which mitigates TDP-43 toxicity

酿酒酵母RACK1同源物ASC1的缺失可增强自噬,从而减轻TDP-43的毒性。

Park, Sei-Kyoung; Park, Sangeun; Liebman, Susan W

Interactions between non-prion and prion domains of Rnq1 direct formation of amyloid vs liquid-like aggregates and create transmission barriers

Rnq1的非朊病毒结构域和朊病毒结构域之间的相互作用决定了淀粉样蛋白聚集体与液态聚集体的形成,并造成了传播屏障。

Park, Sangeun; Maldonado, Dania M; Kadnar, Michele L; Andrade, Monica; Fomitchova, Anna P; Liebman, Susan W; Derkatch, Irina L

Deletion of the Saccharomyces cerevisiae RACK1 homolog, ASC1 , enhances autophagy which mitigates TDP-43 toxicity

酿酒酵母RACK1同源物ASC1的缺失可增强自噬,从而减轻TDP-43的毒性。

Park, Sei-Kyoung; Park, Sangeun; Liebman, Susan W

Exploring Fundamentals of Prion Biology Using Natural Yeast Prions and Mammalian PrP

利用天然酵母朊病毒和哺乳动物朊病毒探索朊病毒生物学的基本原理

Derkatch, Irina L; Liebman, Susan W

Comment on Billant et al. p53, A Victim of the Prion Fashion. Cancers 2021, 13, 269

对 Billant 等人第 53 页文章《朊病毒时尚的受害者》的评论。Cancers 2021, 13, 269

Liebman, Susan W; Derkatch, Irina L; Park, Sangeun; Park, Sei-Kyoung

TDP-43 Toxicity in Yeast Is Associated with a Reduction in Autophagy, and Deletions of TIP41 and PBP1 Counteract These Effects

酵母中TDP-43的毒性与自噬减少有关,而TIP41和PBP1的缺失则能抵消这些影响。

Park, Sei-Kyoung; Park, Sangeun; Liebman, Susan W

Tumor suppressor protein p53 expressed in yeast can remain diffuse, form a prion, or form unstable liquid-like droplets

酵母中表达的肿瘤抑制蛋白p53可以保持弥散状态、形成朊病毒或形成不稳定的液滴状结构。

Park, Sei-Kyoung; Park, Sangeun; Pentek, Christine; Liebman, Susan W

Respiration Enhances TDP-43 Toxicity, but TDP-43 Retains Some Toxicity in the Absence of Respiration

呼吸作用会增强TDP-43的毒性,但即使在没有呼吸作用的情况下,TDP-43仍然保留一定的毒性。

Park, Sei-Kyoung; Park, Sangeun; Liebman, Susan W

Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins

保守的HSP40分子伴侣的过表达可降低多种神经退行性疾病蛋白的毒性。

Park, Sei-Kyoung; Arslan, Fatih; Kanneganti, Vydehi; Barmada, Sami J; Purushothaman, Pravinkumar; Verma, Subhash Chandra; Liebman, Susan W

Inhibition of Aβ(42) oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs

PICALM同源物和某些FDA批准的药物对酵母中Aβ(42)寡聚化的抑制作用

Park, Sei-Kyoung; Ratia, Kiira; Ba, Mariam; Valencik, Maria; Liebman, Susan W