日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance

Raver1 将 Ripk1 RNA 剪接与 caspase-8 介导的细胞焦亡、炎症和病原体抵抗联系起来

Zhang, Boyao; Orning, Pontus; Lehman, Jesse W; Dinis, Alexandre; Torres-Ulloa, Leslie; Elling, Roland; Kelliher, Michelle A; Bertin, John; Proulx, Megan K; Goguen, Jon D; Ryan, Liv; Kandasamy, Richard K; Espevik, Terje; Pai, Athma A; Fitzgerald, Katherine A; Lien, Egil

Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation

即使戒酒后,酒精诱导的细胞外ASC斑点仍会加剧酒精性肝炎中的肝脏炎症和损伤。

de Carvalho Ribeiro, Marcelle; Iracheta-Vellve, Arvin; Babuta, Mrigya; Calenda, Charles D; Copeland, Christopher; Zhuang, Yuan; Lowe, Patrick P; Hawryluk, Danielle; Catalano, Donna; Cho, Yeonhee; Barton, Bruce; Dasarathy, Srinivasan; McClain, Craig; McCullough, Arthur J; Mitchell, Mack C; Nagy, Laura E; Radaeva, Svetlana; Lien, Egil; Golenbock, Douglas T; Szabo, Gyongyi

Multiple roles of caspase-8 in cell death, inflammation, and innate immunity

caspase-8在细胞死亡、炎症和先天免疫中发挥多种作用

Orning, Pontus; Lien, Egil

Inhibition of HSP90 and Activation of HSF1 Diminish Macrophage NLRP3 Inflammasome Activity in Alcohol-Associated Liver Injury

抑制HSP90和激活HSF1可降低酒精相关性肝损伤中巨噬细胞NLRP3炎症小体的活性

Choudhury, Asmita; Bullock, Daniel; Lim, Arlene; Argemi, Josepmaria; Orning, Pontus; Lien, Egil; Bataller, Ramon; Mandrekar, Pranoti

Gasdermins and their role in immunity and inflammation

Gasdermins及其在免疫和炎症中的作用

Orning, Pontus; Lien, Egil; Fitzgerald, Katherine A

Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death

病原体阻断TAK1可触发caspase-8依赖性的gasdermin D裂解和细胞死亡

Orning, Pontus; Weng, Dan; Starheim, Kristian; Ratner, Dmitry; Best, Zachary; Lee, Bettina; Brooks, Alexandria; Xia, Shiyu; Wu, Hao; Kelliher, Michelle A; Berger, Scott B; Gough, Peter J; Bertin, John; Proulx, Megan M; Goguen, Jon D; Kayagaki, Nobuhiko; Fitzgerald, Katherine A; Lien, Egil

A Sugar Rush for Innate Immunity

糖分冲击先天免疫力

Orning, Pontus; Flo, Trude H; Lien, Egil

Bacterial secretion systems and regulation of inflammasome activation

细菌分泌系统与炎症小体激活的调控

Ratner, Dmitry; Orning, M Pontus A; Lien, Egil

The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation

鼠疫耶尔森菌效应蛋白YopM抑制Pyrin炎症小体活化

Ratner, Dmitry; Orning, M Pontus A; Proulx, Megan K; Wang, Donghai; Gavrilin, Mikhail A; Wewers, Mark D; Alnemri, Emad S; Johnson, Peter F; Lee, Bettina; Mecsas, Joan; Kayagaki, Nobuhiko; Goguen, Jon D; Lien, Egil

Mammalian Lipopolysaccharide Receptors Incorporated into the Retroviral Envelope Augment Virus Transmission

整合到逆转录病毒包膜中的哺乳动物脂多糖受体增强病毒传播

Wilks, Jessica; Lien, Egil; Jacobson, Amy N; Fischbach, Michael A; Qureshi, Nilofer; Chervonsky, Alexander V; Golovkina, Tatyana V