日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines

EPA和DHA酰基肉碱的心脏毒性低于饱和和单不饱和长链酰基肉碱。

期刊:Biofactors
影响因子:5
doi:10.1002/biof.70014
Edgars Liepinsh ，Baiba Gukalova ，Kristaps Krims-Davis ，Janis Kuka ，Aiga Leduskrasta ，Stanislava Korzh ，Reinis Vilskersts ，Marina Makrecka-Kuka ，Ilze Konrade ，Maija Dambrova
毒理研究
发表日期：2025
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Testing Strategies for Metabolite-Mediated Neurotoxicity

代谢物介导的神经毒性检测策略

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26178338
Suess, Julian; Reinmoeller, Moritz; Magel, Viktoria; Gukalova, Baiba; Liepinsh, Edgars; Gardner, Iain; Dreser, Nadine; Holzer, Anna-Katharina; Leist, Marcel
毒理研究
代谢
发表日期：2025
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LC-MS/MS-based simultaneous quantification of acylcarnitines, eicosapentaenoic acid, and docosahexaenoic acid: exploring potential biomarkers in human plasma.

基于 LC-MS/MS 的酰基肉碱、二十碳五烯酸和二十二碳六烯酸的同时定量：探索人类血浆中的潜在生物标志物

期刊:Analytical and Bioanalytical Chemistry
影响因子:3.8
doi:10.1007/s00216-025-05943-8
Gukalova Baiba, Krims-Davis Kristaps, Sevostjanovs Eduards, Leduskrasta Aiga, Konrade Ilze, Dambrova Maija, Liepinsh Edgars
Human
发表日期：2025
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Model-informed drug development for antimicrobials: translational pharmacokinetic-pharmacodynamic modelling of apramycin to facilitate prediction of efficacious dose in complicated urinary tract infections

基于模型指导的抗菌药物研发：阿普拉霉素转化药代动力学-药效学模型在预测复杂尿路感染有效剂量中的应用

期刊:Journal of Antimicrobial Chemotherapy
影响因子:3.6
doi:10.1093/jac/dkae409
Hernández-Lozano, Irene; Aranzana-Climent, Vincent; Cao, Sha; Matias, Carina; Ulf Hansen, Jon; Liepinsh, Edgars; Hughes, Diarmaid; Hobbie, Sven N; Vingsbo Lundberg, Carina; Friberg, Lena E
炎症/感染
发表日期：2025
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Conceptual foundations of acetylcarnitine supplementation in neuropsychiatric long COVID syndrome: a narrative review

乙酰肉碱补充剂治疗神经精神性新冠长期综合征的概念基础：叙述性综述

期刊:European Archives of Psychiatry and Clinical Neuroscience
影响因子:3.7
doi:10.1007/s00406-023-01734-3
Helbing, Dario Lucas; Dommaschk, Eva-Maria; Danyeli, Lena Vera; Liepinsh, Edgars; Refisch, Alexander; Sen, Zümrüt Duygu; Zvejniece, Liga; Rocktäschel, Tonia; Stabenow, Leonie Karoline; Schiöth, Helgi B; Walter, Martin; Dambrova, Maija; Besteher, Bianca
微生物学
新冠
发表日期：2024
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Data on cardiac and vascular functionality in ex vivo and in vivo models following acute administration of trimethylamine N-oxide

急性给予三甲胺N-氧化物后，离体和体内模型中心脏和血管功能的数据

期刊:Data in Brief
影响因子:1.4
doi:10.1016/j.dib.2023.108890
Videja, Melita; Vilskersts, Reinis; Sevostjanovs, Eduards; Liepinsh, Edgars; Dambrova, Maija
发表日期：2023
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Fasting-Mimicking Diet Reduces Trimethylamine N-Oxide Levels and Improves Serum Biochemical Parameters in Healthy Volunteers

模拟禁食饮食可降低健康志愿者体内三甲胺N-氧化物水平并改善血清生化指标

期刊:Nutrients
影响因子:5
doi:10.3390/nu14051093
Videja, Melita; Sevostjanovs, Eduards; Upmale-Engela, Sabine; Liepinsh, Edgars; Konrade, Ilze; Dambrova, Maija
发表日期：2022
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Pharmacological activation of PPARβ/δ preserves mitochondrial respiratory function in ischemia/reperfusion via stimulation of fatty acid oxidation-linked respiration and PGC-1α/NRF-1 signaling

PPARβ/δ 的药理激活可通过刺激脂肪酸氧化相关呼吸和 PGC-1α/NRF-1 信号传导来维持缺血/再灌注中的线粒体呼吸功能

期刊:Frontiers in Endocrinology
影响因子:
doi:10.3389/fendo.2022.941822
Ioanna Papatheodorou, Marina Makrecka-Kuka, Janis Kuka, Edgars Liepinsh, Maija Dambrova, Antigone Lazou
信号转导
WB
发表日期：2022
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Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis

阿普拉霉素在酸性pH条件下的抗菌活性使其在治疗复杂性尿路感染和急性肾盂肾炎方面具有较宽的治疗窗口。

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2021.103652
Becker, Katja; Cao, Sha; Nilsson, Anna; Erlandsson, Maria; Hotop, Sven-Kevin; Kuka, Janis; Hansen, Jon; Haldimann, Klara; Grinberga, Solveiga; Berruga-Fernández, Talia; Huseby, Douglas L; Shariatgorji, Reza; Lindmark, Evelina; Platzack, Björn; Böttger, Erik C; Crich, David; Friberg, Lena E; Vingsbo Lundberg, Carina; Hughes, Diarmaid; Brönstrup, Mark; Andrén, Per E; Liepinsh, Edgars; Hobbie, Sven N
炎症/感染
肾炎
发表日期：2021
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Model-Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin

基于模型指导的抗菌药物研发：转化药代动力学和药代动力学/药效学模型预测阿普拉霉素的有效人体剂量

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.2104
Sou, Tomás; Hansen, Jon; Liepinsh, Edgars; Backlund, Maria; Ercan, Onur; Grinberga, Solveiga; Cao, Sha; Giachou, Paraskevi; Petersson, Anna; Tomczak, Magdalena; Urbas, Malgorzata; Zabicka, Dorota; Vingsbo Lundberg, Carina; Hughes, Diarmaid; Hobbie, Sven N; Friberg, Lena E
Human
发表日期：2021
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