日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synergistic reduction in interfacial flexibility of TREM2(R47H) and ApoE4 may underlie AD pathology

TREM2(R47H)和ApoE4界面柔性的协同降低可能是AD病理的基础。

Lietzke, Emma E; Saeb, David; Aldrich, Emma C; Bruce, Kimberley D; Sprenger, Kayla G

The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids

sTREM2的柔性茎结构域调节其与脑内磷脂的相互作用

Saeb, David; Lietzke, Emma E; Fuchs, Daisy I; Aldrich, Emma C; Bruce, Kimberley D; Sprenger, Kayla G

Lipid and lipoprotein metabolism in microglia: Alzheimer's disease mechanisms and interventions

小胶质细胞中的脂质和脂蛋白代谢:阿尔茨海默病机制和干预措施

Sprenger, Kayla G; Lietzke, Emma E; Melchior, John T; Bruce, Kimberley D

Lipoprotein lipase requires a flexible lid and stable C-terminal, both maintained by ApoC-II peptide binding

脂蛋白脂肪酶需要一个灵活的盖子和一个稳定的C端,这两者都由ApoC-II肽的结合来维持。

Lietzke, Emma E; Rouse, Mary S; Oldham, Dean; Dong, Ziyue; Eckel, Robert H; Sprenger, Kayla G; Bruce, Kimberley D

Using Synthetic ApoC-II Peptides and nAngptl4 Fragments to Measure Lipoprotein Lipase Activity in Radiometric and Fluorescent Assays.

利用合成的 ApoC-II 肽和 nAngptl4 片段在放射性测定和荧光测定中测量脂蛋白脂肪酶活性

Oldham Dean, Wang Hong, Mullen Juliet, Lietzke Emma, Sprenger Kayla, Reigan Philip, Eckel Robert H, Bruce Kimberley D