A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer.
NOTCH1 基因拷贝数增加是预后不良的指标，也是结直肠癌中 Notch1 靶向抗体的预测性生物标志物
期刊:International Journal of Cancer
影响因子:4.7
doi:10.1002/ijc.29676
Arcaroli John J, Tai W M, McWilliams Ryan, Bagby Stacey, Blatchford Patrick J, Varella-Garcia Marileila, Purkey Alicia, Quackenbush Kevin S, Song Eun-Kee, Pitts Todd M, Gao Dexiang, Lieu Chris, McManus Martine, Tan Aik Choon, Zheng Xianxian, Zhang Qin, Ozeck Mark, Olson Peter, Jiang Zhi-Qin, Kopetz Scott, Jimeno Antonio, Keysar Stephen, Eckhardt Gail, Messersmith Wells A
