日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Predicting homologous recombination deficiency and treatment responses using a computed tomography-based foundation model: a preclinical study

利用基于计算机断层扫描的基础模型预测同源重组缺陷和治疗反应：一项临床前研究

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-026-01322-3
Kuang, Sheng; Schuitmaker, Lesley; Wu, Min; Salahuddin, Zohaib; van der Wiel, Alexander; van de Laak, Jella; Lieuwes, Natasja; Biemans, Rianne; Jung, Jennifer; Yaromina, Ala; Dubois, Ludwig J; Woodruff, Henry C; Lambin, Philippe
发表日期：2026
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Deficiencies in the Fanconi anemia or homologous recombination pathway enhance the antitumor effects of the hypoxia-activated prodrug CP-506

范可尼贫血或同源重组途径的缺陷会增强缺氧激活前药CP-506的抗肿瘤作用。

期刊:Molecular Therapy Oncology
影响因子:5.3
doi:10.1016/j.omton.2026.201161
Schuitmaker, Lesley; van der Wiel, Alexander M A; Lieuwes, Natasja G; Biemans, Rianne; Mutsters, Nikki A M; Jung, Jennifer; Bastos, Victoria Claudino; Sagarra, Èlia Prades; Kuang, Sheng; Setton, Jeremy; Langie, Sabine A S; Kampen, Kim R; Theys, Jan; Yaromina, Ala; Dubois, Ludwig J; Lambin, Philippe
肿瘤
贫血
肿瘤免疫
代谢
发表日期：2026
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The Effect of Dietary Fiber Compositions on the Therapeutic Outcome of Combined Radio- and Immunotherapy in a Preclinical Cancer Model

膳食纤维组成对临床前癌症模型中联合放疗和免疫疗法疗效的影响

期刊:Molecular Nutrition & Food Research
影响因子:4.2
doi:10.1002/mnfr.70370
Westheim, Annemarie J F; Dubois, Ludwig J; Prades-Sagarra, Elia; Chan, Jiyang; van der Wiel, Alexander M A; Lieuwes, Natasja G; Biemans, Rianne; Cong, Ying; Houben, Tom; Meesters, Dennis M; Yaromina, Ala; van Dijk, Miriam; van Bergenhenegouwen, Jeroen; van Helvoort, Ardy; Langen, Ramon C J; Penders, John; Shiri-Sverdlov, Ronit; Theys, Jan
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2026
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Development of a novel anti-CEACAM5 VHH for SPECT imaging and potential cancer therapy applications.

开发一种新型抗CEACAM5 VHH用于SPECT成像和潜在的癌症治疗应用

期刊:European Journal of Nuclear Medicine and Molecular Imaging
影响因子:7.6
doi:10.1007/s00259-025-07321-z
Cong Ying, Biemans Rianne, Lieuwes Natasja G, Suijlen Dennis, Lambin Philippe, Dijkgraaf Ingrid, Bauwens Matthias, Yaromina Ala, Dubois Ludwig J
肿瘤
肿瘤免疫
发表日期：2025
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Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer

靶向丝氨酸/甘氨酸代谢可改善非小细胞肺癌的放射治疗反应

期刊:British Journal of Cancer
影响因子:6.4
doi:10.1038/s41416-023-02553-y
Anaís Sánchez-Castillo ，Elien Heylen ，Judith Hounjet ，Kim G Savelkouls ，Natasja G Lieuwes ，Rianne Biemans ，Ludwig J Dubois ，Kobe Reynders ，Kasper M Rouschop ，Rianne D W Vaes ，Kim De Keersmaecker ，Maarten Lambrecht ，Lizza E L Hendriks ，Dirk K M De Ruysscher ，Marc Vooijs ，Kim R Kampen
代谢
肿瘤免疫
细胞生物学
肺癌
肿瘤
发表日期：2024
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Treating colorectal peritoneal metastases with an injectable cytostatic loaded supramolecular hydrogel in a rodent animal model

使用可注射的载有细胞抑制剂的超分子水凝胶在啮齿动物模型中治疗结肠直肠腹膜转移

期刊:Clinical & Experimental Metastasis
影响因子:4.2
doi:10.1007/s10585-023-10210-0
Anne G W E Wintjens, Hong Liu, Peter-Paul K H Fransen, Kaatje Lenaerts, Geert C van Almen, Marion J Gijbels, M'hamed Hadfoune, Bas T C Boonen, Natasja G Lieuwes, Rianne Biemans, Ludwig J Dubois, Patricia Y W Dankers, Ignace H J T de Hingh, Nicole D Bouvy
细胞生物学
其它细胞
发表日期：2023
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Inter-observer variability of organ contouring for preclinical studies with cone beam Computed Tomography imaging

锥形束计算机断层扫描成像在临床前研究中器官轮廓勾画的观察者间差异

期刊:Physics and Imaging in Radiation Oncology
影响因子:3.3
doi:10.1016/j.phro.2022.01.002
Lappas, Georgios; Staut, Nick; Lieuwes, Natasja G; Biemans, Rianne; Wolfs, Cecile J A; van Hoof, Stefan J; Dubois, Ludwig J; Verhaegen, Frank
发表日期：2022
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'On the Spot' Digital Pathology of Breast Cancer Based on Single-Cell Mass Spectrometry Imaging

基于单细胞质谱成像的乳腺癌“现场”数字病理学

期刊:Analytical Chemistry
影响因子:
doi:10.1021/acs.analchem.1c05238
Cuypers, Eva; Claes, Britt S R; Biemans, Rianne; Lieuwes, Natasja G; Glunde, Kristine; Dubois, Ludwig; Heeren, Ron M A
肿瘤
肿瘤免疫
乳腺癌
细胞生物学
单细胞
发表日期：2022
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Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19-IL2 cures poorly immunogenic tumors when combined with radiotherapy

利用抗PD-L1抗体解除肿瘤免疫的抑制，并利用L19-IL2抗体加速肿瘤免疫反应，联合放射疗法可治愈免疫原性较差的肿瘤。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2020-001764
Olivo Pimentel, Veronica; Marcus, Damiënne; van der Wiel, Alexander Ma; Lieuwes, Natasja G; Biemans, Rianne; Lieverse, Relinde Iy; Neri, Dario; Theys, Jan; Yaromina, Ala; Dubois, Ludwig J; Lambin, Philippe
肿瘤
IL2
肿瘤免疫
PD-L1
免疫/内分泌
发表日期：2021
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Selectively Targeting Tumor Hypoxia With the Hypoxia-Activated Prodrug CP-506

利用缺氧激活前药 CP-506 选择性靶向肿瘤缺氧

期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-21-0406
Alexander M A van der Wiel #, Victoria Jackson-Patel #, Raymon Niemans #, Ala Yaromina, Emily Liu, Damiënne Marcus, Alexandra M Mowday, Natasja G Lieuwes, Rianne Biemans, Xiaojing Lin, Zhe Fu, Sisira Kumara, Arthur Jochems, Amir Ashoorzadeh, Robert F Anderson, Kevin O Hicks, Matthew R Bull, Maria R
肿瘤
发表日期：2021
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