Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target
基于细胞的cccDNA报告基因检测结合功能基因组学,鉴定出YBX1是HBV cccDNA宿主因子和抗病毒候选靶点。
期刊:Gut
影响因子:25.8
doi:10.1136/gutjnl-2020-323665
Verrier, Eloi R; Ligat, Gaëtan; Heydmann, Laura; Doernbrack, Katharina; Miller, Julija; Maglott-Roth, Anne; Jühling, Frank; El Saghire, Houssein; Heuschkel, Margaux J; Fujiwara, Naoto; Hsieh, Sen-Yung; Hoshida, Yujin; Root, David E; Felli, Emanuele; Pessaux, Patrick; Mukherji, Atish; Mailly, Laurent; Schuster, Catherine; Brino, Laurent; Nassal, Michael; Baumert, Thomas F