日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Clinical validation of a tissue-agnostic genome-wide methylome enrichment assay to monitor response to pembrolizumab

组织非特异性全基因组甲基化组富集检测方法的临床验证,用于监测帕博利珠单抗的疗效

Stutheit-Zhao, Eric Y; Zhong, Yongqi; Melton, Collin A; Lightbody, Elizabeth D; Hinterberg, Michael A; Wang, Yarong; Hall, Owen; Sosa, Eduardo V; Provance, Jeremy B; Zhang, Junjun; Licon, Abel; Liu, Zhihui Amy; Abdul Razak, Albiruni R; Spreafico, Anna; Bedard, Philippe L; Hansen, Aaron R; Lheureux, Stephanie; Ohashi, Pamela S; Williams, Alan; Bratman, Scott V; Allen, Brian A; Zhang, Jing; De Carvalho, Daniel D; Hartman, Anne-Renee; Siu, Lillian L; Sanz-Garcia, Enrique

Genomic landscape of multiple myeloma and its precursor conditions

多发性骨髓瘤及其前驱疾病的基因组图谱

Alberge, Jean-Baptiste; Dutta, Ankit K; Poletti, Andrea; Coorens, Tim H H; Lightbody, Elizabeth D; Toenges, Rosa; Loinaz, Xavi; Wallin, Sofia; Dunford, Andrew; Priebe, Oliver; Dagan, Johnathan; Boehner, Cody J; Horowitz, Erica; Su, Nang K; Barr, Hadley; Hevenor, Laura; Towle, Katherine; Beesam, Rashmika; Beckwith, Jenna B; Perry, Jacqueline; Cordas Dos Santos, David M; Bertamini, Luca; Greipp, Patricia T; Kübler, Kirsten; Arndt, Peter F; Terragna, Carolina; Zamagni, Elena; Boyle, Eileen M; Yong, Kwee; Morgan, Gareth; Walker, Brian A; Dimopoulos, Meletios Athanasios; Kastritis, Efstathios; Hess, Julian; Sklavenitis-Pistofidis, Romanos; Stewart, Chip; Getz, Gad; Ghobrial, Irene M

Large-scale dependency and drug screens to characterize the therapeutic vulnerabilities of multiple myeloma with 1q

大规模依赖性研究和药物筛选,旨在明确1q多发性骨髓瘤的治疗弱点

Sklavenitis-Pistofidis, Romanos; Lightbody, Elizabeth D; Reidy, Mairead; Tsuji, Junko; Alberge, Jean-Baptiste; Aranha, Michelle P; Heilpern-Mallory, Daniel; Roweth, Harvey G; Huynh, Daisy; Chong, Stephen J F; Chung, Anna Y; Zhang, Jeremy; Hackett, Liam; Haradhvala, Nicholas J; Wu, Ting; Su, Nang K; Berrios, Brianna; Belkin, Saveliy; Dutta, Ankit K; Knudson, Ryan A; Brandt, Carolyn; Greipp, Patricia T; Davids, Matthew S; Papaioannou, Maria; Getz, Gad; Ghobrial, Irene M; Manier, Salomon

Serum free light chains in a racially diverse population including African Americans and populations from South Africa

在包括非裔美国人和南非人群在内的种族多元化人群中检测血清游离轻链

Bertamini, Luca; Alberge, Jean-Baptiste; Lee, David J; El-Khoury, Habib; Kim, Sungjae; Fleming, Grace; Murphy, Ciara; Colchie, Julia; Davis, Maya I; Perry, Jacqueline; Lightbody, Elizabeth D; Allam, Sabine; Goqwana, Lindokuhle N; Philip, Vinitha; Smyth, Natalie; Sakrikar, Dhananjay; Perkins, Mark; Harding, Stephen; Troske, Derek; Getz, Gad; Karlson, Elizabeth W; Munshi, Nikhil; Anderson, Kenneth C; Trippa, Lorenzo; Marinac, Catherine R; Chen, Wenlong C; Joffe, Maureen; Ghobrial, Irene M

Deeper response predicts better outcomes in high-risk-smoldering-myeloma: results of the I-PRISM phase II clinical trial

更深层次的治疗反应预示着高危冒烟型多发性骨髓瘤患者更好的预后:I-PRISM II期临床试验结果

Nadeem, Omar; Aranha, Michelle P; Redd, Robert; Timonian, Michael; Magidson, Sophie; Lightbody, Elizabeth D; Alberge, Jean-Baptiste; Bertamini, Luca; Dutta, Ankit K; El-Khoury, Habib; Bustoros, Mark; Laubach, Jacob P; Bianchi, Giada; O'Donnell, Elizabeth; Wu, Ting; Tsuji, Junko; Anderson, Kenneth C; Getz, Gad; Trippa, Lorenzo; Richardson, Paul G; Sklavenitis-Pistofidis, Romanos; Ghobrial, Irene M

Single-cell RNA sequencing defines distinct disease subtypes and reveals hypo-responsiveness to interferon in asymptomatic Waldenstrom's Macroglobulinemia.

单细胞 RNA 测序定义了不同的疾病亚型,并揭示了无症状华氏巨球蛋白血症对干扰素的低反应性

Sklavenitis-Pistofidis Romanos, Konishi Yoshinobu, Heilpern-Mallory Daniel, Wu Ting, Tsakmaklis Nicholas, Aranha Michelle P, Hunter Zachary R, Ali Alaa K, Tsuji Junko, Haradhvala Nicholas J, Lightbody Elizabeth D, Towle Katherine, Hevenor Laura, Romee Rizwan, Briercheck Edward L, Smith Eric L, Liacos Christine-Ivy, Kastritis Efstathios, Dimopoulos Meletios A, Treon Steven P, Getz Gad, Ghobrial Irene M

Numbat-multiome: inferring copy number variations by combining RNA and chromatin accessibility information from single-cell data

Numbat-multiome:结合单细胞数据的RNA和染色质可及性信息推断拷贝数变异

Li, Ruitong; Alberge, Jean-Baptiste; Keshavarzian, Tina; Tsuji, Junko; Gustafsson, Johan; Rahmat, Mahshid; Lightbody, Elizabeth D; Deng, Stephanie L; Riviero, Santiago; Miller, Mendy; Naz Cemre Kalayci, F; Wiestner, Adrian; Sun, Clare; Lupien, Mathieu; Ghobrial, Irene; Parry, Erin; Gao, Teng; Getz, Gad

Inhibition of MICA and MICB shedding enhances memory-like NK-cell-mediated cytotoxicity against multiple myeloma

抑制MICA和MICB脱落可增强记忆样NK细胞介导的抗多发性骨髓瘤细胞毒性

Tahri, Sabrin; Piccinelli, Sara; Su, Nang Kham; Lampe, Luisa; Dong, Han; Vergara Cadavid, Juliana; Boiarsky, Rebecca; Papazian, Natalie; Lightbody, Elizabeth D; Cao, Amanda; Alberge, Jean-Baptiste; Ferrari de Andrade, Lucas; Rahmat, Mahshid; Shen, Yujia; Blanco Fernández, Laura; Zabaleta, Aintzane; Günther, Andreas; Getz, Gad; Sonneveld, Pieter; Cupedo, Tom; Wucherpfennig, Kai W; Ghobrial, Irene M; Romee, Rizwan

Attenuated response to SARS-CoV-2 vaccine in patients with asymptomatic precursor stages of multiple myeloma and Waldenstrom macroglobulinemia

在患有无症状多发性骨髓瘤和华氏巨球蛋白血症前期阶段的患者中,对SARS-CoV-2疫苗的反应减弱。

Konishi, Yoshinobu; Sklavenitis-Pistofidis, Romanos; Yue, Hong; Ferrari, Federico; Redd, Robert A; Lightbody, Elizabeth D; Russo, Massimiliano; Perry, Jacqueline; Horowitz, Erica; Justis, Anna V; Shayegh, Nader A; Savell, Alexandra; Prescott, Julia; Varmeh, Shohreh; Nowak, Radosław P; Hamilton, Mark; Auclair, Daniel; Marinac, Catherine R; Trippa, Lorenzo; Fischer, Eric S; Ghobrial, Irene M

Prevalence of monoclonal gammopathies and clinical outcomes in a high-risk US population screened by mass spectrometry: a multicentre cohort study

通过质谱筛查美国高危人群中单克隆丙种球蛋白病患病率和临床结局:一项多中心队列研究

El-Khoury, Habib; Lee, David J; Alberge, Jean-Baptiste; Redd, Robert; Cea-Curry, Christian J; Perry, Jacqueline; Barr, Hadley; Murphy, Ciara; Sakrikar, Dhananjay; Barnidge, David; Bustoros, Mark; Leblebjian, Houry; Cowan, Anna; Davis, Maya I; Amstutz, Julia; Boehner, Cody J; Lightbody, Elizabeth D; Sklavenitis-Pistofidis, Romanos; Perkins, Mark C; Harding, Stephen; Mo, Clifton C; Kapoor, Prashant; Mikhael, Joseph; Borrello, Ivan M; Fonseca, Rafael; Weiss, Scott T; Karlson, Elizabeth; Trippa, Lorenzo; Rebbeck, Timothy R; Getz, Gad; Marinac, Catherine R; Ghobrial, Irene M