Ligozio相关文献与解析，生知库 | 链接生命科学的每一步

Automated detection of spinal bone marrow oedema in axial spondyloarthritis: training and validation using two large phase 3 trial datasets

利用两个大型3期临床试验数据集对中轴型脊柱关节炎患者的脊柱骨髓水肿进行自动检测：训练和验证

Jamaludin, Amir; Windsor, Rhydian; Ather, Sarim; Kadir, Timor; Zisserman, Andrew; Braun, Juergen; Gensler, Lianne S; Østergaard, Mikkel; Poddubnyy, Denis; Coroller, Thibaud; Porter, Brian; Ligozio, Gregory; Readie, Aimee; Machado, Pedro M

关节炎

发表日期：2025

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Correction: Evidence of brain target engagement in Parkinson's disease and multiple sclerosis by the investigational nanomedicine, CNM- Au8, in the REPAIR phase 2 clinical trials

更正：在 REPAIR II 期临床试验中，研究性纳米药物 CNM-Au8 显示出与帕金森病和多发性硬化症脑靶点结合的证据

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-023-02269-4

Ren, Jimin; Dewey, Richard B 3rd; Rynders, Austin; Evan, Jacob; Evan, Jeremy; Ligozio, Shelia; Ho, Karen S; Sguigna, Peter V; Glanzman, Robert; Hotchkin, Michael T; Dewey, Richard B Jr; Greenberg, Benjamin M

Evidence of brain target engagement in Parkinson's disease and multiple sclerosis by the investigational nanomedicine, CNM-Au8, in the REPAIR phase 2 clinical trials

REPAIR II 期临床试验中，研究性纳米药物 CNM-Au8 显示出与帕金森病和多发性硬化症脑靶点结合的证据

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-023-02236-z

Efficacy and safety of CNM-Au8 in amyotrophic lateral sclerosis (RESCUE-ALS study): a phase 2, randomised, double-blind, placebo-controlled trial and open label extension

CNM-Au8治疗肌萎缩侧索硬化症的疗效和安全性（RESCUE-ALS研究）：一项2期随机、双盲、安慰剂对照试验及开放标签扩展研究

期刊:EClinicalMedicine

影响因子:10

doi:10.1016/j.eclinm.2023.102036

Vucic, Steve; Menon, Parvathi; Huynh, William; Mahoney, Colin; Ho, Karen S; Hartford, Alan; Rynders, Austin; Evan, Jacob; Evan, Jeremy; Ligozio, Shelia; Glanzman, Robert; Hotchkin, Michael T; Kiernan, Matthew C

ALS

发表日期：2023

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A deep learning approach to private data sharing of medical images using conditional generative adversarial networks (GANs)

基于条件生成对抗网络（GAN）的深度学习方法在医学图像私有数据共享中的应用

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0280316

Sun, Hanxi; Plawinski, Jason; Subramaniam, Sajanth; Jamaludin, Amir; Kadir, Timor; Readie, Aimee; Ligozio, Gregory; Ohlssen, David; Baillie, Mark; Coroller, Thibaud

GAN

发表日期：2023

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Quantification of pre-existing radiographic damage and its relationship with joint activity and long-term clinical outcomes with secukinumab therapy in patients with psoriatic arthritis

量化既往放射学损伤及其与银屑病关节炎患者接受司库奇尤单抗治疗后的关节活动度和长期临床疗效的关系

期刊:Arthritis Research & Therapy

影响因子:4.6

doi:10.1186/s13075-022-02944-1

Mease, Philip; van der Heijde, Désirée; Kirkham, Bruce; Schett, Georg; Orbai, Ana-Maria; Ritchlin, Christopher; Merola, Joseph F; Pricop, Luminita; James, David A; Zhu, Xuan; Ligozio, Gregory

Clinically relevant patient clusters identified by machine learning from the clinical development programme of secukinumab in psoriatic arthritis

通过机器学习从司库奇尤单抗治疗银屑病关节炎的临床开发项目中识别出具有临床意义的患者群体

期刊:RMD Open

影响因子:4.7

doi:10.1136/rmdopen-2021-001845

Pournara, Effie; Kormaksson, Matthias; Nash, Peter; Ritchlin, Christopher T; Kirkham, Bruce W; Ligozio, Gregory; Pricop, Luminita; Ogdie, Alexis; Coates, Laura C; Schett, Georg; McInnes, Iain B

Advancing data science in drug development through an innovative computational framework for data sharing and statistical analysis

通过创新的数据共享和统计分析计算框架，推进药物研发中的数据科学发展

期刊:BMC Medical Research Methodology

影响因子:3.4

doi:10.1186/s12874-021-01409-4

Mallon, Ann-Marie; Häring, Dieter A; Dahlke, Frank; Aarden, Piet; Afyouni, Soroosh; Delbarre, Daniel; El Emam, Khaled; Ganjgahi, Habib; Gardiner, Stephen; Kwok, Chun Hei; West, Dominique M; Straiton, Ewan; Haemmerle, Sibylle; Huffman, Adam; Hofmann, Tom; Kelly, Luke J; Krusche, Peter; Laramee, Marie-Claude; Lheritier, Karine; Ligozio, Greg; Readie, Aimee; Santos, Luis; Nichols, Thomas E; Branson, Janice; Holmes, Chris

发表日期：2021

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Secukinumab Efficacy in Psoriatic Arthritis: Machine Learning and Meta-analysis of Four Phase 3 Trials

司库奇尤单抗治疗银屑病关节炎的疗效：基于机器学习和四项3期临床试验的荟萃分析

期刊:Jcr-Journal of Clinical Rheumatology

影响因子:1.8

doi:10.1097/RHU.0000000000001302

Gottlieb, Alice B; Mease, Philip J; Kirkham, Bruce; Nash, Peter; Balsa, Alejandro C; Combe, Bernard; Rech, Jürgen; Zhu, Xuan; James, David; Martin, Ruvie; Ligozio, Gregory; Abrams, Ken; Pricop, Luminita

Learning from multiple readings for axial spondyloarthritis classification of the sacroiliac joints

从多篇文献中学习骶髂关节轴性脊柱关节炎的分类

Automated detection of spinal bone marrow oedema in axial spondyloarthritis: training and validation using two large phase 3 trial datasets

利用两个大型3期临床试验数据集对中轴型脊柱关节炎患者的脊柱骨髓水肿进行自动检测：训练和验证

Correction: Evidence of brain target engagement in Parkinson's disease and multiple sclerosis by the investigational nanomedicine, CNM- Au8, in the REPAIR phase 2 clinical trials

更正：在 REPAIR II 期临床试验中，研究性纳米药物 CNM-Au8 显示出与帕金森病和多发性硬化症脑靶点结合的证据

Evidence of brain target engagement in Parkinson's disease and multiple sclerosis by the investigational nanomedicine, CNM-Au8, in the REPAIR phase 2 clinical trials

REPAIR II 期临床试验中，研究性纳米药物 CNM-Au8 显示出与帕金森病和多发性硬化症脑靶点结合的证据

Efficacy and safety of CNM-Au8 in amyotrophic lateral sclerosis (RESCUE-ALS study): a phase 2, randomised, double-blind, placebo-controlled trial and open label extension

CNM-Au8治疗肌萎缩侧索硬化症的疗效和安全性（RESCUE-ALS研究）：一项2期随机、双盲、安慰剂对照试验及开放标签扩展研究

A deep learning approach to private data sharing of medical images using conditional generative adversarial networks (GANs)

基于条件生成对抗网络（GAN）的深度学习方法在医学图像私有数据共享中的应用

Quantification of pre-existing radiographic damage and its relationship with joint activity and long-term clinical outcomes with secukinumab therapy in patients with psoriatic arthritis

量化既往放射学损伤及其与银屑病关节炎患者接受司库奇尤单抗治疗后的关节活动度和长期临床疗效的关系

Clinically relevant patient clusters identified by machine learning from the clinical development programme of secukinumab in psoriatic arthritis

通过机器学习从司库奇尤单抗治疗银屑病关节炎的临床开发项目中识别出具有临床意义的患者群体

Advancing data science in drug development through an innovative computational framework for data sharing and statistical analysis

通过创新的数据共享和统计分析计算框架，推进药物研发中的数据科学发展

Secukinumab Efficacy in Psoriatic Arthritis: Machine Learning and Meta-analysis of Four Phase 3 Trials

司库奇尤单抗治疗银屑病关节炎的疗效：基于机器学习和四项3期临床试验的荟萃分析