Lih-Ching相关文献与解析，生知库 | 链接生命科学的每一步

Repurposing Suan-Zao-Ren-Tang as anticancer agents in apoptotic sensitization against non-small cell lung cancer cell lines through amplification of spindle assembly checkpoint activation

通过增强纺锤体组装检查点激活，将酸枣仁汤重新定位为抗癌药物，以增强对非小细胞肺癌细胞系的凋亡敏感性。

期刊:Journal of Traditional and Complementary Medicine

影响因子:3

doi:10.1016/j.jtcme.2024.08.008

Hsiao, Yu-Chi; Sheng, Yi-Hua; Chen, Tse-Yu; Leu, Wohn-Jenn; Hsu, Jui-Ling; Hsu, Lih-Ching; Lin, Lie-Chwen; Guh, Jih-Hwa

Repurposing dihydroartemisinin as a novel anticancer agent against colorectal cancer stem cells

将双氢青蒿素重新用于对抗结直肠癌干细胞，作为一种新型抗癌药物。

期刊:Journal of Food and Drug Analysis

影响因子:2.6

doi:10.38212/2224-6614.3552.

Meng-Han Wu ,Chieh-Ju Sung ,Fan-Lu Kung ,Jih-Hwa Guh ,Yeu Su ,Lih-Ching Hsu

Doxazosin inhibits vasculogenic mimicry in human non‑small cell lung cancer through inhibition of the VEGF‑A/VE‑cadherin/mTOR/MMP pathway

多沙唑嗪通过抑制 VEGF-A/VE-cadherin/mTOR/MMP 通路抑制人类非小细胞肺癌中的血管生成拟态

期刊:Oncology Letters

影响因子:2.5

doi:10.3892/ol.2024.14303

Jui-Ling Hsu, Wohn-Jenn Leu, Lih-Ching Hsu, Chia-Hsun Hsieh, Jih-Hwa Guh

Anticancer Activity and Molecular Mechanisms of an Ursodeoxycholic Acid Methyl Ester-Dihydroartemisinin Hybrid via a Triazole Linkage in Hepatocellular Carcinoma Cells

通过三唑键连接的熊去氧胆酸甲酯-二氢青蒿素杂化物在肝细胞癌细胞中的抗癌活性和分子机制

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules28052358

Ya-Fen Hsu, Fan-Lu Kung, Tzu-En Huang, Yi-Ning Deng, Jih-Hwa Guh, Paolo Marchetti, Elena Marchesi, Daniela Perrone, Maria Luisa Navacchia, Lih-Ching Hsu

Mechanistic study of dual-function inhibitors targeting topoisomerase II and Rad51-mediated DNA repair pathway against castration-resistant prostate cancer

针对拓扑异构酶II和Rad51介导的DNA修复通路的双功能抑制剂对抗去势抵抗性前列腺癌的机制研究

期刊:Prostate

影响因子:2.6

doi:10.1002/pros.24613

Yi-Chang Chiang, Wohn-Jenn Leu, Yi-Chin Chen, Pei-Chen Ye, Yu-Tung Hsu, Yu-Chi Hsiao, Jui-Ling Hsu, She-Hung Chan, Lih-Ching Hsu, Hsu-Shan Huang, Jih-Hwa Guh

Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells

胆汁酸-双氢青蒿素混合物熊去氧胆酸-双氢青蒿素在肝细胞癌细胞中的抗癌活性评估

期刊:Frontiers in Pharmacology

影响因子:4.4

doi:10.3389/fphar.2020.599067

Tzu-En Huang, Yi-Ning Deng, Jui-Ling Hsu, Wohn-Jenn Leu, Elena Marchesi, Massimo L Capobianco, Paolo Marchetti, Maria Luisa Navacchia, Jih-Hwa Guh, Daniela Perrone, Lih-Ching Hsu

The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis

(+)-Brevipolide H 对人类去势抵抗性前列腺癌具有抗癌活性：氧化应激和 Akt/mTOR/p70S6K 依赖性通路在 G1 检查点阻滞和细胞凋亡中的作用

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules25122929

Yi-Hua Sheng, Wohn-Jenn Leu, Ching-Nung Chen, Jui-Ling Hsu, Ying-Tung Liu, Lih-Ching Hsu, Duen-Ren Hou, Jih-Hwa Guh

Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies

查尔酮通过抑制启动和激活步骤在巨噬细胞中显示抗 NLRP3 炎症小体活性 - 结构-活性-关系和机制研究

期刊:Molecules

影响因子:4.2

doi:10.3390/molecules25245960

Wohn-Jenn Leu, Jung-Chun Chu, Jui-Ling Hsu, Chi-Min Du, Yi-Huei Jiang, Lih-Ching Hsu, Wei-Jan Huang, Jih-Hwa Guh

Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death Against Human Non-Small Cell Lung Cancers

发现纺锤体组装检查点上的新型药物，以增强长春瑞滨诱导的针对人类非小细胞肺癌的有丝分裂细胞死亡的敏感性

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms21165608

Ya-Ching Chang, Yu-Ling Tseng, Wohn-Jenn Leu, Chi-Min Du, Yi-Huei Jiang, Lih-Ching Hsu, Jui-Ling Hsu, Duen-Ren Hou, Jih-Hwa Guh

A Novel HDAC6 Inhibitor Enhances the Efficacy of Paclitaxel Against Ovarian Cancer Cells

一种新型HDAC6抑制剂增强紫杉醇对卵巢癌细胞的疗效

Repurposing Suan-Zao-Ren-Tang as anticancer agents in apoptotic sensitization against non-small cell lung cancer cell lines through amplification of spindle assembly checkpoint activation

通过增强纺锤体组装检查点激活，将酸枣仁汤重新定位为抗癌药物，以增强对非小细胞肺癌细胞系的凋亡敏感性。

Repurposing dihydroartemisinin as a novel anticancer agent against colorectal cancer stem cells

将双氢青蒿素重新用于对抗结直肠癌干细胞，作为一种新型抗癌药物。

Doxazosin inhibits vasculogenic mimicry in human non‑small cell lung cancer through inhibition of the VEGF‑A/VE‑cadherin/mTOR/MMP pathway

多沙唑嗪通过抑制 VEGF-A/VE-cadherin/mTOR/MMP 通路抑制人类非小细胞肺癌中的血管生成拟态

Anticancer Activity and Molecular Mechanisms of an Ursodeoxycholic Acid Methyl Ester-Dihydroartemisinin Hybrid via a Triazole Linkage in Hepatocellular Carcinoma Cells

通过三唑键连接的熊去氧胆酸甲酯-二氢青蒿素杂化物在肝细胞癌细胞中的抗癌活性和分子机制

Mechanistic study of dual-function inhibitors targeting topoisomerase II and Rad51-mediated DNA repair pathway against castration-resistant prostate cancer

针对拓扑异构酶II和Rad51介导的DNA修复通路的双功能抑制剂对抗去势抵抗性前列腺癌的机制研究

Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells

胆汁酸-双氢青蒿素混合物熊去氧胆酸-双氢青蒿素在肝细胞癌细胞中的抗癌活性评估

The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis

(+)-Brevipolide H 对人类去势抵抗性前列腺癌具有抗癌活性：氧化应激和 Akt/mTOR/p70S6K 依赖性通路在 G1 检查点阻滞和细胞凋亡中的作用

Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies

查尔酮通过抑制启动和激活步骤在巨噬细胞中显示抗 NLRP3 炎症小体活性 - 结构-活性-关系和机制研究

Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death Against Human Non-Small Cell Lung Cancers

发现纺锤体组装检查点上的新型药物，以增强长春瑞滨诱导的针对人类非小细胞肺癌的有丝分裂细胞死亡的敏感性