日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Two-step voltage-sensor activation of the human K(V)7.4 channel and effect of a deafness-associated mutation

人类K(V)7.4通道的两步电压传感器激活及其与耳聋相关的突变的影响

Nappi, Mario; Frampton, Damon J A; Kusay, Ali S; Wang, Kaiqian; Yasarbas, S Suheda; Pozzi, Serena; Miceli, Francesco; Liin, Sara I; Taglialatela, Maurizio; Pantazis, Antonios

In vitro γ-aminobutyric acid A (GABA(A)) receptor activity and binding interactions at the α(+)/γ(2)(-) interface of 53 prescription and designer benzodiazepines

53种处方和新型苯二氮卓类药物在α(+)/γ(2)(-)界面处的体外γ-氨基丁酸A(GABA(A))受体活性和结合相互作用

Norman, Caitlyn; Liin, Sara I; Jauregi-Miguel, Amaia; Ottosson, Nina E; Gréen, Henrik

Closed and open structures of the eukaryotic magnesium channel Mrs2 reveal the auto-ligand-gating regulation mechanism.

真核生物镁通道 Mrs2 的闭合和开放结构揭示了其自身配体门控调节机制

Li Ping, Liu Shiyan, Wallerstein Johan, Villones Rhiza Lyne E, Huang Peng, Lindkvist-Petersson Karin, Meloni Gabriele, Lu Kefeng, Steen Jensen Kristine, Liin Sara I, Gourdon Pontus

System-wide targeted analysis of oxylipins and lipoproteins in chronic peripheral neuropathic pain-an explorative study

慢性周围神经性疼痛中氧脂和脂蛋白的系统性靶向分析——一项探索性研究

Jönsson, Mika; Bäckryd, Emmanuel; Ljunggren, Stefan; Ottosson, Nina; Jauregi-Miguel, Amaia; Liin, Sara I; Checa, Antonio; Wheelock, Craig E; Ghafouri, Bijar

Beneficial action potential duration-shortening effects, but deleterious negative inotropism of IKs-activator docosahexaenoyl glycine in long QT syndrome type 2

二十二碳六烯酸甘氨酸(DHA)是一种IKs激活剂,在长QT综合征2型中具有缩短动作电位时程的有益作用,但同时也具有有害的负性肌力作用。

Louradour, Julien; Hornyik, Tibor; De la Cruz, Alicia; Hiniesto-Iñigo, Irene; Alerni, Nicolò; Barbieri, Miriam; Lopez, Ruben; Perez-Feliz, Stefanie; Matas, Lluís; Nimani, Saranda; Giammarino, Lucilla; Koren, Gideon; Zehender, Manfred; Brunner, Michael; Liin, Sara I; Larsson, H Peter; Odening, Katja E

The endocannabinoid ARA-S facilitates the activation of cardiac Kv7.1/KCNE1 channels from different species

内源性大麻素ARA-S促进不同物种心脏Kv7.1/KCNE1通道的激活。

Hiniesto-Iñigo, Irene; Linhart, Veronika A; Kusay, Ali S; Liin, Sara I

Long-QT mutations in KCNE1 modulate the 17β-estradiol response of Kv7.1/KCNE1

KCNE1 中的长 QT 突变调节 Kv7.1/KCNE1 对 17β-雌二醇的反应

Erlandsdotter, Lisa-Marie; Giammarino, Lucilla; Halili, Azemine; Nikesjö, Johan; Gréen, Henrik; Odening, Katja E; Liin, Sara I

Endocannabinoids enhance hKV7.1/KCNE1 channel function and shorten the cardiac action potential and QT interval

内源性大麻素增强 hKV7.1/KCNE1 通道功能并缩短心脏动作电位和 QT 间期

Irene Hiniesto-Iñigo, Laura M Castro-Gonzalez, Valentina Corradi, Mark A Skarsfeldt, Samira Yazdi, Siri Lundholm, Johan Nikesjö, Sergei Yu Noskov, Bo Hjorth Bentzen, D Peter Tieleman, Sara I Liin

Mechanistic insights into robust cardiac IKs potassium channel activation by aromatic polyunsaturated fatty acid analogues

芳香族多不饱和脂肪酸类似物对心脏 IKs 钾通道激活的机制洞察

Briana M Bohannon #, Jessica J Jowais #, Leif Nyberg, Vanessa Olivier-Meo, Valentina Corradi, D Peter Tieleman, Sara I Liin, H Peter Larsson

Mechanistic understanding of KCNQ1 activating polyunsaturated fatty acid analogs

对KCNQ1激活多不饱和脂肪酸类似物的机制理解

Jowais, Jessica J; Yazdi, Samira; Golluscio, Alessia; Olivier-Meo, Vanessa; Liin, Sara I; Larsson, H Peter