日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ceramide-Induced Metabolic Stress Depletes Fumarate and Drives Mitophagy to Mediate Tumor Suppression.

神经酰胺诱导的代谢应激会消耗富马酸并驱动线粒体自噬,从而介导肿瘤抑制

Oleinik Natalia V, Atilgan Firdevs Cansu, Kassir Mohamed Faisal, Lee Han Gyul, Janneh Alhaji H, Wofford Wyatt, Walton Chase, Szulc Zdzislaw M, Hill Elizabeth G, Alekseyenko Alexander V, Cimen Huseyin, Hartman Jessica H, Voelkel-Johnson Christina, Lilly Michael B, Lemasters John J, Frizzell Norma, Yu Xue-Zhong, Mehrotra Shikhar, Ogretmen Besim

Mediator kinase inhibition reverses castration resistance of advanced prostate cancer

介质激酶抑制剂可逆转晚期前列腺癌的去势抵抗性

Li, Jing; Hilimire, Thomas A; Liu, Yueying; Wang, Lili; Liang, Jiaxin; Gyorffy, Balazs; Sikirzhytski, Vitali; Ji, Hao; Zhang, Li; Cheng, Chen; Ding, Xiaokai; Kerr, Kendall R; Dowling, Charles E; Chumanevich, Alexander A; Mack, Zachary T; Schools, Gary P; Lim, Chang-Uk; Ellis, Leigh; Zi, Xiaolin; Porter, Donald C; Broude, Eugenia V; McInnes, Campbell; Wilding, George; Lilly, Michael B; Roninson, Igor B; Chen, Mengqian

A phase I study of docetaxel plus synthetic lycopene in metastatic prostate cancer patients

一项针对转移性前列腺癌患者的多西他赛联合合成番茄红素的I期研究

Lilly, Michael B; Wu, Chunli; Ke, Yu; Chen, Wen-Pin; Soloff, Adam C; Armeson, Kent; Yokoyama, Noriko N; Li, Xiaotian; Song, Liankun; Yuan, Ying; McLaren, Christine E; Zi, Xiaolin

Genomic amplifications identified by circulating tumor DNA analysis guide prognosis in metastatic castration-resistant prostate cancer

循环肿瘤DNA分析鉴定的基因组扩增可指导转移性去势抵抗性前列腺癌的预后判断

Dincman, Toros A; Karam, Joseph A Q; Giordano, Antonio; Li, Hong; Drusbosky, Leylah M; Gourdin, Theodore S; Howe, Philip H; Lilly, Michael B

Comprehensive Genomic Profiling of Cell-Free DNA in Men With Advanced Prostate Cancer: Differences in Genomic Landscape Based on Race

对晚期前列腺癌患者游离DNA进行全面基因组分析:基于种族的基因组图谱差异

Zimmerman, Raquel; Bilen, Mehmet A; Heath, Elisabeth I; Nandagopal, Lakshminarayanan; Swami, Umang; Kessel, Adam; Jaeger, Ellen; Wesolowski, Sergiusz; Hernanadez, Edgar J; Chipman, Jonathan; Mack, Alleda; Ravindranathan, Deepak; Maughan, Benjamin L; Nussenzveig, Roberto; Yandell, Mark; Kohli, Manish; Lilly, Michael B; Sartor, A Oliver; Agarwal, Neeraj; Barata, Pedro C

Racial Distribution of Neighborhood-Level Social Deprivation in a Retrospective Cohort of Prostate Cancer Survivors

前列腺癌幸存者回顾性队列研究中社区层面社会剥夺的种族分布

Babatunde, Oluwole Adeyemi; Pearce, John L; Jefferson, Melanie S; Frey, Lewis J; Angel, Peggi M; Drake, Richard R; Allen, Caitlin G; Lilly, Michael B; Savage, Stephen J; Hughes Halbert, Chanita

Comprehensive Analysis of AR Alterations in Circulating Tumor DNA from Patients with Advanced Prostate Cancer

对晚期前列腺癌患者循环肿瘤DNA中雄激素受体(AR)改变的综合分析

Ledet, Elisa M; Lilly, Michael B; Sonpavde, Guru; Lin, Edwin; Nussenzveig, Roberto H; Barata, Pedro C; Yandell, Mark; Nagy, Rebecca J; Kiedrowski, Lesli; Agarwal, Neeraj; Sartor, Oliver

Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells

PI3K的缺失可阻断小鼠体内BCR-ABL白血病的发生,而PI3K/mTOR双重抑制剂可阻止人BCR-ABL阳性白血病细胞的扩增。

Kharas, Michael G; Janes, Matthew R; Scarfone, Vanessa M; Lilly, Michael B; Knight, Zachary A; Shokat, Kevan M; Fruman, David A

SWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer

SWOG S0925:一项随机II期研究,比较雄激素剥夺联合西妥昔单抗与单纯雄激素剥夺治疗新发转移性激素敏感性前列腺癌患者的疗效

Yu, Evan Y; Li, Hongli; Higano, Celestia S; Agarwal, Neeraj; Pal, Sumanta K; Alva, Ajjai; Heath, Elisabeth I; Lam, Elaine T; Gupta, Shilpa; Lilly, Michael B; Inoue, Yoshio; Chi, Kim N; Vogelzang, Nicholas J; Quinn, David I; Cheng, Heather H; Plymate, Stephen R; Hussain, Maha; Tangen, Catherine M; Thompson, Ian M Jr

Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model

黄酮卡文A诱导NEDDylation和Skp2降解,从而抑制TRAMP转基因小鼠模型中的肿瘤发生和癌症进展。

Li, Xuesen; Yokoyama, Noriko N; Zhang, Saiyang; Ding, Lina; Liu, Hong-min; Lilly, Michael B; Mercola, Dan; Zi, Xiaolin