日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-Cell RNAseq Identifies Heterogeneity in Myoblasts From Older Adults With Differences Related to Muscle Mass and Function

单细胞RNA测序揭示老年人成肌细胞的异质性,这种异质性与肌肉质量和功能相关。

Burton, Mark A; Garratt, Emma S; Sharkh, Hanan Y; Hewitt, Matthew O; Antoun, Elie; Westbury, Leo D; Dennison, Elaine M; Harvey, Nicholas C; Cooper, Cyrus; Patel, Harnish P; Godfrey, Keith M; Lillycrop, Karen A

Short-term diet intervention comprising of olive oil, vitamin D, and omega-3 fatty acids alters the small non-coding RNA (sncRNA) landscape of human sperm

短期饮食干预,包括补充橄榄油、维生素D和ω-3脂肪酸,可以改变人类精子中小非编码RNA(sncRNA)的组成。

Vaz, Candida; Burton, Mark; Kermack, Alexandra J; Tan, Pei Fang; Huan, Jason; Yoo, Tessa P X; Donnelly, Kerry; Wellstead, Susan J; Wang, Dennis; Fisk, Helena L; Houghton, Franchesca D; Lewis, Sheena; Chong, Yap Seng; Gluckman, Peter D; Cheong, Ying; Macklon, Nicholas S; Calder, Philip C; Dutta, Anindya; Godfrey, Keith M; Kumar, Pankaj; Lillycrop, Karen A; Karnani, Neerja

Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

葫芦巴碱是 NAD+ 的前体,可改善衰老过程中的肌肉功能,但在人类肌肉减少症中含量降低。

Mathieu Membrez,Eugenia Migliavacca,Stefan Christen,Keisuke Yaku,Jennifer Trieu,Alaina K Lee,Francesco Morandini,Maria Pilar Giner,Jade Stiner,Mikhail V Makarov,Emma S Garratt ,Maria F Vasiloglou,Lucie Chanvillard,Emilie Dalbram,Amy M Ehrlich,José Luis Sanchez-Garcia,Carles Canto,Leonidas G Karagounis ,Jonas T Treebak,Marie E Migaud,Ramin Heshmat,Farideh Razi,Neerja Karnani ,Afshin Ostovar,Farshad Farzadfar,Stacey K H Tay , Matthew J Sanders,Karen A Lillycrop,Keith M Godfrey,Takashi Nakagawa,Sofia Moco  ,René Koopman,Gordon S Lynch,Vincenzo Sorrentino,Jerome N Feige

The serum small non-coding RNA (SncRNA) landscape as a molecular biomarker of age associated muscle dysregulation and insulin resistance in older adults

血清小分子非编码 RNA (SncRNA) 概况作为老年人年龄相关肌肉失调和胰岛素抵抗的分子生物标志物

Mark A Burton, Elie Antoun, Emma S Garratt, Leo Westbury, Elaine M Dennison, Nicholas C Harvey, Cyrus Cooper, Harnish P Patel, Keith M Godfrey, Karen A Lillycrop

Adiposity is associated with widespread transcriptional changes and downregulation of longevity pathways in aged skeletal muscle

肥胖与衰老骨骼肌中广泛的转录变化和长寿通路的下调有关

Mark A Burton, Elie Antoun, Emma S Garratt, Leo Westbury, Alica Baczynska, Elaine M Dennison, Nicholas C Harvey, Cyrus Cooper, Harnish P Patel, Keith M Godfrey, Karen A Lillycrop; EpiGen Global Research Consortium

Differential DNA methylation of steatosis and non-alcoholic fatty liver disease in adolescence

青少年脂肪变性和非酒精性脂肪肝疾病的差异性DNA甲基化

Melton, Phillip E; Burton, M A; Lillycrop, K A; Godfrey, K M; Rauschert, S; Anderson, D; Burdge, G C; Mori, T A; Beilin, L J; Ayonrinde, O T; Craig, J M; Olynyk, J K; Holbrook, J D; Pennell, C E; Oddy, W H; Moses, E K; Adams, L A; Huang, R C

Oxylipin secretion by human CD3+ T lymphocytes in vitro is modified by the exogenous essential fatty acid ratio and life stage

体外人类 CD3+ T 淋巴细胞的氧化脂质分泌受外源性必需脂肪酸比例和生命阶段的影响

Johanna von Gerichten, Annette L West, Nicola A Irvine, Elizabeth A Miles, Philip C Calder, Karen A Lillycrop, Graham C Burdge, Barbara A Fielding

DNA methylation of insulin signaling pathways is associated with HOMA2-IR in primary myoblasts from older adults

胰岛素信号通路的 DNA 甲基化与老年人原代成肌细胞中的 HOMA2-IR 相关

Mark A Burton #, Emma S Garratt #, Matthew O Hewitt, Hanan Y Sharkh, Elie Antoun, Leo D Westbury, Elaine M Dennison, Nicholas C Harvey, Cyrus Cooper, Julia L MacIsaac, Michael S Kobor, Harnish P Patel #, Keith M Godfrey #, Karen A Lillycrop #

Exogenous tetracosahexaenoic acid modifies the fatty acid composition of human primary T lymphocytes and Jurkat T cell leukemia cells contingent on cell type

外源性二十四碳六烯酸根据细胞类型改变人类原代 T 淋巴细胞和 Jurkat T 细胞白血病细胞的脂肪酸组成

Nicola A Irvine, Annette L West, Johanna Von Gerichten, Elizabeth A Miles, Karen A Lillycrop, Philip C Calder, Barbara A Fielding, Graham C Burdge

Modification of subcutaneous white adipose tissue inflammation by omega-3 fatty acids is limited in human obesity-a double blind, randomised clinical trial

ω-3脂肪酸对人类肥胖患者皮下白色脂肪组织炎症的调节作用有限——一项双盲随机临床试验

Fisk, Helena L; Childs, Caroline E; Miles, Elizabeth A; Ayres, Robert; Noakes, Paul S; Paras-Chavez, Carolina; Kuda, Ondrej; Kopecký, Jan; Antoun, Elie; Lillycrop, Karen A; Calder, Philip C