Lim Chang-Uk相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Host-derived interleukin-1Î± drives tumor immunosuppression by reprogramming tumor-associated myeloid cells.

宿主来源的白细胞介素-1α通过重编程肿瘤相关髓系细胞来驱动肿瘤免疫抑制。

期刊:NPJ Breast Cancer

影响因子:7.6

doi:10.1038/s41523-026-00890-8

Keerthi Raja Manikanda Raja, Gupta Gourab, Atkinson Grace, Kathrein Katie, Armstrong Alissa, Gower R Michael, Roninson Igor B, Broude Eugenia V, Chen Mengqian, Ji Hao, Lim Chang-Uk, Wang Hongjun, Fan Daping, Xu Peisheng, Li Jie, Zhou Gang, Chen Hexin

细胞生物学

免疫/内分泌

发表日期：2026

文献求助收藏

CDK8/19 inhibition attenuates G1 arrest induced by BCR-ABL antagonists and accelerates death of chronic myelogenous leukemia cells.

CDK8/19 抑制可减弱 BCR-ABL 拮抗剂诱导的 G1 期阻滞，并加速慢性粒细胞白血病细胞的死亡

期刊:Cell Death Discovery

doi:10.1038/s41420-025-02339-6

Khamidullina Alvina I, Yastrebova Margarita A, Bruter Alexandra V, Nuzhina Julia V, Vorobyeva Nadezhda E, Khrustaleva Anastasia M, Varlamova Ekaterina A, Tyakht Alexander V, Abramenko Iaroslav E, Ivanova Ekaterina S, Zamkova Maria A, Li Jing, Lim Chang-Uk, Chen Mengqian, Broude Eugenia V, Roninson Igor B, Shtil Alexander A, Tatarskiy Victor V

细胞生物学

发表日期：2025

文献求助收藏

Mediator kinase inhibition reverses castration resistance of advanced prostate cancer

介质激酶抑制剂可逆转晚期前列腺癌的去势抵抗性

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI176709

Li, Jing; Hilimire, Thomas A; Liu, Yueying; Wang, Lili; Liang, Jiaxin; Gyorffy, Balazs; Sikirzhytski, Vitali; Ji, Hao; Zhang, Li; Cheng, Chen; Ding, Xiaokai; Kerr, Kendall R; Dowling, Charles E; Chumanevich, Alexander A; Mack, Zachary T; Schools, Gary P; Lim, Chang-Uk; Ellis, Leigh; Zi, Xiaolin; Porter, Donald C; Broude, Eugenia V; McInnes, Campbell; Wilding, George; Lilly, Michael B; Roninson, Igor B; Chen, Mengqian

发表日期：2024

文献求助收藏

The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs

抑制 CDK8/19 介导激酶可预防对 EGFR 靶向药物产生耐药性

影响因子:5.2

doi:10.3390/cells10010144

Sharko, Amanda C; Lim, Chang-Uk; McDermott, Martina S J; Hennes, Chuck; Philavong, Kingsavanh P; Aiken, Tiffanie; Tatarskiy, Victor V; Roninson, Igor B; Broude, Eugenia V

发表日期：2021

文献求助收藏

CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases

CDK8通过调节TIMP3和基质金属蛋白酶的基因表达，选择性地促进结肠癌肝转移的生长

期刊:Cancer Research

影响因子:16.6

doi:10.1158/0008-5472.CAN-18-1583

Liang, Jiaxin; Chen, Mengqian; Hughes, Daniel; Chumanevich, Alexander A; Altilia, Serena; Kaza, Vimala; Lim, Chang-Uk; Kiaris, Hippokratis; Mythreye, Karthikeyan; Pena, Maria Marjorette; Broude, Eugenia V; Roninson, Igor B

发表日期：2018

文献求助收藏

Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ 2 renders tumor cells dependent on its paralogous gene COPZ1

肿瘤特异性沉默编码衣壳蛋白复合物亚基ζ2的COPZ2基因，使肿瘤细胞依赖于其旁系同源基因COPZ1。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1103842108

Shtutman, Michael; Baig, Mirza; Levina, Elina; Hurteau, Gregory; Lim, Chang-Uk; Broude, Eugenia; Nikiforov, Mikhail; Harkins, Timothy T; Carmack, C Steven; Ding, Ye; Wieland, Felix; Buttyan, Ralph; Roninson, Igor B

细胞生物学

发表日期：2011

文献求助收藏

Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system

在灌注细胞培养系统中建立四碘甲状腺乙酸抗癌活性的药效学模型

期刊:PLoS Computational Biology

影响因子:3.6

doi:10.1371/journal.pcbi.1001073

Lin, Hung-Yun; Landersdorfer, Cornelia B; London, David; Meng, Ran; Lim, Chang-Uk; Lin, Cassie; Lin, Sharon; Tang, Heng-Yuan; Brown, David; Van Scoy, Brian; Kulawy, Robert; Queimado, Lurdes; Drusano, George L; Louie, Arnold; Davis, Faith B; Mousa, Shaker A; Davis, Paul J

细胞生物学

免疫/内分泌

发表日期：2011

文献求助收藏

The role of NBS1 in the modulation of PIKK family proteins ATM and ATR in the cellular response to DNA damage

NBS1在调节PIKK家族蛋白ATM和ATR对细胞DNA损伤反应中的作用

期刊:Cancer Letters

影响因子:10.1

doi:10.1016/j.canlet.2006.01.026

Zhou, Junqing; Lim, Chang Uk; Li, Jian Jian; Cai, Lu; Zhang, Ying

细胞生物学

发表日期：2006

文献求助收藏

Effect of a membrane-targeted sphingosine kinase 1 on cell proliferation and survival

膜靶向鞘氨醇激酶1对细胞增殖和存活的影响

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BJ20041726

Safadi-Chamberlain, Farida; Wang, Li-Ping; Payne, Shawn G; Lim, Chang-Uk; Stratford, Suzanne; Chavez, Jose Antonio; Fox, Michael H; Spiegel, Sarah; Summers, Scott A

细胞生物学

发表日期：2005

文献求助收藏