Lim Kyung-Eun相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Co-deletion of Lrp5 and Lrp6 in the skeleton severely diminishes bone gain from sclerostin antibody administration

骨骼中Lrp5和Lrp6的共同缺失会显著降低硬骨素抗体给药后的骨量增加。

doi:10.1016/j.bone.2020.115708

Lim, Kyung-Eun; Bullock, Whitney A; Horan, Daniel J; Williams, Bart O; Warman, Matthew L; Robling, Alexander G

发表日期：2021

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Pten deletion in Dmp1-expressing cells does not rescue the osteopenic effects of Wnt/β-catenin suppression

在表达Dmp1的细胞中敲除Pten并不能挽救Wnt/β-catenin抑制引起的骨质疏松效应。

期刊:Journal of Cellular Physiology

doi:10.1002/jcp.29792

Lim, Kyung-Eun; Hoggatt, April M; Bullock, Whitney A; Horan, Daniel J; Yokota, Hiroki; Pavalko, Frederick M; Robling, Alexander G

细胞生物学

发表日期：2020

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Independent validation of experimental results requires timely and unrestricted access to animal models and reagents

对实验结果进行独立验证需要及时、不受限制地获取动物模型和试剂。

期刊:PLoS Genetics

影响因子:3.7

doi:10.1371/journal.pgen.1008940

Diegel, Cassandra R; Hann, Steven; Ayturk, Ugur M; Hu, Jennifer C W; Lim, Kyung-Eun; Droscha, Casey J; Madaj, Zachary B; Foxa, Gabrielle E; Izaguirre, Isaac; Robling, Alexander G; Warman, Matthew L; Williams, Bart O

发表日期：2020

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Combination therapy in the Col1a2(G610C) mouse model of Osteogenesis Imperfecta reveals an additive effect of enhancing LRP5 signaling and inhibiting TGFβ signaling on trabecular bone but not on cortical bone

在成骨不全症的Col1a2(G610C)小鼠模型中，联合疗法显示增强LRP5信号传导和抑制TGFβ信号传导对小梁骨而非皮质骨具有叠加效应。

doi:10.1016/j.bone.2019.115084

Kaupp, Shannon; Horan, Dan J; Lim, Kyung-Eun; Feldman, Henry A; Robling, Alexander G; Warman, Matthew L; Jacobsen, Christina M

发表日期：2020

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Induction of Lrp5 HBM-causing mutations in Cathepsin-K expressing cells alters bone metabolism

在表达组织蛋白酶K的细胞中诱导Lrp5导致骨形成异常的突变会改变骨代谢。

doi:10.1016/j.bone.2018.10.007

Kang, Kyung Shin; Hong, Jung Min; Horan, Daniel J; Lim, Kyung-Eun; Bullock, Whitney A; Bruzzaniti, Angela; Hann, Steven; Warman, Matthew L; Robling, Alexander G

细胞生物学

发表日期：2019

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Sclerostin neutralization unleashes the osteoanabolic effects of Dkk1 inhibition

硬骨素中和作用可释放Dkk1抑制剂的骨合成代谢作用

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.98673

Witcher, Phillip C; Miner, Sara E; Horan, Daniel J; Bullock, Whitney A; Lim, Kyung-Eun; Kang, Kyung Shin; Adaniya, Alison L; Ross, Ryan D; Loots, Gabriela G; Robling, Alexander G

发表日期：2018

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Bone Mass and Strength are Significantly Improved in Mice Overexpressing Human WNT16 in Osteocytes.

在小鼠骨细胞中过表达人WNT16可显著提高小鼠的骨量和骨强度

期刊:Calcified Tissue International

影响因子:3.2

doi:10.1007/s00223-016-0225-4

Alam Imranul, Reilly Austin M, Alkhouli Mohammed, Gerard-O'Riley Rita L, Kasipathi Charishma, Oakes Dana K, Wright Weston B, Acton Dena, McQueen Amie K, Patel Bhavmik, Lim Kyung-Eun, Robling Alexander G, Econs Michael J

细胞生物学

发表日期：2017

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Adult-Onset Deletion of β-Catenin in (10kb)Dmp1-Expressing Cells Prevents Intermittent PTH-Induced Bone Gain

在表达(10kb)Dmp1的细胞中，成年期β-catenin的缺失可阻止间歇性PTH诱导的骨量增加。

期刊:Endocrinology

影响因子:3.3

doi:10.1210/en.2015-1587

Kedlaya, Rajendra; Kang, Kyung Shin; Hong, Jung Min; Bettagere, Vidya; Lim, Kyung-Eun; Horan, Daniel; Divieti-Pajevic, Paola; Robling, Alexander G

细胞生物学

发表日期：2016

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Osteoblast-Specific Overexpression of Human WNT16 Increases Both Cortical and Trabecular Bone Mass and Structure in Mice

人WNT16在成骨细胞中的特异性过表达可增加小鼠皮质骨和松质骨的质量和结构

期刊:Endocrinology

影响因子:3.3

doi:10.1210/en.2015-1281

Alam, Imranul; Alkhouli, Mohammed; Gerard-O'Riley, Rita L; Wright, Weston B; Acton, Dena; Gray, Amie K; Patel, Bhavmik; Reilly, Austin M; Lim, Kyung-Eun; Robling, Alexander G; Econs, Michael J

细胞生物学

发表日期：2016

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Core binding factor β of osteoblasts maintains cortical bone mass via stabilization of Runx2 in mice

成骨细胞核心结合因子β通过稳定Runx2来维持小鼠皮质骨量。

期刊:Journal of Bone and Mineral Research

影响因子:5.9

doi:10.1002/jbmr.2397

Lim, Kyung-Eun; Park, Na-Rae; Che, Xiangguo; Han, Min-Su; Jeong, Jae-Hwan; Kim, Shin-Yoon; Park, Clara Yongjoo; Akiyama, Haruhiko; Kim, Jung-Eun; Ryoo, Hyun-Mo; Stein, Janet L; Lian, Jane B; Stein, Gary S; Choi, Je-Yong

细胞生物学

发表日期：2015

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