日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Protocol to evaluate mouse brain spatial cell type-resolved transcriptomic discoveries using 10× Visium spatial transcriptomics and FLEX scRNA-seq.

使用 10× Visium 空间转录组学和 FLEX scRNA-seq 评估小鼠脑空间细胞类型解析转录组学发现的方案。

Burns Mara S, Miramontes Ricardo, Reidling John C, Lim Ryan G, Thompson Leslie M

Wild-type C9orf72 expression is a genetic modifier of C9-ALS survival

野生型C9orf72表达是C9-ALS生存的遗传修饰因子

Tsitkov, Stanislav; Raju, Akshay; Wu, Jie; Li, Jonathan; Lim, Ryan G; Wu, Zhuoxing; Bistami, Noura Al; Consortium, Answer Als; Van Eyk, Jennifer E; Svendsen, Clive N; Rothstein, Jeffrey D; Glass, Jonathan D; Finkbeiner, Steve; Kaye, Julia A; Thompson, Leslie M; Fraenkel, Ernest

Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics.

R6/2 HD 小鼠脑中独特的分子模式:来自时空转录组学的启示

Burns Mara S, Miramontes Ricardo, Wu Jie, Gulia Ravinder, Saddala Madhu S, Lau Alice L, Quach Tiffany, Reidling John C, Swarup Vivek, La Spada Albert R, Lim Ryan G, Thompson Leslie M

Dysregulation of protein SUMOylation networks in Huntington's disease R6/2 mouse striatum.

亨廷顿病 R6/2 小鼠纹状体中蛋白质 SUMO 化网络失调

Kachemov Marketta, Vaibhav Vineet, Smith Charlene, Sundararaman Niveda, Heath Marie, Pendlebury Devon F, Matlock Andrea, Lau Alice, Morozko Eva, Lim Ryan G, Reidling Jack, Steffan Joan S, Van Eyk Jennifer E, Thompson Leslie M

Identifying dysregulated regions in amyotrophic lateral sclerosis through chromatin accessibility outliers

通过染色质可及性异常值识别肌萎缩侧索硬化症中的异常调控区域

Çelik, Muhammed Hasan; Gagneur, Julien; Lim, Ryan G; Wu, Jie; Thompson, Leslie M; Xie, Xiaohui

Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization

亨廷顿病小鼠和人类脑组织均表现出G3BP1颗粒增多和TDP43错位

Sanchez, Isabella I; Nguyen, Thai B; England, Whitney E; Lim, Ryan G; Vu, Anthony Q; Miramontes, Ricardo; Byrne, Lauren M; Markmiller, Sebastian; Lau, Alice L; Orellana, Iliana; Curtis, Maurice A; Faull, Richard Lewis Maxwell; Yeo, Gene W; Fowler, Christie D; Reidling, Jack C; Wild, Edward J; Spitale, Robert C; Thompson, Leslie M

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

美国国立卫生研究院(NIH)项目“基于网络的细胞特征库”:人类细胞对扰动反应的系统级编目

Keenan, Alexandra B; Jenkins, Sherry L; Jagodnik, Kathleen M; Koplev, Simon; He, Edward; Torre, Denis; Wang, Zichen; Dohlman, Anders B; Silverstein, Moshe C; Lachmann, Alexander; Kuleshov, Maxim V; Ma'ayan, Avi; Stathias, Vasileios; Terryn, Raymond; Cooper, Daniel; Forlin, Michele; Koleti, Amar; Vidovic, Dusica; Chung, Caty; Schürer, Stephan C; Vasiliauskas, Jouzas; Pilarczyk, Marcin; Shamsaei, Behrouz; Fazel, Mehdi; Ren, Yan; Niu, Wen; Clark, Nicholas A; White, Shana; Mahi, Naim; Zhang, Lixia; Kouril, Michal; Reichard, John F; Sivaganesan, Siva; Medvedovic, Mario; Meller, Jaroslaw; Koch, Rick J; Birtwistle, Marc R; Iyengar, Ravi; Sobie, Eric A; Azeloglu, Evren U; Kaye, Julia; Osterloh, Jeannette; Haston, Kelly; Kalra, Jaslin; Finkbiener, Steve; Li, Jonathan; Milani, Pamela; Adam, Miriam; Escalante-Chong, Renan; Sachs, Karen; Lenail, Alex; Ramamoorthy, Divya; Fraenkel, Ernest; Daigle, Gavin; Hussain, Uzma; Coye, Alyssa; Rothstein, Jeffrey; Sareen, Dhruv; Ornelas, Loren; Banuelos, Maria; Mandefro, Berhan; Ho, Ritchie; Svendsen, Clive N; Lim, Ryan G; Stocksdale, Jennifer; Casale, Malcolm S; Thompson, Terri G; Wu, Jie; Thompson, Leslie M; Dardov, Victoria; Venkatraman, Vidya; Matlock, Andrea; Van Eyk, Jennifer E; Jaffe, Jacob D; Papanastasiou, Malvina; Subramanian, Aravind; Golub, Todd R; Erickson, Sean D; Fallahi-Sichani, Mohammad; Hafner, Marc; Gray, Nathanael S; Lin, Jia-Ren; Mills, Caitlin E; Muhlich, Jeremy L; Niepel, Mario; Shamu, Caroline E; Williams, Elizabeth H; Wrobel, David; Sorger, Peter K; Heiser, Laura M; Gray, Joe W; Korkola, James E; Mills, Gordon B; LaBarge, Mark; Feiler, Heidi S; Dane, Mark A; Bucher, Elmar; Nederlof, Michel; Sudar, Damir; Gross, Sean; Kilburn, David F; Smith, Rebecca; Devlin, Kaylyn; Margolis, Ron; Derr, Leslie; Lee, Albert; Pillai, Ajay

Selective binding of C-6 OH sulfated hyaluronic acid to the angiogenic isoform of VEGF(165)

C-6 OH硫酸化透明质酸与VEGF血管生成异构体的选择性结合(165)

Dong-Kwon Lim #, Ryan G Wylie #, Robert Langer, Daniel S Kohane