日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IL-33 expands plasma cells, disrupts germinal centers, and increases autoantibody production in mice

IL-33可扩增小鼠浆细胞,破坏生发中心,并增加自身抗体的产生。

Conde, Eva; Asrat, Seblewongel; Vecchione, Andrea; Gayvert, Kaitlyn; Pedraza, Paulina; Tasker, Carley; Huang, Sharon; Yarilin, Dmitry; Birchard, Dylan; Ben, Li-Hong; Lim, Wei Keat; Murphy, Andrew J; Sleeman, Matthew A; Limnander, Andre; Orengo, Jamie M

TRAPnSeq allows high-throughput profiling of antigen-specific antibody-secreting cells

TRAPnSeq技术能够对抗原特异性抗体分泌细胞进行高通量分析。

Seblewongel Asrat ,Joseph C Devlin ,Andrea Vecchione ,Brian Klotz ,Ian Setliff ,Devin Srivastava ,Andre Limnander ,Ashique Rafique ,Christina Adler ,Stephen Porter ,Andrew J Murphy ,Gurinder S Atwal ,Matthew A Sleeman ,Wei Keat Lim ,Jamie M Orengo

Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement

使用单克隆IgG抗体治疗猫过敏,这些抗体可以结合过敏原并阻止IgE的结合。

J M Orengo ,A R Radin ,V Kamat ,A Badithe ,L H Ben ,B L Bennett ,S Zhong ,D Birchard ,A Limnander ,A Rafique ,J Bautista ,A Kostic ,D Newell ,X Duan ,M C Franklin ,W Olson ,T Huang ,N A Gandhi ,L Lipsich ,N Stahl ,N J Papadopoulos ,A J Murphy ,G D Yancopoulos

Protein kinase Cδ promotes transitional B cell-negative selection and limits proximal B cell receptor signaling to enforce tolerance

蛋白激酶Cδ促进过渡性B细胞阴性选择,并限制近端B细胞受体信号传导以增强免疫耐受。

Limnander, Andre; Zikherman, Julie; Lau, Tannia; Leitges, Michael; Weiss, Arthur; Roose, Jeroen P

Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies

Rasgrp1突变增加幼稚T细胞CD44表达,并驱动mTOR依赖性的Helios⁺ T细胞和自身抗体的积累。

Daley, Stephen R; Coakley, Kristen M; Hu, Daniel Y; Randall, Katrina L; Jenne, Craig N; Limnander, Andre; Myers, Darienne R; Polakos, Noelle K; Enders, Anselm; Roots, Carla; Balakishnan, Bhavani; Miosge, Lisa A; Sjollema, Geoff; Bertram, Edward M; Field, Matthew A; Shao, Yunli; Andrews, T Daniel; Whittle, Belinda; Barnes, S Whitney; Walker, John R; Cyster, Jason G; Goodnow, Christopher C; Roose, Jeroen P

Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1

Ras特异性交换因子RasGRP1自身抑制的结构分析

Iwig, Jeffrey S; Vercoulen, Yvonne; Das, Rahul; Barros, Tiago; Limnander, Andre; Che, Yan; Pelton, Jeffrey G; Wemmer, David E; Roose, Jeroen P; Kuriyan, John

RasGRP Ras guanine nucleotide exchange factors in cancer

RasGRP Ras鸟嘌呤核苷酸交换因子在癌症中的作用

Ksionda, Olga; Limnander, Andre; Roose, Jeroen P

STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development

STIM1、PKC-δ 和 RasGRP 在 B 细胞发育过程中为促凋亡 Erk 信号传导设定阈值

Andre Limnander, Philippe Depeille, Tanya S Freedman, Jen Liou, Michael Leitges, Tomohiro Kurosaki, Jeroen P Roose, Arthur Weiss

SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome.

SOCS-1 定位于微管组织复合物相关的 20S 蛋白酶体

Vuong Bao Q, Arenzana Teresita L, Showalter Brian M, Losman Julie, Chen X Peter, Mostecki Justin, Banks Alexander S, Limnander Andre, Fernandez Neil, Rothman Paul B