日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immunoproteasome Inhibition Modulates Microglial Polarization to Facilitate Anti-Inflammatory Responses and Hematoma Resolution After Intracerebral Hemorrhage

免疫蛋白酶体抑制调节小胶质细胞极化,从而促进脑出血后的抗炎反应和血肿消退

Hu, Wei-Fen; Lee, Chien-Hui; Huang, Hsin-Yi; Pang, Cheng-Yoong; Wu, Yi-Feng; Lin, Tsung-Jen; Lin, Peter Bor-Chian; Tsai, Sheng-Tzung; Lin, Chia-Ho; Liew, Hock-Kean

The tumour suppressor RBM5 activates the helicase DHX15 to regulate splicing

肿瘤抑制因子RBM5激活解旋酶DHX15来调节剪接

Liu, Shiheng; Su, Tiantian; Huang, Jeffrey; Lin, Chia-Ho; Black, Douglas L; Damianov, Andrey; Zhou, Z Hong

Cancer-associated SF3B1 mutation K700E causes widespread changes in U2/branchpoint recognition without altering splicing

与癌症相关的SF3B1突变K700E导致U2/分支点识别发生广泛改变,但不改变剪接。

Damianov, Andrey; Lin, Chia-Ho; Zhang, Jian; Manley, James L; Black, Douglas L

The Rbfox1/LASR complex controls alternative pre-mRNA splicing by recognition of multipart RNA regulatory modules

Rbfox1/LASR复合物通过识别多部分RNA调控模块来控制前体mRNA的选择性剪接。

Peyda, Parham; Lin, Chia-Ho; Onwuzurike, Kelechi; Black, Douglas L

Alternative splicing of a chromatin modifier alters the transcriptional regulatory programs of stem cell maintenance and neuronal differentiation.

染色质修饰因子的选择性剪接会改变干细胞维持和神经元分化的转录调控程序

Nazim Mohammad, Lin Chia-Ho, Feng An-Chieh, Xiao Wen, Yeom Kyu-Hyeon, Li Mulin, Daly Allison E, Tan Xianglong, Vu Ha, Ernst Jason, Carey Michael F, Smale Stephen T, Black Douglas L

The splicing regulators RBM5 and RBM10 are subunits of the U2 snRNP engaged with intron branch sites on chromatin.

剪接调节因子 RBM5 和 RBM10 是 U2 snRNP 的亚基,与染色质上的内含子分支位点相互作用

Damianov Andrey, Lin Chia-Ho, Huang Jeffrey, Zhou Lin, Jami-Alahmadi Yasaman, Peyda Parham, Wohlschlegel James, Black Douglas L

The lncRNA Malat1 is trafficked to the cytoplasm as a localized mRNA encoding a small peptide in neurons

lncRNA Malat1 在神经元中以局部 mRNA 的形式转运至细胞质,编码一种小肽。

Xiao, Wen; Halabi, Reem; Lin, Chia-Ho; Nazim, Mohammad; Yeom, Kyu-Hyeon; Black, Douglas L

The Rbfox1/LASR complex controls alternative pre-mRNA splicing by recognition of multi-part RNA regulatory modules

Rbfox1/LASR复合物通过识别多部分RNA调控模块来控制前体mRNA的选择性剪接。

Peyda, Parham; Lin, Chia-Ho; Onwuzurike, Kelechi; Black, Douglas L

Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers

通路引导分析揭示侵袭性前列腺癌中Myc依赖的mRNA选择性剪接

Phillips, John W; Pan, Yang; Tsai, Brandon L; Xie, Zhijie; Demirdjian, Levon; Xiao, Wen; Yang, Harry T; Zhang, Yida; Lin, Chia Ho; Cheng, Donghui; Hu, Qiang; Liu, Song; Black, Douglas L; Witte, Owen N; Xing, Yi

Correction: The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation.

更正:剪接调节因子 PTBP2 控制着神经元成熟所需的胚胎剪接程序

Li Qin, Zheng Sika, Han Areum, Lin Chia-Ho, Stoilov Peter, Fu Xiang-Dong, Black Douglas L