Lin Hsing-Chieh相关文献与解析，生知库 | 链接生命科学的每一步

Sakolish Courtney, Lin Hsing-Chieh, Moyer Haley L, Ford Lucie C, Christen Charles H, Wetmore Barbara A, DeVito Michael J, Hewitt Philip, Ferguson Stephen S, Raad Farah, Rusyn Ivan, Chiu Weihsueh A

发表日期：2026

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Quantitative estimates of inter-individual variability for new approach methodologies-based systemic safety toolbox using a population-based human in vitro model

利用基于人群的人体体外模型，对基于新方法论的系统安全性工具箱进行个体间变异性的定量估计

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfag038

Alshammari, Ibrahim; Ford, Lucie C; Tsai, Han-Hsuan D; Lin, Hsing-Chieh; Negi, Chander K; Dickey, Allison N; Wright, Fred A; Middleton, Alistair M; Baltazar, Maria T; Reynolds, Joe; Cable, Sophie; Punt, Ans; Chiu, Weihsueh A; Rusyn, Ivan

发表日期：2026

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Fetal response to maternal exposures of environmental chemicals: Utility of a four-cell human feto-maternal interface organ-on-chip.

胎儿对母体暴露于环境化学物质的反应：四细胞人类胎儿-母体界面芯片器官的实用性。

期刊:Chemico-Biological Interactions

影响因子:5.4

doi:10.1016/j.cbi.2025.111782

Moyer Haley L, Kim SungJin, Lam Bowie P, Richardson Lauren S, Tsai Han-Hsuan D, Ford Lucie C, Lin Hsing-Chieh C, Chiu Weihsueh A, Menon Ramkumar, Han Arum, Rusyn Ivan

Derivation of human toxicokinetic parameters and internal threshold of toxicological concern for tenuazonic acid through a human intervention trial and hierarchical Bayesian population modeling

通过人体干预试验和分层贝叶斯群体模型推导替诺唑酸的人体毒代动力学参数和内部毒理学关注阈值。

期刊:Journal of Exposure Science and Environmental Epidemiology

影响因子:4.7

doi:10.1038/s41370-025-00746-6

Visintin, Lia; Lu, En-Hsuan; Lin, Hsing-Chieh; Bader, Yasmine; Nguyen, Truong Nhat; Michailidis, Thanos Mouchtaris; De Saeger, Sarah; Chiu, Weihsueh A; De Boevre, Marthe

发表日期：2025

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Comparative Analysis of Chemical Distribution Models for Quantitative In Vitro to In Vivo Extrapolation

体外定量外推至体内化学分布模型的比较分析

期刊:Toxics

影响因子:4.1

doi:10.3390/toxics13060439

Lin, Hsing-Chieh; Ford, Lucie C; Rusyn, Ivan; Chiu, Weihsueh A

发表日期：2025

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Comparative analysis of Caco-2 cells and human jejunal and duodenal enteroid-derived cells in gel- and membrane-based barrier models of intestinal permeability.

在基于凝胶和膜的肠道通透性屏障模型中，对 Caco-2 细胞和人空肠及十二指肠类器官衍生细胞进行比较分析

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfaf011

Moyer Haley L, Vergara Leoncio, Stephan Clifford, Sakolish Courtney, Ford Lucie C, Tsai Han-Hsuan D, Lin Hsing-Chieh, Chiu Weihsueh A, Villenave Remi, Hewitt Philip, Ferguson Stephen S, Rusyn Ivan

Bayesian toxicokinetic modeling of subcellular partitioning in grass carp exposed to copper nanoparticles and its implication for detoxification

利用贝叶斯毒物动力学模型研究草鱼暴露于铜纳米颗粒后的亚细胞分配及其对解毒的影响

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-23730-4

Lin, Hsing-Chieh; Tsai, Yu-Lin; Hsiao, Bing-Ru; Li, Li-Hsuan; Hsieh, Hsueh-Han; Liu, Tzu-Hu; Li, Chong-Wei; Chen, Wei-Yu

细胞生物学

发表日期：2025

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Comparative Analysis of Proximal Tubule Cell Sources for In Vitro Studies of Renal Proximal Tubule Toxicity.

肾近端小管细胞来源在肾近端小管毒性体外研究中的比较分析

期刊:Biomedicines

影响因子:3.9

doi:10.3390/biomedicines13030563

Sakolish Courtney, Tsai Han-Hsuan D, Lin Hsing-Chieh, Bajaj Piyush, Villenave Remi, Ferguson Stephen S, Stanko Jason P, Becker Richard A, Hewitt Philip, Chiu Weihsueh A, Rusyn Ivan

细胞生物学

发表日期：2025

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Human Small Intestinal Tissue Models to Assess Barrier Permeability: Comparative Analysis of Caco-2 Cells, Jejunal and Duodenal Enteroid-Derived Cells, and EpiIntestinal(TM) Tissues in Membrane-Based Cultures with and Without Flow.

人类小肠组织模型评估屏障通透性：在有无流动条件下，对 Caco-2 细胞、空肠和十二指肠类器官衍生细胞以及 EpiIntestinal(TM) 组织在膜基培养中的比较分析

期刊:Bioengineering-Basel

影响因子:3.8

doi:10.3390/bioengineering12080809

Moyer Haley L, Vergara Leoncio, Stephan Clifford, Sakolish Courtney, Lin Hsing-Chieh, Chiu Weihsueh A, Villenave Remi, Hewitt Philip, Ferguson Stephen S, Rusyn Ivan

Sensitivity Analysis of the Inputs for Bioactivity-Exposure Ratio Calculations in a NAM-Based Systemic Safety Toolbox

基于NAM的系统安全性工具箱中生物活性-暴露比计算输入参数的敏感性分析

期刊:

影响因子:

doi:10.1016/j.namjnl.2025.100056

Lin, Hsing-Chieh; Baltazar, Maria Teresa; Cable, Sophie; Ford, Lucie C; Middleton, Alistair; Nicol, Beate; Punt, Ans; Reynolds, Joe; Rusyn, Ivan; Chiu, Weihsueh A

发表日期：2025

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An in vitro-in silico workflow for predicting renal clearance of environmental chemicals and drugs.

用于预测环境化学物质和药物肾脏清除率的体外-计算机模拟工作流程。

Quantitative estimates of inter-individual variability for new approach methodologies-based systemic safety toolbox using a population-based human in vitro model

利用基于人群的人体体外模型，对基于新方法论的系统安全性工具箱进行个体间变异性的定量估计

Fetal response to maternal exposures of environmental chemicals: Utility of a four-cell human feto-maternal interface organ-on-chip.

胎儿对母体暴露于环境化学物质的反应：四细胞人类胎儿-母体界面芯片器官的实用性。

Derivation of human toxicokinetic parameters and internal threshold of toxicological concern for tenuazonic acid through a human intervention trial and hierarchical Bayesian population modeling

通过人体干预试验和分层贝叶斯群体模型推导替诺唑酸的人体毒代动力学参数和内部毒理学关注阈值。

Comparative Analysis of Chemical Distribution Models for Quantitative In Vitro to In Vivo Extrapolation

体外定量外推至体内化学分布模型的比较分析

Comparative analysis of Caco-2 cells and human jejunal and duodenal enteroid-derived cells in gel- and membrane-based barrier models of intestinal permeability.

在基于凝胶和膜的肠道通透性屏障模型中，对 Caco-2 细胞和人空肠及十二指肠类器官衍生细胞进行比较分析

Bayesian toxicokinetic modeling of subcellular partitioning in grass carp exposed to copper nanoparticles and its implication for detoxification

利用贝叶斯毒物动力学模型研究草鱼暴露于铜纳米颗粒后的亚细胞分配及其对解毒的影响

Comparative Analysis of Proximal Tubule Cell Sources for In Vitro Studies of Renal Proximal Tubule Toxicity.

肾近端小管细胞来源在肾近端小管毒性体外研究中的比较分析

Human Small Intestinal Tissue Models to Assess Barrier Permeability: Comparative Analysis of Caco-2 Cells, Jejunal and Duodenal Enteroid-Derived Cells, and EpiIntestinal(TM) Tissues in Membrane-Based Cultures with and Without Flow.

人类小肠组织模型评估屏障通透性：在有无流动条件下，对 Caco-2 细胞、空肠和十二指肠类器官衍生细胞以及 EpiIntestinal(TM) 组织在膜基培养中的比较分析

Sensitivity Analysis of the Inputs for Bioactivity-Exposure Ratio Calculations in a NAM-Based Systemic Safety Toolbox

基于NAM的系统安全性工具箱中生物活性-暴露比计算输入参数的敏感性分析