Sex-specific KDM6A-HNF4A-CREBH network controls lipoprotein cholesterol metabolism and atherosclerosis via epigenetic reprograming of hepatocytes
性别特异性的KDM6A-HNF4A-CREBH网络通过肝细胞的表观遗传重编程控制脂蛋白胆固醇代谢和动脉粥样硬化
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-70846-w
Chen, Lin; Kang, Zhanfang; Härdfeldt, Jennifer; Li, Ziyi; Pedrelli, Matteo; Li, Qi; Lyu, Ruining; Valina Allo, Philipp; Sych, Taras; Zheng, Xiangru; Lin, Peibin; Zeng, Jianwen; Huang, Zhiqiang; Garcia-Irigoyen, Oihane; Sukhanava, Sviatlana; Parini, Paolo; Bonnefond, Amélie; Sezgin, Erdinc; Angelin, Bo; Treuter, Eckardt; Fan, Rongrong
心血管
代谢
细胞生物学
表观遗传
CREB
KDM6A
动脉粥样硬化
