日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Aberrant N-glycosylation may be a therapeutic target in carriers of a common and highly pleiotropic variant in the manganese transporter ZIP8

异常的N-糖基化可能是锰转运蛋白ZIP8常见且具有高度多效性的变异携带者的治疗靶点。

Tomar, Vartika; Kang, Sa Do; Lin, Ruxian; Brant, Steven R; Lazarev, Mark; Tressler, Caitlin; Glunde, Kristine; Zachara, Natasha; Melia, Joanna

Differential regulation of NHE3 expression in type 1 and type 2 diabetic intestine: impaired endosomal regulation of NHE3 expression in type 1 diabetes

1型和2型糖尿病肠道中NHE3表达的差异性调控:1型糖尿病中NHE3表达的内体调控受损

Singh, Varsha; Lin, Ruxian; Sunuwar, Laxmi; Yang, Jianbo; Donowitz, Mark; Sarker, Rafiquel

Partially differentiated ileal and distal-colonic human F508del-cystic fibrosis-enteroids secrete fluid in response to forskolin and linaclotide.

部分分化的回肠和远端结肠人类 F508del-囊性纤维化-肠类器官在福斯克林和利那洛肽的作用下分泌液体

Rong Yan, Zhang Zixin, de Jonge Hugo R, Lin Ruxian, Yu Huimin, Sarker Rafiq, Boffelli Dario, Zwick Rachel K, Klein Ophir D, Tse Chung-Ming, Donowitz Mark, Singh Varsha

Partially differentiated enterocytes in ileal and distal-colonic human F508del-CF-enteroids secrete fluid in response to forskolin and linaclotide

回肠和远端结肠人F508del-CF肠类器官中部分分化的肠细胞在福斯克林和利那洛肽刺激下分泌液体。

Rong, Yan; Zhang, Zixin; de Jonge, Hugo R; Lin, Ruxian; Yu, Huimin; Sarker, Rafiq; Boffelli, Dario; Zwick, Rachel K; Klein, Ophir D; Tse, Ming; Donowitz, Mark; Singh, Varsha

Differential Regulation of NHE3 Expression in Type 1 and Type 2 Diabetic Intestine: Impaired Endosomal Regulation of NHE3 Expression in Type 1 Diabetes

1型和2型糖尿病肠道中NHE3表达的差异性调控:1型糖尿病中NHE3表达的内体调控受损

Singh, Varsha; Lin, Ruxian; Sunuwar, Laxmi; Yang, Jianbo; Donowitz, Mark; Sarker, Rafiquel

Farnesoid X receptor enhances epithelial ACE2 expression and inhibits virally induced IL-6 secretion: implications for intestinal symptoms of SARS-CoV-2

法尼醇X受体增强上皮细胞ACE2表达并抑制病毒诱导的IL-6分泌:对SARS-CoV-2肠道症状的意义

Smyth, Jessica S; Truong, Jennifer K; Rao, Anuradha; Lin, Ruxian; Foulke-Abel, Jennifer; Adorini, Luciano; Donowitz, Mark; Dawson, Paul A; Keely, Stephen J

Inhibition of CFTR-mediated intestinal chloride secretion as potential therapy for bile acid diarrhea

抑制CFTR介导的肠道氯离子分泌作为治疗胆汁酸腹泻的潜在疗法

Duan, Tianying; Cil, Onur; Tse, C Ming; Sarker, Rafiquel; Lin, Ruxian; Donowitz, Mark; Verkman, Alan S

Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins

苯并嘧啶并吡咯并噁嗪二酮CFTR抑制剂(R)-BPO-27用于治疗细菌肠毒素引起的腹泻的抗分泌治疗

Cil, Onur; Phuan, Puay-Wah; Gillespie, Anne Marie; Lee, Sujin; Tradtrantip, Lukmanee; Yin, Jianyi; Tse, Ming; Zachos, Nicholas C; Lin, Ruxian; Donowitz, Mark; Verkman, Alan S

Stress inhibits tryptophan hydroxylase expression in a rat model of depression

压力抑制抑郁症大鼠模型中色氨酸羟化酶的表达

Yi Chen, Haixia Xu, Mingyue Zhu, Kun Liu, Bo Lin, Ruxian Luo, Chuanbai Chen, Mengsen Li