Activation of σ-1 receptor mitigates estrogen withdrawal-induced anxiety/depressive-like behavior in mice via restoration of GABA/glutamate signaling and neuroplasticity in the hippocampus
激活 σ-1 受体可通过恢复海马中的 GABA/谷氨酸信号和神经可塑性来减轻小鼠雌激素戒断引起的焦虑/抑郁样行为
期刊:Journal of Pharmacological Sciences
影响因子:3
doi:10.1016/j.jphs.2024.02.003
Peng Ren, Jing-Ya Wang, Hong-Lei Chen, Yue Wang, Lin-Yu Cui, Jing-Yao Duan, Wen-Zhi Guo, Yong-Qi Zhao, Yun-Feng Li
信号转导
神经
抑郁症
焦虑症
GPCR/Calcium/cAMP
Neuroscience
