日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Correction: γ‑Secretase modulator resistance of an aggressive Alzheimer‑causing presenilin mutant can be overcome in the heterozygous patient state by a set of advanced compounds

更正：在杂合子患者状态下，可通过一系列先进化合物克服侵袭性阿尔茨海默病致病早老素突变体的γ-分泌酶调节剂耐药性。

期刊:Alzheimers Research & Therapy
影响因子:7.6
doi:10.1186/s13195-025-01723-9
Trambauer, Johannes; Sarmiento, Rosa Maria Rodriguez; Garringer, Holly J; Salbaum, Katja; Pedro, Liliana D; Crusius, Dennis; Vidal, Ruben; Ghetti, Bernardino; Paquet, Dominik; Baumann, Karlheinz; Lindemann, Lothar; Steiner, Harald
阿尔茨海默症
发表日期：2025
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Development and Characterization of a Novel α-Synuclein-PEST H4 Cell Line for Enhanced Drug Screening in α-Synucleinopathies.

开发和表征新型α-突触核蛋白-PEST H4细胞系，以增强α-突触核蛋白病药物筛选

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26157205
Carullo Nancy, Haellman Viktor, Gutbier Simon, Schlicht Sonja, Nguyen Thien Thuong, Blum Marti Rita, Hartz Philippe, Lindemann Lothar, Schukur Lina
细胞生物学
H4
发表日期：2025
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Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome

神经发育障碍药物研发：从脆性X综合征中汲取的经验教训

期刊:Nature Reviews Drug Discovery
影响因子:101.8
doi:10.1038/nrd.2017.221
Berry-Kravis, Elizabeth M; Lindemann, Lothar; Jønch, Aia E; Apostol, George; Bear, Mark F; Carpenter, Randall L; Crawley, Jacqueline N; Curie, Aurore; Des Portes, Vincent; Hossain, Farah; Gasparini, Fabrizio; Gomez-Mancilla, Baltazar; Hessl, David; Loth, Eva; Scharf, Sebastian H; Wang, Paul P; Von Raison, Florian; Hagerman, Randi; Spooren, Will; Jacquemont, Sébastien
发育与干细胞
神经科学
发表日期：2018
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Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results

mGluR5-NAM 巴西姆格鲁兰对脆性X综合征青少年和成人行为的影响：一项随机、双盲、安慰剂对照试验：FragXis II期研究结果

期刊:Neuropsychopharmacology
影响因子:7.1
doi:10.1038/npp.2017.177
Youssef, Eriene A; Berry-Kravis, Elizabeth; Czech, Christian; Hagerman, Randi J; Hessl, David; Wong, Chin Y; Rabbia, Michael; Deptula, Dennis; John, Amy; Kinch, Russell; Drewitt, Philip; Lindemann, Lothar; Marcinowski, Moritz; Langland, Rachel; Horn, Carsten; Fontoura, Paulo; Santarelli, Luca; Quiroz, Jorge A
mGluR5
发表日期：2018
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Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion

mGluR5在人类16p11.2染色体微缺失小鼠模型中的病理生理作用

期刊:Nature Neuroscience
影响因子:20
doi:10.1038/nn.3911
Tian, Di; Stoppel, Laura J; Heynen, Arnold J; Lindemann, Lothar; Jaeschke, Georg; Mills, Alea A; Bear, Mark F
mGluR5
发表日期：2015
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Differential effects of diazepam and MPEP on habituation and neuro-behavioural processes in inbred mice

地西泮和MPEP对近交系小鼠习惯化和神经行为过程的不同影响

期刊:Behavioral and Brain Functions
影响因子:3.3
doi:10.1186/1744-9081-8-30
Salomons, Amber R; Pinzon, Nathaly Espitia; Boleij, Hetty; Kirchhoff, Susanne; Arndt, Saskia S; Nordquist, Rebecca E; Lindemann, Lothar; Jaeschke, Georg; Spooren, Will; Ohl, Frauke
发表日期：2012
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Darkness reduces BDNF expression in the visual cortex and induces repressive chromatin remodeling at the BDNF gene in both hippocampus and visual cortex.

黑暗会降低视觉皮层中 BDNF 的表达，并诱导海马体和视觉皮层中 BDNF 基因的抑制性染色质重塑

期刊:Cellular and Molecular Neurobiology
影响因子:4.8
doi:10.1007/s10571-010-9544-6
Karpova Nina N, Rantamäki Tomi, Di Lieto Antonio, Lindemann Lothar, Hoener Marius C, Castrén Eero
信号转导
发表日期：2010
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