日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Therapeutic scheduling of WEE1 inhibition preserves T cell function and promotes immune control of HPV(+) tumors

合理安排WEE1抑制剂的治疗方案可以保护T细胞功能,并促进对HPV(+)肿瘤的免疫控制。

Liu, Ying; Zhang, Zhiheng; Tao, Yanshan; Rahgav, Lovely; Gray-Gaillard, Sophie; Hussaini, Yasser; Pan, Meijie; Shamber, Justine; Kwak, Jeff; Park, Simone L; Cramer, Jessica; Stoltz, Regina; Patria, Joseph; Swanger, Jherek; Liu, Kathryn; Sannigrahi, Malay Kumar; Houghton, A McGarry; Rodriguez, Cristina P; Carey, Ryan M; Brody, Robert; Rajasekaran, Karthik; Weinstein, Gregory; Linette, Gerald P; Carreno, Beatriz M; Painter, Mark M; Wherry, E John; Clurman, Bruce; Basu, Devraj; Diab, Ahmed

CD5 deletion enhances the antitumor activity of adoptive T cell therapies.

CD5 缺失可增强过继性 T 细胞疗法的抗肿瘤活性

Patel Ruchi P, Ghilardi Guido, Zhang Yunlin, Chiang Yi-Hao, Xie Wei, Guruprasad Puneeth, Kim Ki Hyun, Chun Inkook, Angelos Mathew G, Pajarillo Raymone, Hong Seok Jae, Lee Yong Gu, Shestova Olga, Shaw Carolyn, Cohen Ivan, Gupta Aasha, Vu Trang, Qian Dean, Yang Steven, Nimmagadda Aditya, Snook Adam E, Siciliano Nicholas, Rotolo Antonia, Inamdar Arati, Harris Jaryse, Ugwuanyi Ositadimma, Wang Michael, Carturan Alberto, Paruzzo Luca, Chen Linhui, Ballard Hatcher J, Blanchard Tatiana, Xu Chong, Abdel-Mohsen Mohamed, Gabunia Khatuna, Wysocka Maria, Linette Gerald P, Carreno Beatriz, Barrett David M, Teachey David T, Posey Avery D, Powell Daniel J Jr, Sauter C Tor, Pileri Stefano, Pillai Vinodh, Scholler John, Rook Alain H, Schuster Stephen J, Barta Stefan K, Porazzi Patrizia, Ruella Marco

Facts and Hopes in Immunotherapy Strategies Targeting Antigens Derived from KRAS Mutations

针对KRAS突变衍生抗原的免疫疗法策略的现状与展望

Linette, Gerald P; Bear, Adham S; Carreno, Beatriz M

On the Twentieth Anniversary of Dendritic Cell Vaccines - Riding the Next Wave

树突状细胞疫苗问世二十周年——引领下一波浪潮

Linette, Gerald P; Carreno, Beatriz M

A Phase I Study of Apolizumab, an Anti-HLA-DR ß-chain Monoclonal Antibody, in Patients With Solid Tumor Malignancies

Apolizumab(一种抗HLA-DR β链单克隆抗体)治疗实体瘤恶性肿瘤患者的I期研究

Fracasso, Paula M; Goodner, Sherry A; Wildi, Jonathan D; Naughton, Michael J; Linette, Gerald P; Govindan, Ramaswamy; Tan, Benjamin R; Blum, Kristie A; Jones, Gary J; Pearce, Tillman E; Levitt, Daniel J; Clamon, Gerald H

Avelumab in patients with previously treated metastatic Merkel cell carcinoma: long-term data and biomarker analyses from the single-arm phase 2 JAVELIN Merkel 200 trial

阿维鲁单抗治疗既往接受过治疗的转移性默克尔细胞癌患者:来自单臂 II 期 JAVELIN Merkel 200 试验的长期数据和生物标志物分析

D'Angelo, Sandra P; Bhatia, Shailender; Brohl, Andrew S; Hamid, Omid; Mehnert, Janice M; Terheyden, Patrick; Shih, Kent C; Brownell, Isaac; Lebbé, Celeste; Lewis, Karl D; Linette, Gerald P; Milella, Michele; Georges, Sara; Shah, Parantu; Ellers-Lenz, Barbara; Bajars, Marcis; Güzel, Gülseren; Nghiem, Paul T

Tumor-Infiltrating Lymphocytes in the Checkpoint Inhibitor Era

检查点抑制剂时代肿瘤浸润淋巴细胞

Linette, Gerald P; Carreno, Beatriz M

RNA-seq for identification of therapeutically targetable determinants of immune activation in human glioblastoma

利用RNA测序技术鉴定人类胶质母细胞瘤中免疫激活的治疗靶点决定因素

Bagley, Stephen J; Hwang, Wei-Ting; Brem, Steven; Linette, Gerald P; O'Rourke, Donald M; Desai, Arati S

Highlights from the Literature

文学作品亮点

Bagley, Stephen J; Desai, Arati S; Linette, Gerald P; June, Carl H; O'Rourke, Donald M; Viapiano, Mariano; Wright, Karen; Purow, Benjamin; Huse, Jason; Schiff, David

Relationship between physician-adjudicated adverse events and patient-reported health-related quality of life in a phase II clinical trial (NCT01143402) of patients with metastatic uveal melanoma

在转移性葡萄膜黑色素瘤患者的II期临床试验(NCT01143402)中,医生判定的不良事件与患者报告的健康相关生活质量之间的关系

Atkinson, Thomas M; Hay, Jennifer L; Shoushtari, Alexander; Li, Yuelin; Paucar, Daniel J; Smith, Sloane C; Kudchadkar, Ragini R; Doyle, Austin; Sosman, Jeffrey A; Quevedo, Jorge Fernando; Milhem, Mohammed M; Joshua, Anthony M; Linette, Gerald P; Gajewski, Thomas F; Lutzky, Jose; Lawson, David H; Lao, Christopher D; Flynn, Patrick J; Albertini, Mark R; Sato, Takami; Lewis, Karl; Marr, Brian; Abramson, David H; Dickson, Mark Andrew; Schwartz, Gary K; Carvajal, Richard D