日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PD-L1 interacts with Frizzled 6 to activate β-catenin and form a positive feedback loop to promote cancer stem cell expansion

PD-L1 与 Frizzled 6 相互作用激活 β-catenin 并形成正反馈回路,促进癌症干细胞扩增

Lingchen Fu, Jia Fan, Sudipa Maity, Grant McFadden, Yixin Shi, Wei Kong

PPARδ Mediates the Effect of Dietary Fat in Promoting Colorectal Cancer Metastasis

PPARδ介导膳食脂肪促进结直肠癌转移的作用

Dingzhi Wang #, Lingchen Fu #, Jie Wei #, Ying Xiong, Raymond N DuBois

Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice

前列腺素E2促进小鼠结直肠癌干细胞扩增和转移

Dingzhi Wang, Lingchen Fu, Haiyan Sun, Lixia Guo, Raymond N DuBois

A mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitation

丝裂原活化蛋白激酶/细胞外信号调节激酶激酶(MEK)依赖性转录程序控制氨基酸限制期间早期生长反应 1(EGR1)基因的激活

Jixiu Shan, Mukundh N Balasubramanian, William Donelan, Lingchen Fu, Jaclyn Hayner, Maria-Cecilia Lopez, Henry V Baker, Michael S Kilberg

Elevated cJUN expression and an ATF/CRE site within the ATF3 promoter contribute to activation of ATF3 transcription by the amino acid response

cJUN 表达升高和 ATF3 启动子内的 ATF/CRE 位点有助于通过氨基酸反应激活 ATF3 转录

Lingchen Fu, Michael S Kilberg

ATF4-dependent regulation of the JMJD3 gene during amino acid deprivation can be rescued in Atf4-deficient cells by inhibition of deacetylation

在氨基酸缺乏期间,ATF4 依赖的 JMJD3 基因调控可以通过抑制去乙酰化在 Atf4 缺乏的细胞中得到挽救

Jixiu Shan, Lingchen Fu, Mukundh N Balasubramanian, Tracy Anthony, Michael S Kilberg

Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-κB-inducing kinase while activating both canonical and alternative nuclear factor-κB pathways

弥漫性大 B 细胞淋巴瘤中的组成性 BR3 受体信号可稳定核因子-κB 诱导激酶,同时激活经典和替代核因子-κB 通路

Lan V Pham, Lingchen Fu, Archito T Tamayo, Carlos Bueso-Ramos, Elias Drakos, Francisco Vega, L Jeffrey Medeiros, Richard J Ford

Auto-activation of c-JUN gene by amino acid deprivation of hepatocellular carcinoma cells reveals a novel c-JUN-mediated signaling pathway

肝细胞癌细胞氨基酸剥夺导致 c-JUN 基因自激活,揭示了一条新的 c-JUN 介导的信号通路

Lingchen Fu, Mukundh Balasubramanian, Jixiu Shan, Elizabeth E Dudenhausen, Michael S Kilberg

BAFF-R promotes cell proliferation and survival through interaction with IKKbeta and NF-kappaB/c-Rel in the nucleus of normal and neoplastic B-lymphoid cells

BAFF-R 通过与正常和肿瘤性 B 淋巴细胞核中的 IKKbeta 和 NF-kappaB/c-Rel 相互作用促进细胞增殖和存活

Lingchen Fu, Yen-Chiu Lin-Lee, Lan V Pham, Archito T Tamayo, Linda C Yoshimura, Richard J Ford