日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metabolism and response to stress gene signatures reveal ulcerative colitis heterogeneity and identify patients with increased response to therapy

代谢和应激反应基因特征揭示了溃疡性结肠炎的异质性,并识别出对治疗反应增强的患者。

Linggi, Bryan; Filice, Melissa; Sangiorgi, Bruno; Smith, Michelle I; Teft, Wendy; Jairath, Vipul; Ma, Christopher; Vande Casteele, Niels

Spatial transcriptomics reveals unique inflammatory signatures across all anatomic locations in postoperative Crohn's disease

空间转录组学揭示了克罗恩病术后所有解剖部位独特的炎症特征

Battat, Robert; Sangiorgi, Bruno; Linggi, Bryan; Gui, Xianyong; Smith, Michelle I; Mehandru, Saurabh; Longman, Randy; Lukin, Dana J; Scherl, Ellen J; Qin, Lihui; Ma, Christopher; Teft, Wendy; Vande Casteele, Niels

CSL362 potently and specifically depletes pDCs invitro and ablates SLE-immune complex-induced IFN responses

CSL362 能高效且特异性地在体外清除浆细胞样树突状细胞 (pDC),并消除系统性红斑狼疮免疫复合物诱导的干扰素反应。

Katherine A Monaghan ,Alberta Hoi ,Cristina Gamell ,Tsin Yee Tai ,Bryan Linggi ,Jarrat Jordan ,Matteo Cesaroni ,Takahiro Sato ,Milica Ng ,Shereen Oon ,Jacqueline Benson ,Ian Wicks ,Eric Morand ,Nicholas Wilson

Meta-analysis of gene expression disease signatures in colonic biopsy tissue from patients with ulcerative colitis

对溃疡性结肠炎患者结肠活检组织中基因表达疾病特征进行荟萃分析

Linggi, Bryan; Jairath, Vipul; Zou, Guangyong; Shackelton, Lisa M; McGovern, Dermot P B; Salas, Azucena; Verstockt, Bram; Silverberg, Mark S; Nayeri, Shadi; Feagan, Brian G; Vande Casteele, Niels

Biomarkers of Crohn's Disease to Support the Development of New Therapeutic Interventions

克罗恩病生物标志物在支持新型治疗干预措施开发中的应用

Porter, Amy C; Aubrecht, Jiri; Birch, Chandler; Braun, Jonathan; Cuff, Carolyn; Dasgupta, Suryasarathi; Gale, Jeremy D; Hinton, Robert; Hoffmann, Steven C; Honig, Gerard; Linggi, Bryan; Schito, Marco; Casteele, Niels Vande; Sauer, John-Michael

Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease

抑癌素 M 驱动肠道炎症并预测炎症性肠病患者对肿瘤坏死因子中和疗法的反应

Nathaniel R West, Ahmed N Hegazy, Benjamin M J Owens, Samuel J Bullers, Bryan Linggi, Sofia Buonocore, Margherita Coccia, Dieter Görtz, Sébastien This, Krista Stockenhuber, Johanna Pott, Matthias Friedrich, Grigory Ryzhakov, Frédéric Baribaud, Carrie Brodmerkel, Constanze Cieluch, Nahid Rahman, Gerh

Inference of interactions in cyanobacterial-heterotrophic co-cultures via transcriptome sequencing.

通过转录组测序推断蓝藻-异养共培养物中的相互作用

Beliaev Alexander S, Romine Margie F, Serres Margrethe, Bernstein Hans C, Linggi Bryan E, Markillie Lye M, Isern Nancy G, Chrisler William B, Kucek Leo A, Hill Eric A, Pinchuk Grigoriy E, Bryant Donald A, Wiley H Steven, Fredrickson Jim K, Konopka Allan

CO2 exposure at pressure impacts metabolism and stress responses in the model sulfate-reducing bacterium Desulfovibrio vulgaris strain Hildenborough

在压力下暴露于二氧化碳会影响模式硫酸盐还原菌希尔登伯勒脱硫弧菌(Desulfovibrio vulgaris strain Hildenborough)的代谢和应激反应。

Wilkins, Michael J; Hoyt, David W; Marshall, Matthew J; Alderson, Paul A; Plymale, Andrew E; Markillie, L Meng; Tucker, Abby E; Walter, Eric D; Linggi, Bryan E; Dohnalkova, Alice C; Taylor, Ron C

Coregulation of Terpenoid Pathway Genes and Prediction of Isoprene Production in Bacillus subtilis Using Transcriptomics

利用转录组学研究枯草芽孢杆菌中萜类化合物合成途径基因的共调控及异戊二烯的产生预测

Becky M Hess ,Junfeng Xue, Lye Meng Markillie, Ronald C Taylor, H Steven Wiley, Birgitte K Ahring, Bryan Linggi

Changes in translational efficiency is a dominant regulatory mechanism in the environmental response of bacteria

翻译效率的变化是细菌环境响应中的主要调控机制。

Taylor, Ronald C; Webb Robertson, Bobbie-Jo M; Markillie, Lye Meng; Serres, Margrethe H; Linggi, Bryan E; Aldrich, Joshua T; Hill, Eric A; Romine, Margaret F; Lipton, Mary S; Wiley, H Steven