日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cross-coronavirus host susceptibility loci influence disease severity through immune mediators

冠状病毒宿主易感基因位点通过免疫介质影响疾病严重程度

Risemberg, Ellen L; Leist, Sarah R; Schäfer, Alexandra; Kamat, Kalika D; Bell, Timothy A; Hock, Pablo; Jensen, Kara L; Linnertz, Colton L; Miller, Darla R; Shaw, Ginger D; Pardo Manuel de Villena, Fernando; Baric, Ralph S; Ferris, Martin T; Valdar, William

Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice

宿主遗传变异指导小鼠丙型肝炎病毒清除、慢性病和肝纤维化

Ariane J Brown, John J Won, Raphael Wolfisberg, Ulrik Fahnøe, Nicholas Catanzaro, Ande West, Fernando R Moreira, Mariana Nogueira Batista, Martin T Ferris, Colton L Linnertz, Sarah R Leist, Cameron Nguyen, Gabriela De la Cruz, Bentley R Midkiff, Yongjuan Xia, Mia D Evangelista, Stephanie A Montgomer

A mutation in Themis contributes to anaphylaxis severity following oral peanut challenge in CC027 mice

CC027小鼠口服花生后,Themis基因突变导致过敏反应加重。

Risemberg, Ellen L; Smeekens, Johanna M; Cruz Cisneros, Marta C; Hampton, Brea K; Hock, Pablo; Linnertz, Colton L; Miller, Darla R; Orgel, Kelly; Shaw, Ginger D; de Villena, Fernando Pardo Manuel; Burks, A Wesley; Valdar, William; Kulis, Michael D; Ferris, Martin T

Genetic loci regulate Sarbecovirus pathogenesis: A comparison across mice and humans

基因位点调控沙贝病毒的致病性:小鼠和人类的比较

Schäfer, Alexandra; Gralinski, Lisa E; Leist, Sarah R; Hampton, Brea K; Mooney, Michael A; Jensen, Kara L; Graham, Rachel L; Agnihothram, Sudhakar; Jeng, Sophia; Chamberlin, Steven; Bell, Timothy A; Scobey, D Trevor; Linnertz, Colton L; VanBlargan, Laura A; Thackray, Larissa B; Hock, Pablo; Miller, Darla R; Shaw, Ginger D; Diamond, Michael S; de Villena, Fernando Pardo Manuel; McWeeney, Shannon K; Heise, Mark T; Menachery, Vineet D; Ferris, Martin T; Baric, Ralph S

Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice.

宿主-病原体基因相互作用是遗传多样性小鼠结核病易感性的基础

Smith Clare M, Baker Richard E, Proulx Megan K, Mishra Bibhuti B, Long Jarukit E, Park Sae Woong, Lee Ha-Na, Kiritsy Michael C, Bellerose Michelle M, Olive Andrew J, Murphy Kenan C, Papavinasasundaram Kadamba, Boehm Frederick J, Reames Charlotte J, Meade Rachel K, Hampton Brea K, Linnertz Colton L, Shaw Ginger D, Hock Pablo, Bell Timothy A, Ehrt Sabine, Schnappinger Dirk, Pardo-Manuel de Villena Fernando, Ferris Martin T, Ioerger Thomas R, Sassetti Christopher M

Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis

通过对 Collaborative Cross 中稳态抗体水平进行正向遗传筛选,发现 MBD1 是 B 细胞稳态的新型调节因子。

Hampton, Brea K; Plante, Kenneth S; Whitmore, Alan C; Linnertz, Colton L; Madden, Emily A; Noll, Kelsey E; Boyson, Samuel P; Parotti, Breantie; Xenakis, James G; Bell, Timothy A; Hock, Pablo; Shaw, Ginger D; de Villena, Fernando Pardo-Manuel; Ferris, Martin T; Heise, Mark T

Genetic basis of thermal nociceptive sensitivity and brain weight in a BALB/c reduced complexity cross

BALB/c 低复杂度杂交中热伤害感受敏感性和脑重量的遗传基础

Jacob A Beierle, Emily J Yao, Stanley I Goldstein, Julia L Scotellaro, Katherine D Sena, Colton A Linnertz, Adam B Willits, Leena Kader, Erin E Young, Gary Peltz, Andrew Emili, Martin T Ferris, Camron D Bryant

Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research

MiniMUGA基因分型芯片的内容和性能:提高小鼠研究严谨性和可重复性的新工具

Sigmon, John Sebastian; Blanchard, Matthew W; Baric, Ralph S; Bell, Timothy A; Brennan, Jennifer; Brockmann, Gudrun A; Burks, A Wesley; Calabrese, J Mauro; Caron, Kathleen M; Cheney, Richard E; Ciavatta, Dominic; Conlon, Frank; Darr, David B; Faber, James; Franklin, Craig; Gershon, Timothy R; Gralinski, Lisa; Gu, Bin; Gaines, Christiann H; Hagan, Robert S; Heimsath, Ernest G; Heise, Mark T; Hock, Pablo; Ideraabdullah, Folami; Jennette, J Charles; Kafri, Tal; Kashfeen, Anwica; Kulis, Mike; Kumar, Vivek; Linnertz, Colton; Livraghi-Butrico, Alessandra; Lloyd, K C Kent; Lutz, Cathleen; Lynch, Rachel M; Magnuson, Terry; Matsushima, Glenn K; McMullan, Rachel; Miller, Darla R; Mohlke, Karen L; Moy, Sheryl S; Murphy, Caroline E Y; Najarian, Maya; O'Brien, Lori; Palmer, Abraham A; Philpot, Benjamin D; Randell, Scott H; Reinholdt, Laura; Ren, Yuyu; Rockwood, Steve; Rogala, Allison R; Saraswatula, Avani; Sassetti, Christopher M; Schisler, Jonathan C; Schoenrock, Sarah A; Shaw, Ginger D; Shorter, John R; Smith, Clare M; St Pierre, Celine L; Tarantino, Lisa M; Threadgill, David W; Valdar, William; Vilen, Barbara J; Wardwell, Keegan; Whitmire, Jason K; Williams, Lucy; Zylka, Mark J; Ferris, Martin T; McMillan, Leonard; Manuel de Villena, Fernando Pardo

A cytosine-thymine (CT)-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer's disease and affects SNCA expression

SNCA基因第4内含子中富含胞嘧啶-胸腺嘧啶(CT)的单倍型会增加阿尔茨海默病中路易体病理的风险,并影响SNCA基因的表达。

Michael W Lutz,Robert Saul,Colton Linnertz,Omolara-Chinue Glenn,Allen D Roses,Ornit Chiba-Falek

The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes

阿尔茨海默病相关 poly-T 基因座对 TOMM40 和载脂蛋白 E 基因表达的顺式调控作用

Colton Linnertz, Lauren Anderson, William Gottschalk, Donna Crenshaw, Michael W Lutz, Jawara Allen, Sunita Saith, Mirta Mihovilovic, James R Burke, Kathleen A Welsh-Bohmer, Allen D Roses, Ornit Chiba-Falek