日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cross-coronavirus host susceptibility loci influence disease severity through immune mediators

冠状病毒宿主易感基因位点通过免疫介质影响疾病严重程度

Risemberg, Ellen L; Leist, Sarah R; Schäfer, Alexandra; Kamat, Kalika D; Bell, Timothy A; Hock, Pablo; Jensen, Kara L; Linnertz, Colton L; Miller, Darla R; Shaw, Ginger D; Pardo Manuel de Villena, Fernando; Baric, Ralph S; Ferris, Martin T; Valdar, William

A mutation in Themis contributes to anaphylaxis severity following oral peanut challenge in CC027 mice

CC027小鼠口服花生后,Themis基因突变导致过敏反应加重。

Risemberg, Ellen L; Smeekens, Johanna M; Cruz Cisneros, Marta C; Hampton, Brea K; Hock, Pablo; Linnertz, Colton L; Miller, Darla R; Orgel, Kelly; Shaw, Ginger D; de Villena, Fernando Pardo Manuel; Burks, A Wesley; Valdar, William; Kulis, Michael D; Ferris, Martin T

Sarbecovirus disease susceptibility is conserved across viral and host models

沙贝病毒疾病易感性在病毒和宿主模型中均得以保留

Leist, Sarah R; Schäfer, Alexandra; Risemberg, Ellen L; Bell, Timothy A; Hock, Pablo; Zweigart, Mark R; Linnertz, Colton L; Miller, Darla R; Shaw, Ginger D; de Villena, Fernando Pardo Manuel; Ferris, Martin T; Valdar, William; Baric, Ralph S

Genetic loci regulate Sarbecovirus pathogenesis: A comparison across mice and humans

基因位点调控沙贝病毒的致病性:小鼠和人类的比较

Schäfer, Alexandra; Gralinski, Lisa E; Leist, Sarah R; Hampton, Brea K; Mooney, Michael A; Jensen, Kara L; Graham, Rachel L; Agnihothram, Sudhakar; Jeng, Sophia; Chamberlin, Steven; Bell, Timothy A; Scobey, D Trevor; Linnertz, Colton L; VanBlargan, Laura A; Thackray, Larissa B; Hock, Pablo; Miller, Darla R; Shaw, Ginger D; Diamond, Michael S; de Villena, Fernando Pardo Manuel; McWeeney, Shannon K; Heise, Mark T; Menachery, Vineet D; Ferris, Martin T; Baric, Ralph S

A mutation in Themis contributes to peanut-induced oral anaphylaxis in CC027 mice

Themis基因突变导致CC027小鼠发生花生诱发的口服过敏反应

Risemberg, Ellen L; Smeekens, Johanna M; Cisneros, Marta C Cruz; Hampton, Brea K; Hock, Pablo; Linnertz, Colton L; Miller, Darla R; Orgel, Kelly; Shaw, Ginger D; de Villena, Fernando Pardo Manuel; Burks, A Wesley; Valdar, William; Kulis, Michael D; Ferris, Martin T

Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice.

宿主-病原体基因相互作用是遗传多样性小鼠结核病易感性的基础

Smith Clare M, Baker Richard E, Proulx Megan K, Mishra Bibhuti B, Long Jarukit E, Park Sae Woong, Lee Ha-Na, Kiritsy Michael C, Bellerose Michelle M, Olive Andrew J, Murphy Kenan C, Papavinasasundaram Kadamba, Boehm Frederick J, Reames Charlotte J, Meade Rachel K, Hampton Brea K, Linnertz Colton L, Shaw Ginger D, Hock Pablo, Bell Timothy A, Ehrt Sabine, Schnappinger Dirk, Pardo-Manuel de Villena Fernando, Ferris Martin T, Ioerger Thomas R, Sassetti Christopher M

Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis

通过对 Collaborative Cross 中稳态抗体水平进行正向遗传筛选,发现 MBD1 是 B 细胞稳态的新型调节因子。

Hampton, Brea K; Plante, Kenneth S; Whitmore, Alan C; Linnertz, Colton L; Madden, Emily A; Noll, Kelsey E; Boyson, Samuel P; Parotti, Breantie; Xenakis, James G; Bell, Timothy A; Hock, Pablo; Shaw, Ginger D; de Villena, Fernando Pardo-Manuel; Ferris, Martin T; Heise, Mark T