日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning.

通过深度突变扫描绘制MET受体酪氨酸激酶的激酶结构域抗性机制图谱

Estevam Gabriella O, Linossi Edmond, Rao Jingyou, Macdonald Christian B, Ravikumar Ashraya, Chrispens Karson M, Capra John A, Coyote-Maestas Willow, Pimentel Harold, Collisson Eric A, Jura Natalia, Fraser James S

Autoregulation of the MET receptor tyrosine kinase by its intracellular juxtamembrane domain

MET受体酪氨酸激酶通过其胞内近膜结构域进行自身调节

Linossi, Edmond M; Espinoza, Carla A; Estevam, Gabriella O; Fraser, James S; Jura, Natalia

Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain

通过对MET受体酪氨酸激酶结构域进行深度突变扫描,揭示了近膜结构域和激酶N叶中的保守调控基序。

Estevam, Gabriella O; Linossi, Edmond M; Macdonald, Christian B; Espinoza, Carla A; Michaud, Jennifer M; Coyote-Maestas, Willow; Collisson, Eric A; Jura, Natalia; Fraser, James S

State of the structure address on MET receptor activation by HGF

HGF激活MET受体的结构地址状态

Linossi, Edmond M; Estevam, Gabriella O; Oshima, Masaya; Fraser, James S; Collisson, Eric A; Jura, Natalia

SAT-136 Hypoxia Effect on Cytokine Production by Breast Cancer Cells

SAT-136 低氧对乳腺癌细胞细胞因子产生的影响

Linossi, Edmond M; Babon, Jeffrey J; Hilton, Douglas J; Nicholson, Sandra E; Avtanski, Dimiter; Chen, Karin; Satlof, Leo; Stoffels, Guillaume; Kothapalli, Udithi; Ziluck, Noah; Lema, Maribel; Poretsky, Leonid

Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1

细胞因子信号抑制因子 (SOCS) 5 利用不同的结构域来调节 JAK1 并与衔接蛋白 Shc-1 相互作用。

Linossi, Edmond M; Chandrashekaran, Indu R; Kolesnik, Tatiana B; Murphy, James M; Webb, Andrew I; Willson, Tracy A; Kedzierski, Lukasz; Bullock, Alex N; Babon, Jeffrey J; Norton, Raymond S; Nicola, Nicos A; Nicholson, Sandra E