文献库，生知库 | 链接生命科学的每一步

日期影响因子

Nuclear-import receptors remodel the dilute phase to suppress phase transitions of RNA-binding proteins with prion-like domains

核输入受体重塑稀相，以抑制具有朊病毒样结构域的RNA结合蛋白的相变。

doi:10.1101/2025.11.14.688546

Linsenmeier, Miriam; Shinn, Min Kyung; Mumford, Thomas R; Liu, Vicky; Bugaj, Lukasz J; Pappu, Rohit V; Shorter, James

发表日期：2025

文献求助收藏

Scouring the human Hsp70 network uncovers diverse chaperone safeguards buffering TDP-43 toxicity.

对人类 Hsp70 网络的深入研究揭示了多种分子伴侣保护机制，可以缓冲 TDP-43 的毒性

doi:10.1101/2025.05.10.653282

Barbieri Edward M, Linsenmeier Miriam, Whiteman Katherine R, Cheng Yan, Braganza Sylvanne, Copley Katie E, Miranda-Castrodad Paola, Lewis Brennen, VillafaÃ±e Kevin, Amado Defne A, Davidson Beverly L, Shorter James

发表日期：2025

文献求助收藏

Nuclear-import receptors as gatekeepers of pathological phase transitions in ALS/FTD

核输入受体在ALS/FTD病理阶段转变中扮演着关键角色

期刊:Molecular Neurodegeneration

影响因子:17.5

doi:10.1186/s13024-023-00698-1

Khalil, Bilal; Linsenmeier, Miriam; Smith, Courtney L; Shorter, James; Rossoll, Wilfried

发表日期：2024

文献求助收藏

The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils

hnRNPA1低复杂度结构域的凝聚体界面促进淀粉样原纤维的形成

期刊:Nature Chemistry

影响因子:20.2

doi:10.1038/s41557-023-01289-9

Linsenmeier, Miriam; Faltova, Lenka; Morelli, Chiara; Capasso Palmiero, Umberto; Seiffert, Charlotte; Küffner, Andreas M; Pinotsi, Dorothea; Zhou, Jiangtao; Mezzenga, Raffaele; Arosio, Paolo

发表日期：2023

文献求助收藏

Dynamic arrest and aging of biomolecular condensates are modulated by low-complexity domains, RNA and biochemical activity

生物分子凝聚体的动态停滞和老化受低复杂度结构域、RNA和生化活性调控。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-022-30521-2

Linsenmeier, Miriam; Hondele, Maria; Grigolato, Fulvio; Secchi, Eleonora; Weis, Karsten; Arosio, Paolo

发表日期：2022

文献求助收藏

Examination of SOD1 aggregation modulators and their effect on SOD1 enzymatic activity as a proxy for potential toxicity

检测SOD1聚集调节剂及其对SOD1酶活性的影响，以此作为潜在毒性的指标

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.202000948R

Malik, Ravinder; Corrales, Christian; Linsenmeier, Miriam; Alalami, Huda; Sepanj, Niki; Bitan, Gal

发表日期：2020

文献求助收藏

The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations

癌症基因组的暗物质：调控元件、非翻译区、剪接位点、非编码RNA和同义突变的异常

期刊:EMBO Molecular Medicine

影响因子:8.3

doi:10.15252/emmm.201506055

Diederichs, Sven; Bartsch, Lorenz; Berkmann, Julia C; Fröse, Karin; Heitmann, Jana; Hoppe, Caroline; Iggena, Deetje; Jazmati, Danny; Karschnia, Philipp; Linsenmeier, Miriam; Maulhardt, Thomas; Möhrmann, Lino; Morstein, Johannes; Paffenholz, Stella V; Röpenack, Paula; Rückert, Timo; Sandig, Ludger; Schell, Maximilian; Steinmann, Anna; Voss, Gjendine; Wasmuth, Jacqueline; Weinberger, Maria E; Wullenkord, Ramona

发表日期：2016

文献求助收藏