日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Allele-selective von Willebrand factor silencing

等位基因选择性血管性血友病因子沉默

Eikenboom, Jeroen; Linthorst, Noa; Jongejan, Yvonne

Amelioration of a von Willebrand disease type 2B phenotype in vivo upon treatment with allele-selective siRNAs.

用等位基因选择性siRNA治疗后,体内血管性血友病2B型表型得到改善

Linthorst Noa A, Jongejan Yvonne K, Dirven Richard J, Laan Sebastiaan N J, Bierings Ruben, Casari Caterina, Cordfunke Robert A, Dahlman James E, Dolezal Natasja, Drijfhout Jan Wouter, Leebeek Frank W G, Ruhaak L Renee, Schrader Echeverri Elisa, Voorberg Jan, van Vlijmen Bart J M, Denis Cécile V, Eikenboom Jeroen C J

Detection of human cytomegalovirus cell-free DNA in pregnant women with symptomatically infected fetuses: proof-of-concept study

检测妊娠期妇女体内人巨细胞病毒游离DNA及其感染症状胎儿:概念验证研究

Faas, B H W; Meuleman, T; Astuti, G; Reuss, A; Stol, K; Sistermans, E A; Linthorst, J; van Leeuwen, E; Rahamat-Langendoen, J; Wilmink, F A

The future of siRNA-mediated approaches to treat von Willebrand disease

siRNA介导疗法治疗血管性血友病的未来

Linthorst, Noa A; van Vlijmen, Bart J M; Eikenboom, Jeroen C J

Protocol for high-precision CRISPR-Cas12a-based SNV detection on synthetic DNA, cell line cfDNA models, and liquid biopsies

用于合成DNA、细胞系cfDNA模型和液体活检的高精度CRISPR-Cas12a基SNV检测方案

Kavish A V Kohabir ,Jasper Linthorst ,Rob M F Wolthuis ,Erik A Sistermans

Early detection of active Human CytomegaloVirus (hCMV) infection in pregnant women using data generated for noninvasive fetal aneuploidy testing

利用无创胎儿非整倍体检测生成的数据,早期发现孕妇体内活动性人巨细胞病毒 (hCMV) 感染

Faas, Brigitte H W; Astuti, Galuh; Melchers, Willem J G; Reuss, Annette; Gilissen, Christian; Macville, Merryn V E; Ghesquiere, Stijn A I; Houben, Leonieke M H; Srebniak, Malgorzata Ilona; Geeven, Geert; Rahamat-Langendoen, Janette C; Sistermans, Erik A; Linthorst, Jasper

Synthetic mismatches enable specific CRISPR-Cas12a-based detection of genome-wide SNVs tracked by ARTEMIS

合成错配能够实现基于 CRISPR-Cas12a 的特异性检测,从而追踪 ARTEMIS 所追踪的全基因组 SNV。

Kavish A V Kohabir ,Jasper Linthorst ,Lars O Nooi ,Rick Brouwer ,Rob M F Wolthuis ,Erik A Sistermans

Small interfering RNA-mediated allele-selective silencing of von Willebrand factor in vitro and in vivo

小干扰 RNA 介导的体内外血管性血友病因子等位基因选择性沉默

Yvonne K Jongejan, Elisa Schrader Echeverri, Richard J Dirven, Kalina Paunovska, Noa A Linthorst, Annika de Jong, Johannes C Wellershoff, Kim D van der Gouw, Bart J M van Vlijmen, James E Dahlman, Jeroen C J Eikenboom

Physical Function and Physical Activity in Older Breast Cancer Survivors: 5-Year Follow-Up from the Climb Every Mountain Study

老年乳腺癌幸存者的身体机能和身体活动:来自“攀登每一座山”研究的5年随访

Lemij, Annelieke A; Liefers, Gerrit Jan; Derks, Marloes G M; Bastiaannet, Esther; Fiocco, Marta; Lans, Titia E; van der Pol, Carmen C; Vulink, Annelie J E; van Gerven, Leander; Guicherit, Onno R; Linthorst-Niers, Eugenie M H; Merkus, Jos W S; van Dalen, Thijs; Portielje, Johanneke E A; de Glas, Nienke A

SARS-CoV-2 Spike N-Terminal Domain Engages 9- O-Acetylated α2-8-Linked Sialic Acids

SARS-CoV-2 刺突 N 端结构域与 9-O-乙酰化 α2-8-连接唾液酸结合

Ilhan Tomris, Luca Unione, Linh Nguyen, Pouya Zaree, Kim M Bouwman, Lin Liu, Zeshi Li, Jelle A Fok, María Ríos Carrasco, Roosmarijn van der Woude, Anne L M Kimpel, Mirte W Linthorst, Sinan E Kilavuzoglu, Enrico C J M Verpalen, Tom G Caniels, Rogier W Sanders, Balthasar A Heesters, Roland J Pieters,