日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Directed Evolution of an Efficient Polycarbonate Depolymerase With Exceptional Operational Stability

定向进化获得高效聚碳酸酯解聚酶及其优异的操作稳定性

Jones, Henry A; Hutton, Amy E; Harris-Jukes, Dominic; Davidson, John; Johannissen, Linus O; Levy, Colin W; Shaver, Michael P; Green, Anthony P

Expanding the substrate scope of a bacterial monoterpene synthase for the production of sesquiterpenoid and diterpenoid products

拓展细菌单萜合酶的底物范围,用于生产倍半萜和二萜类化合物

Nicole G H Leferink,Joshua N Whitehead,Linus O Johannissen,Nigel S Scrutton

Engineered enzymes for enantioselective nucleophilic aromatic substitutions

用于对映选择性亲核芳香取代反应的工程酶

Lister, Thomas M; Roberts, George W; Hossack, Euan J; Zhao, Fei; Burke, Ashleigh J; Johannissen, Linus O; Hardy, Florence J; Millman, Alexander A V; Leys, David; Larrosa, Igor; Green, Anthony P

Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]-Cycloadditions

光敏剂重新定位提供了一种用于[2+2]环加成反应的对映体互补酶

Sun, Chuanjie; Kohn, Anna R; Smithson, Ross; Hardy, Florence J; Trimble, Jonathan S; Cao, Yuanxin; Johannissen, Linus O; Hay, Sam; Crawshaw, Rebecca; Green, Anthony P

Directed Evolution's Selective Use of Quantum Tunneling in Designed Enzymes─A Combined Theoretical and Experimental Study

定向进化在设计酶中对量子隧穿效应的选择性利用——理论与实验相结合的研究

Korchagina, Kseniia; Balasubramani, Sree Ganesh; Berreur, Jordan; Gerard, Emilie F; Johannissen, Linus O; Green, Anthony P; Hay, Sam; Schwartz, Steven D

A Machine Learning Model for the Prediction of Water Contact Angles on Solid Polymers

基于机器学习的固体聚合物水接触角预测模型

Sena, Jose; Johannissen, Linus O; Blaker, Jonny J; Hay, Sam

Photocobilins integrate B(12) and bilin photochemistry for enzyme control

光胆素整合维生素B12和胆素的光化学反应,从而控制酶活性。

Zhang, Shaowei; Jeffreys, Laura N; Poddar, Harshwardhan; Yu, Yuqi; Liu, Chuanyang; Patel, Kaylee; Johannissen, Linus O; Zhu, Lingyun; Cliff, Matthew J; Yan, Cunyu; Schirò, Giorgio; Weik, Martin; Sakuma, Michiyo; Levy, Colin W; Leys, David; Heyes, Derren J; Scrutton, Nigel S

A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme

非典型亲核试剂开启设计酶中的新机制途径

Amy E Hutton, Jake Foster, Rebecca Crawshaw, Florence J Hardy, Linus O Johannissen, Thomas M Lister, Emilie F Gérard, Zachary Birch-Price, Richard Obexer, Sam Hay, Anthony P Green

How Is Substrate Halogenation Triggered by the Vanadium Haloperoxidase from Curvularia inaequalis?

弯孢霉钒卤过氧化物酶如何触发底物卤化?

Gérard, Emilie F; Mokkawes, Thirakorn; Johannissen, Linus O; Warwicker, Jim; Spiess, Reynard R; Blanford, Christopher F; Hay, Sam; Heyes, Derren J; de Visser, Sam P

Decoding Catalysis by Terpene Synthases

解码萜烯合成酶的催化作用

Whitehead, Joshua N; Leferink, Nicole G H; Johannissen, Linus O; Hay, Sam; Scrutton, Nigel S