日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

In vitro activity of MRS-2541, a novel MetRS inhibitor, against a selection of resistant gram-positive organisms associated with serious hospital infections

体外实验表明，新型MetRS抑制剂MRS-2541对多种与严重医院感染相关的耐药革兰氏阳性菌具有活性。

期刊:Microbiology Spectrum
影响因子:3.8
doi:10.1128/spectrum.03615-25
Domagala, John; Jahanbakhsh, Seyedhameneh; Mendez, Angela K; Pillar, Chris M; Marra, Andrea; Hufnagel, David A; Molasky, Nora M R; Zhang, Zhongsheng; Fan, Erkang; Reyna, Dawn; Lipka, Elke; Buckner, Frederick S
炎症/感染
发表日期：2026
文献求助 收藏

A novel methionyl-tRNA synthetase inhibitor targeting gram-positive bacterial pathogens.

一种针对革兰氏阳性细菌病原体的新型甲硫氨酰-tRNA合成酶抑制剂

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00745-24
Molasky Nora M R, Zhang Zhongsheng, Gillespie J Robert, Domagala John, Reyna Dawn, Lipka Elke, Fan Erkang, Buckner Frederick S
微生物学
发表日期：2024
文献求助 收藏

NPP-669, a prodrug of cidofovir, is highly efficacious against human adenovirus infection in the permissive Syrian hamster model.

NPP-669 是西多福韦的前药，在易感叙利亚仓鼠模型中对人类腺病毒感染具有很高的疗效

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00489-24
Tollefson Ann E, Cline-Smith Anna B, Spencer Jacqueline F, Reyna Dawn M, Lipka Elke, Toth Karoly
Hamster
Human
发表日期：2024
文献求助 收藏

Longitudinal Monitoring of the Effects of Anti-Adenoviral Treatment Regimens in a Permissive In Vivo Model.

在允许的体内模型中对腺病毒治疗方案的效果进行纵向监测

期刊:Viruses-Basel
影响因子:3.5
doi:10.3390/v16081200
Tollefson Ann E, Cline-Smith Anna, Spencer Jacqueline F, Ying Baoling, Reyna Dawn M, Lipka Elke, James Scott H, Toth Karoly
Viral
发表日期：2024
文献求助 收藏

A five-day treatment course of zanamivir for the flu with a single, self-administered, painless microneedle array patch: Revolutionizing delivery of poorly membrane-permeable therapeutics

使用单片可自行注射、无痛的微针阵列贴片，即可完成为期五天的扎那米韦流感疗程：彻底革新膜渗透性差的药物递送方式

期刊:International Journal of Pharmaceutics
影响因子:5.2
doi:10.1016/j.ijpharm.2023.123081
Reyna, Dawn; Bejster, Ian; Chadderdon, Aaron; Harteg, Cheryl; Kurnia Anjani, Qonita; Hidayat Bin Sabri, Akmal; Brown, Ashley N; Drusano, George L; Westover, Jonna; Bart Tarbet, E; Vora, Lalitkumar K; Donnelly, Ryan F; Lipka, Elke
微生物学
流感
发表日期：2023
文献求助 收藏

A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo

一种经分子工程改造的抗病毒香蕉凝集素可抑制病毒融合，并在体内有效对抗流感病毒感染。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1915152117
Covés-Datson, Evelyn M; King, Steven R; Legendre, Maureen; Gupta, Auroni; Chan, Susana M; Gitlin, Emily; Kulkarni, Vikram V; Pantaleón García, Jezreel; Smee, Donald F; Lipka, Elke; Evans, Scott E; Tarbet, E Bart; Ono, Akira; Markovitz, David M
炎症/感染
流感
微生物学
发表日期：2020
文献求助 收藏

Biphasic Dissolution as an Exploratory Method During Early Drug Product Development

双相溶出法作为早期药物产品研发中的一种探索性方法

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics12050420
Silva, Daniela Amaral; Al-Gousous, Jozef; Davies, Neal M; Chacra, Nadia Bou; Webster, Gregory K; Lipka, Elke; Amidon, Gordon L; Löbenberg, Raimar
发表日期：2020
文献求助 收藏